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maspin expression

Immunohistochemical Analysis of Maspin Expression in Chronic
Non Neoplastic and Neoplastic Colorectal Diseases: A Study of 70 Cases

Immunohistochemical Analysis of Maspin Expression in Chronic Non Neoplastic and Neoplastic Colorectal Diseases: A Study of 70 Cases

... studied expression of maspin in colorectal adenocarcinomas from 104 ...that maspin expression significantly correlated with the higher Dukes’ classification, depth of invasion and highgrade ...

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Nuclear maspin expression as a good prognostic factor in human epithelial ovarian carcinoma

Nuclear maspin expression as a good prognostic factor in human epithelial ovarian carcinoma

... of maspin, as well as its mecha- nism of action in numerous cancers, has not been ful- ly ...in maspin expression is associat- ed with the formation of metastases and poor clinical prognosis, in ...

9

Cytoplasmic maspin expression predicts poor prognosis of patients with soft tissue sarcomas

Cytoplasmic maspin expression predicts poor prognosis of patients with soft tissue sarcomas

... [5]. Maspin (mammary serine protease inhibitor) is a 42 kDa protein known to act as a tumor suppressor, and is a member of the serine protease inhibitor (serpin) ...of maspin has not been fully elucidated, ...

7

Original Article Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer

Original Article Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer

... on maspin expression sta- tus in stage II/III MSI-H CRC patients receiving fluoropyrimidine-based adjuvant chemothera- py, although the tendency towards a worse sur- vival of maspin-positive patients ...

9

Role of maspin expression in oral squamous cell carcinoma

Role of maspin expression in oral squamous cell carcinoma

... overall maspin expression in any form such as strong , moderate and weak was taken as positive and such positivity was documented in 29 cases of well differentiated SCC, 26 cases of moderately ...

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Maspin expression in gastrointestinal stromal tumors

Maspin expression in gastrointestinal stromal tumors

... Maspin expression has been shown in the literature in epithelial and myoepithelial cells in certain tissues, most notably in the breasts and prostate, as well as neoplasms stemming from these tissues ...

6

Original Article Expression of Snail transcription factor in prostatic adenocarcinoma in Egypt: correlation with Maspin protein expression and clinicopathologic variables

Original Article Expression of Snail transcription factor in prostatic adenocarcinoma in Egypt: correlation with Maspin protein expression and clinicopathologic variables

... Snail expression in prostatic ade- nocarcinoma and its prognostic value in human clinical ...Snail expression in BPH as well as normal prostatic tissue while focal weak expression was noted in HGPIN ...

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Original Article High frequency of coexpression of maspin with p63 and p53 in squamous cell carcinoma but not in adenocarcinoma of the lung

Original Article High frequency of coexpression of maspin with p63 and p53 in squamous cell carcinoma but not in adenocarcinoma of the lung

... of maspin [18], particularly in lung tumorigenesis ...p63 expression was not seen in normal lung tissue, it has been observed in normal bronchial tissue with geno- mic amplification in the development of ...

6

Maspin enhances cisplatin chemosensitivity in bladder cancer T24 and 5637 cells and correlates with prognosis of muscle-invasive bladder cancer patients receiving cisplatin based neoadjuvant chemotherapy

Maspin enhances cisplatin chemosensitivity in bladder cancer T24 and 5637 cells and correlates with prognosis of muscle-invasive bladder cancer patients receiving cisplatin based neoadjuvant chemotherapy

... increase Maspin expression ...the expression of maspin, such as artificial transcription factors (ATFs) and chromatin remodeling drugs ...reactivate Maspin expression and in- ...

11

Maspin is a deoxycholate-inducible, anti-apoptotic stress-response protein differentially expressed during colon carcinogenesis

Maspin is a deoxycholate-inducible, anti-apoptotic stress-response protein differentially expressed during colon carcinogenesis

... Increased maspin expression in the colon is related to colon cancer risk and patient ...survival. Maspin is induced by the hydrophobic bile acid, deoxycholate (DOC), which is an endogenous carcinogen ...

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Maspin plays an essential role in early embryonic development

Maspin plays an essential role in early embryonic development

... a maspin genomic clone from the mouse 129/sv genomic ...of maspin is located in exon 6. To generate a mutant lacking maspin function, murine 129 embryonic stem (ES) cells were transfected with a ...

11

Mapsin  Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma

Mapsin Expression in Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma

... positive maspin expression with different degrees of intensity and ...that maspin expression in these tumors coincides with their biological ...

8

Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis

Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis

... Ets-1 expression was much stronger in ovarian cancer than benign tumors; it had no significant correlation with other biological behaviors, such as grade, stage and ...and maspin expression showed no ...

6

Maspin and MCM2 immunoprofiling in salivary gland carcinomas

Maspin and MCM2 immunoprofiling in salivary gland carcinomas

... the expression of maspin ...induce maspin expression in vitro and in situ ...that maspin has an inhibitory effect on tumor induced angiogenesis [14], cell motility, invasion and ...

8

miRNA-7/21/107 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin

miRNA-7/21/107 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin

... of maspin expression in HCC patients was first ...lower maspin mRNA level (Figure 1A) and 24 of 32 cases ...lower maspin protein level (Supplemental Figure S1A). The ratio of maspin ...

13

Original Article Relationship of endothelial area with VEGF-A, COX-2, maspin, c-KIT, and DOG-1 immunoreactivity in liposarcomas versus non-lipomatous soft tissue tumors

Original Article Relationship of endothelial area with VEGF-A, COX-2, maspin, c-KIT, and DOG-1 immunoreactivity in liposarcomas versus non-lipomatous soft tissue tumors

... CD34, maspin, DOG-1, and ...VEGF, maspin, and ...role. Maspin expression was observed in adipose tissue tumors ...and maspin positivity in liposarcomas have been published to ...

7

Role of maspin in cancer

Role of maspin in cancer

... Its expression is down-regulated in breast, prostate, gastric and melanoma cancers but over-expressed in pancreatic, gallbladder, colorectal, and thyroid cancers suggesting that maspin may play different ...

19

Unexpected maspin immunoreactivity in Merkel cell carcinoma

Unexpected maspin immunoreactivity in Merkel cell carcinoma

... skin, maspin immunoreactivity was de- scribed in 97 % of squamous cell carcinomas and 88 % of basal cell carcinomas, but also in malignant melanomas, more frequent in sun-exposed areas [32, ...regarding ...

6

Digital expression analysis of the genes associated with salinity resistance after overexpression of a stress-responsive small GTP-binding RabG protein in peanut.

Digital expression analysis of the genes associated with salinity resistance after overexpression of a stress-responsive small GTP-binding RabG protein in peanut.

... In our previous study, we isolated an important small GTP-binding protein from peanut; this protein was found to be responsive to different stress treatments and plant hormone ABA, and exhibited enhanced tolerance to ...

12

Expression of catalase, alcohol dehydrogenase, and malate dehydrogenase in rot grains upon fungicide use on maize hybrids grown at different spacings.

Expression of catalase, alcohol dehydrogenase, and malate dehydrogenase in rot grains upon fungicide use on maize hybrids grown at different spacings.

... the expression of the ADH enzyme was determined for all hybrids and all treatments evaluated in environment 2 in the crop of ...higher expression of the ADH enzyme was observed for the hybrids belonging to ...

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