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mammary stem cell niche

Re evaluation of mammary stem cell biology based on in vivotransplantation

Re evaluation of mammary stem cell biology based on in vivotransplantation

... in mammary developmental biology and mammary neoplastic progression, and further to suggest biological events wherein our current level of ignorance could be addressed through thoughtful ...in ...

6

The bone metastasis niche in breast cancer– potential overlap with the haematopoietic stem cell niche in vivo

The bone metastasis niche in breast cancer– potential overlap with the haematopoietic stem cell niche in vivo

... perivascular niche areas broadly overlap in this re- ...tumour cell proliferation ...these cell types are likely to provide more dominant regulation of tumour cell dormancy/proliferation in ...

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The Role of Spy1 in Mammary Morphogenesis

The Role of Spy1 in Mammary Morphogenesis

... the mammary gland undergoes major changes in structure and function during pregnancy and lactation, where expression of Spy1 has been shown to be elevated during this period of development (Golipour et ...the ...

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Biophysical regulation of stem cell behavior within the niche

Biophysical regulation of stem cell behavior within the niche

... modulate cell diff erentiation has also been extended to analysis of the epithelial-mesenchymal transition (EMT) of both murine mammary gland cells and canine kidney epithelial cells, where more rigid ...

7

The stem cell niche: lessons from the Drosophila testis

The stem cell niche: lessons from the Drosophila testis

... hub cell specification was thought to occur late in ...hub cell fate (Okegbe and DiNardo, ...hub cell formation, is activated in posterior SGPs and restricts hub cell formation to the anterior ...

9

Hemmule: A Novel Structure with the Properties of the Stem Cell Niche

Hemmule: A Novel Structure with the Properties of the Stem Cell Niche

... large size cells, cells inside bone marrow vessels, cells around footprints, and are scattered around. 442.[r] ...

36

Original Article Comparison of different conditions for culturing of mesenchymal stem cells from human umbilical cord Wharton’s jelly

Original Article Comparison of different conditions for culturing of mesenchymal stem cells from human umbilical cord Wharton’s jelly

... four cell groups. Proliferative activities, cell cycle analysis, flow cytometric analysis, apoptosis anal- ysis, and the differentiation potential of these four cell populations were ...

16

The hematopoietic stem cell niche: from embryo to adult

The hematopoietic stem cell niche: from embryo to adult

... Hematopoietic stem cells (HSCs) are a rare cell population that sit at the top of the hematopoietic hierarchy; they have the capacity to self- renew and to differentiate to give rise to all blood ...

12

The stem cell niche finds its true north

The stem cell niche finds its true north

... the stem cell field is to improve health outcomes in ageing and ...of stem cell-based models of disease to the use of stem cells for cell-based ...adult cell types, it is ...

5

The aged niche disrupts muscle stem cell quiescence

The aged niche disrupts muscle stem cell quiescence

... efficiently deletes spry1 and increases a downstream transcriptional target of FGF signalling, erm in vivo (Supplementary Fig. 7). After a short-term deletion of spry1, the number of Pax7 + cells (Fig. 4b) and percentage ...

20

Signaling in the stem cell niche: regulating cell fate, function and plasticity

Signaling in the stem cell niche: regulating cell fate, function and plasticity

... self-renewing stem cell and proceeding through transit-amplifying cell stages before transitioning into the terminal differentiated state – was uncovered in the embryonic and hematopoietic ...

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A review paper on stem cells

A review paper on stem cells

... Hematopoietic stem cell transplants (SCT) were used in the treatment of neoplastic diseases, in addition to congenital, autoimmune, and inflammatory disorders (Talmadge, ...adult stem cells ...

8

Growth versus immunity : a redirection of the cell cycle?

Growth versus immunity : a redirection of the cell cycle?

... Although our knowledge is still fragmentary it is obvious that immunity can significantly affect hormone-cell cycle networks (Figure 1c,d). For instance, SA-mediated inhi- bition of growth might be directly ...

8

α6-Integrin alternative splicing: distinct cytoplasmic variants in stem cell fate specification and niche interaction

α6-Integrin alternative splicing: distinct cytoplasmic variants in stem cell fate specification and niche interaction

... common stem cell marker in diverse ...of stem cells within the niche, maintenance of stem cell stemness, regulation of stem cell differentiation, orientation of ...

7

Direct control of somatic stem cell proliferation factors by the Drosophila testis stem cell niche

Direct control of somatic stem cell proliferation factors by the Drosophila testis stem cell niche

... Stem cell proliferation and maintenance are typically regulated by niches: signalling microenvironments within tissues that allow resident stem cells to fulfil their functions (Scadden, ...2001), ...

12

Engrailed acts with Nejire to control decapentaplegic expression in the Drosophila ovarian stem cell niche

Engrailed acts with Nejire to control decapentaplegic expression in the Drosophila ovarian stem cell niche

... GSC niche is likely to be due to the different co-factor associated with ...the niche. Knocking down Nej activity in the niche compromises ...

8

Stem cell researchers find their niche

Stem cell researchers find their niche

... of cell division and ...for Stem Cell Research, Oslo, Norway), during mouse telencephalon development, Wnt signalling is normally restricted ...

5

Enabling stem cell therapies through synthetic stem cell–niche engineering

Enabling stem cell therapies through synthetic stem cell–niche engineering

... HSC niche. As a paradigm, a niche can be com- partmentalized into signaling pathways activated by soluble cytokines either secreted as autocrine ligands by stem cells themselves or in a paracrine ...

12

Vascular signalling mediated by ZWILLE potentiates WUSCHEL function
during shoot meristem stem cell development in the Arabidopsis
embryo

Vascular signalling mediated by ZWILLE potentiates WUSCHEL function during shoot meristem stem cell development in the Arabidopsis embryo

... the stem cell ...how niche development is regulated in the Arabidopsis ...family, stem cell-specific expression of the signal peptide gene CLAVATA3 ( CLV3 ) is not maintained despite ...

5

Adhesion in the stem cell niche: biological roles and regulation

Adhesion in the stem cell niche: biological roles and regulation

... adult stem cells reside in the body and undergo continuous self-renewal throughout an organism’s ...of stem cells, is collectively referred to as the stem cell niche (Spradling et ...

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