Macrophage accumulation in adipose tissue
Macrophage accumulation in adipose tissue is a
... Our findings have important implications for under- standing the obese state in vivo in that the specific nature of the nutrient leading to obesity could potentially result in different degrees of activation, or even ...
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Obesity is associated with macrophage accumulation in adipose tissue
... perigonadal adipose tissue from 24 mice in which adiposity varied due to sex, diet, and the obesity-related mutations agouti (A y ) and obese (Lep ob ...the macrophage content of adipose ...
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MCP 1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
... Furthermore, macrophage infiltration was apparent in adipose tissue of transgenic mice that overexpress MCP-1 in ...the macrophage accumulation in adipose tissue induced ...
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Adipocyte macrophage colony stimulating factor is a mediator of adipose tissue growth
... taneous adipose tissue was associated with increased tissue ...lipid accumulation. Histol- ogy and Glut4 immunoblotting confirmed the tissue to be adi- pose ...in adipose ...
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Macrophage derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice
... of macrophage production of human resistin is inflammation of WAT that is reminiscent of the inflam- mation seen in human ...The macrophage infiltration trig- gered by high-fat feeding is augmented by a ...
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Osteopontin mediates obesity induced adipose tissue macrophage infiltration and insulin resistance in mice
... and macrophage infiltration into adipose tissue, which may contribute to the development of insulin ...responses, tissue infiltration by macrophages is dependent on the expres- sion of ...
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Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity
... The accumulation in adipose tissue of macrophages in an inflammatory state is a hallmark of obesity-induced insulin ...reduced macrophage AMPK activity, acetyl-CoA carboxylase phosphorylation, ...
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Overexpression of scavenger receptor and infiltration of macrophage in epicardial adipose tissue of patients with ischemic heart disease and diabetes
... our data were from a single hospital and only small sam- ples of EAT were collected from each patient, being insuf- ficient for a thorough analysis and correlation between mRNA expression and protein. Due to the small ...
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Macrophage heterogeneity and tissue lipids
... in adipose tissue, and blood monocytes are recruited in increased numbers to sites of lipid accumulation in atherosclerosis, a modified form of inflammation in the arterial ...ameliorate ...
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Adipose tissue remodeling and obesity
... transient accumulation of lipid-laden ATMΦs (an increase of up to 65% of macrophage infiltration was ...of macrophage-specific genes, F4/80, CD38 and CSF-R1 ...the adipose back into ...
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Evaluation of macrophage plasticity in brown and white adipose tissue
... This is the author’s final, peer-reviewed manuscript as accepted for publication. The publisher-formatted version may be available through the publisher’s web site or your institution’s library. This item was retrieved ...
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Obesity induces a phenotypic switch in adipose tissue macrophage polarization
... SVF isolation and ATM purification. Epididymal fat pads from male C57BL/6 mice fed an ND or HFD were excised and minced in PBS with calcium chloride and 0.5% BSA. Tissue suspensions were centrifuged at 500 g for 5 ...
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Disabled homolog 2 controls macrophage phenotypic polarization and adipose tissue inflammation
... sustained tissue damage, increased expression of Dab2 during the resolution phase may be necessary for proper M2 polarization to prevent a switch back to the M1 ...of tissue macrophages to the M1 or M2 ...
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Accumulation and Changes in Composition of Collagens in Subcutaneous Adipose Tissue After Bariatric Surgery
... Accumulation and Changes in Composition of Collagens in Subcutaneous Adipose Tissue After Bariatric Surgery Yuejun Liu, Judith Aron-Wisnewsky, Genevi` eve Marcelin, Laurent Genser, Gilles Le Naour, ...
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Adipose tissue macrophages in aging associated adipose tissue function
... visceral adipose tissue of aged C57BL mice were significantly higher than those of young mice, while the expression of anti-inflammatory PPAR-γ was lower than that of young ...in adipose ...
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Targeting adipose tissue
... Brown adipose tissue physiology In contrast to WAT, brown adipose tissue (BAT) com- busts energy and releases heat. This unique function allows newborns to maintain body temperature in cold ...
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Brown adipose tissue
... brown adipose tissue, thermogenesis, UCP1, mitochondria, BATokine, browning, adipogenesis Obesity is currently a global pandemic and is associated with increased mortality and co-morbidities including many ...
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Influence of Age, Ethnicity and Sex on Body Composition Thresholds for the Accumulation of Visceral Adipose Tissue in Adults
... Abstract: The purpose of this study was to investigate the influence of age, ethnicity, and sex on the body fat percentage (BF%) threshold, the point above which visceral adipose tissue (VAT) increases more ...
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Visceral adipose tissue but not subcutaneous adipose tissue is associated with urine and serum metabolites
... (visceral adipose tissue (VAT), subcu- taneous adipose tissue (SAT), the ratio between VAT and SAT (VSR), body mass index (BMI), waist circumference (WC)) and urinary and serum metabolite ...
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Adipose tissue-derived serum amyloid A and adipose tissue macrophages in metabolic disease
... the adipose tissue can affect systemic insulin resistance, our results from the oral glucose tolerance test do still not rule out the possibility that adipose tissue production of human SAA1 ...
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