Long-term potentiation (LTP)
Cholinergic modulation of hippocampal long-term potentiation in chronic cerebral hypoperfused rats
... or long-term potentiation (LTP) is one of the most important neurochemical foundations in learning and memory, deficits of which occur as a result of ...and potentiation levels (p < ...
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Effects of inhaled anesthetic isoflurane on long-term potentiation of CA3 pyramidal cell afferents in vivo
... of long-term potentiation was attenuated in both control groups when compared to potentiated responses measured under sodium pentobarbital anesthesia (mean dif- ference in MF response compared to ...
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Seasonal variation of long term potentiation at a central synapse in the medicinal leech
... Long-term potentiation (LTP) is a persistent increase in synaptic transmission that is thought to contribute to a variety of adaptive processes including learning and ...elicit potentiation ...
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Protective Effects of Enriched Environment Against Transient Cerebral Ischemia-Induced Impairment of Passive Avoidance Memory and Long-Term Potentiation in Rats
... Hippocampus, a brain structure, has an essential func- tion in the brain network and is important for memory function. In addition, it is very sensitive to hypoxic- ischemic episodes (Erfani et al., 2015; Farkas, Luiten, ...
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Enhanced synaptic long-term potentiation in the anterior cingulate cortex of adult wild mice as compared with that in laboratory mice
... hippocampal long-term potentiation (LTP), behavioral learning as well as persistent ...undergo long-term upregulation in the brain under certain conditions including peripheral injury ...
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Effects of D amino acid oxidase inhibition on memory performance and long term potentiation in vivo
... The effects of DCS and SUN on the levels of long-term potentiation (LTP) recorded from the CA1 region of the rat hippocampus were evaluated in vivo. Male Spra- gue-Dawley rats (270–400 g) were ...
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Mechanistic target of rapamycin is necessary for changes in dendritic spine morphology associated with long-term potentiation
... Alterations in the strength of excitatory synapses in the hippocampus is believed to serve a vital function in the storage and recall of new information in the mammalian brain. These alterations involve the regulation of ...
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No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex
... One major interest in the study of transient receptor potential vanilloid type 1 (TRPV1) in sensory system is that it may serve as a drug target for treating chronic pain. While the roles of TRPV1 in peripheral ...
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A study of long-term potentiation in transgenic mice over-expressing mutant forms of both amyloid precursor protein and presenilin-1
... Mice expressing the human form of the APP 695 SWE mutation develop certain AD-like symptoms, such as increased Aβ deposits and plaques, increased glial cell number, and deficits in spatial memory learning tasks [9- 12]. ...
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X11beta rescues memory and long term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice
... A number of lines of evidence support the notion that altered APP processing leading to increased production, aggregation and deposition of Aβ are major pathogenic events in Alzheimer’s disease (see for review (2)). ...
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Stress and long term potentiation
... Long term potentiation (LTP) is a widely investigated phenomenon seen in several regions o f the central nervous system ...by long lasting increases in population spikes or o f glutamatergic ...
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Fructose 1,6-bisphosphatase 2-Camk2 interaction is an integral mechanism of long-term potentiation
... synaptic potentiation in excitatory ...synaptic potentiation resulted in a robust upregulation of sEPSC amplitude and frequency, and enlarged an average sEPSC area (Figure ...
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Expression mechanisms underlying different forms of hippocampal long-term potentiation
... It is now also recognised that three mechanistically distinct forms of LTP can be induced in situations where the cell type, animal age and other experimental conditions are kept constant (reviewed by Raymond, 2007). ...
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Long term potentiation decay and memory loss are mediated by AMPAR endocytosis
... regard, it is interesting to note that, in one of our previous studies, we observed that facilitated GluA2-dependent AMPAR endocy- tosis is associated with neuronal apoptosis produced by NMDA and ischemia-induced ...
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Antibodies prevent the acute inhibition of long term potentiation by amyloid beta in the rat hippocampus
... Co-injection of a dose of All that had no effect on LTP when injected on its own, prevented inhibition of LTP by purified cell-derived Ap oligomers, soluble synthetic Api.42 and an amylo[r] ...
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Frequency-specific stimulations induce reconsolidation of long-term potentiation in freely moving rats
... a long lasting potentiation, maintained for at least 2 weeks, in the population spike (PS) amplitude (PS-LTP) of the evoked fEPSP recorded from the electrode implanted in hippocampal DG (Repeated measures ...
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The involvement of metabotropic glutamate receptors in the induction of long-term potentiation in the medial frontal cortex of the rat
... activity long after the postsynaptic Ca^^ levels return to their baseline ...for long term changes in synaptic strength triggered by transient postsynaptic events (for review see Lisman, ...
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On the role of arachidonic acid in long-term potentiation
... Cooperativity, the requirement for sufficient activation in order to induce LTP, and associativity, the fact that activation of multiple independent inputs can perform this fimction, are now thought to be due to the ...
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Erythropoietin enhances hippocampal long-term potentiation and memory
... The long-lasting effect of EPO on neuroplasticity was con- firmed by analyses of paired-pulse facilitation, STP, LTP and STD, as well as of spontaneous synaptic activity in acute hippocampal slices, obtained from ...
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An investigation of the processes underlying late-phase long-term potentiation
... activity is paired with that of a strong input (M cNaughton et al., 1978; Levy and Steward, 1979). Input specificity - only those inputs that are activated at the time of the tetanus show potentiation (Andersen et ...
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