Locally advanced prostate cancer
The role of radiotherapy in localised and locally advanced prostate cancer
... non-metastatic prostate cancer, the individualized recommendation of radiotherapy has to be the fruit of a multidisciplinary approach in the context of a Tumor Board, to be explained carefully to the ...
9
The modern role of androgen deprivation therapy in the management of localised and locally advanced prostate cancer
... There is strong evidence to support the use of ADT in combination with radiotherapy (RT) for men with locally advanced prostate cancer (T3/4 N+/- M0). The results of four major trials are ...
9
Retzius-sparing robot-assisted laparoscopic radical prostatectomy: functional and early oncologic results in aggressive and locally advanced prostate cancer
... in locally advanced PCa, studies have shown overall survival rates of > 75% at 10 years after RP ...surviving locally ad- vanced and high-risk ...
7
Prediction of pathological and oncological outcomes based on extended prostate biopsy results in patients with prostate cancer receiving radical prostatectomy: a single institution study
... or locally advanced prostate cancer has been revolutionized both for radical surgery and radiotherapy ...variable prostate-specific antigen levels, digital rectal exam- ination ...
8
Testosterone suppression in the treatment of recurrent or metastatic prostate cancer — A Canadian consensus statement
... or locally advanced prostate cancer with treatment via orchiectomy, or LHRH agonist (LHRHa) therapy plus a non-steroidal anti-androgen for at least 4 weeks [8, ...
20
Radiotherapy combined with hormonal therapy in prostate cancer: the state of the art
... Abstract: Androgen-deprivation therapy (ADT) is used routinely in combination with definitive external beam radiation therapy (EBRT) in patients with high-risk clinically localized or locally advanced ...
11
Intermittent versus continuous androgen deprivation for locally advanced, recurrent or metastatic prostate cancer: a systematic review and meta-analysis
... In recent years, non-randomized studies (most of them with heterogeneous criteria for selection and clinical as- sessment) were performed to confirm the effectiveness of intermittent androgen deprivation (IAD) in ...
14
Understanding locally advanced and advanced prostate cancer
... your cancer is no longer responding well to the hormone therapy that you are taking, your doctor may suggest you try a different hormone ...the cancer to grow, but the drugs work in different ...the ...
45
Six-month depot formulation of leuprorelin acetate in the treatment of prostate cancer
... of locally advanced and metastatic prostate cancer, as well as the adjuvant treatment of some patients with localized ...in advanced and metastatic prostate cancer ...of ...
9
Advanced Prostate Cancer: A Case Report
... Prostate cancer is common in men over 50 ...[5]. Prostate cancer can spread through the lymph and blood vessels, or by direct extension to nearby ...the prostate, is a marker of the ...
8
A Review of Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer
... rectal cancer (T1-T2N0) and over estimation of staging by preoperative clinical imaging [18], which will lead to certain blindness in selecting the treatment ...
10
Neoadjuvant treatment strategies for locally advanced rectal cancer
... with FU improved disease-free survival (DFS) (HR=0.75, CI: 0.68-0.83) and OS (HR 0.83, CI 0.76-0.91) [40]. However, a more recent meta-analysis of four trials which included preoperative radiotherapy, questions the ...
22
Prognostic value of neutrophil-to-lymphocyte ratio in advanced oesophago-gastric cancer: exploratory analysis of the REAL-2 trial
... The NLR and the PLR serve as surrogate markers for an underlying pro-in fl ammatory tumour micro-environment, though the exact mechanisms by which this process leads to poorer cancer outcomes remain uncertain. It ...
6
The p53 breast cancer tissue biomarker in Indian women
... Staining results were interpreted independently. In each case, the entire section was systemically examined under high-power fields (400 × ) for p53 immunoreactivity. Among all immunoreactive nuclei, only those clearly ...
8
Management of Locally Advanced Breast Cancer Fifty cases
... breast cancer, as described above, indicates that either the patient is cured by local treatment or that death occurs from metastatic disease at about the same time that she would have died without local ...
88
Le cancer de la prostate: Acquis et challenges pour l'an 2000
... Long term efficacy and safety of nilutamide plus castration in advanced prostate cancer and the significance of early prostate specific antigen normalization.. Comorbid[r] ...
10
A review of tasquinimod in the treatment of advanced prostate cancer
... a global modification in the epigenetic landscape, which is associated with gene-specific histone modifications induced at promoter regions of hypoxia-responsive genes. Treatment of prostate cancer cells ...
8
Quality of life, long-term survivors and long-term outcome from the ABC-02 study.
... Research on QoL in ABC is challenging. Assessing the QoL of ABC patients is critically important in a population who are often unwell from both local (obstructive jaundice, biliary sepsis, bowel obstruction and liver ...
7
Sipuleucel-T: immunotherapy for advanced prostate cancer
... of cancer vaccines is to use an antigen- containing vector (or the antigen itself) to activate an immune response against protein epitope/s expressed and displayed by tumor ...
12
Rationale for Modernising Imaging in Advanced Prostate Cancer.
... fluoride-labelled prostate- specific membrane antigen (PSMA), and F-fluciclovine (amino acid transportation; approved by the US Food and Drug Administration in 2016), that have variable geograph- ic availability ...
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