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Medicinal Plants, Drug Discovery, Metabolism

Application of metabolomics to drug discovery and understanding the mechanisms of action of medicinal plants with anti-tuberculosis activity

Application of metabolomics to drug discovery and understanding the mechanisms of action of medicinal plants with anti-tuberculosis activity

... distribution, metabolism, excretion, and toxicity; ATP: adenosine triphosphate; CCM: central carbon metabolism; CE–MS: capillary electrophoresis mass spectrometry; ClpP: cutinase‑like protein proteases; CS: ...

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Plant Secondary Metabolites of Antiviral Properties a Rich Medicinal Source for Drug Discovery: A Mini Review

Plant Secondary Metabolites of Antiviral Properties a Rich Medicinal Source for Drug Discovery: A Mini Review

... secondary metabolism (Lattanzio, ...in plants defense mechanism either directly or indirectly to protect plants from insects through repellence, inducing toxicity and growth inhibition of competitive ...

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Medicinal plant genome: a source of finding new enzymes,  metabolic pathways and drug discovery

Medicinal plant genome: a source of finding new enzymes, metabolic pathways and drug discovery

... significant medicinal value, and the plant contains various therapeutically important alkaloids, flavonoids and phenolics and has got bioactivities against cancer, ulcer, and various microbes (Yang et ...sugar ...

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Naturally Derived Formulations and Prospects towards Cancer

Naturally Derived Formulations and Prospects towards Cancer

... and medicinal plants are known to possess antioxidant ...[1]. Drug development is an essential part of research owing to low bio-availability of flavonoids and their lack of stability, excessive ...

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Compounds from African Medicinal Plants with Activities against Protozoal Diseases: Schistosomiasis, Trypanosomiasis and Leishmaniasis

Compounds from African Medicinal Plants with Activities against Protozoal Diseases: Schistosomiasis, Trypanosomiasis and Leishmaniasis

... lead drug discovery research groups into reasonable starting points for further development of fast, effective and affordable novel molecules for the treatment of parasitic ...diseases. Drug ...

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 MEDICINAL PLANTS USED AS AN ANTIDIABETIC DRUG IN PHARMACEUTICAL INDUSTRY AND THEIR CONSERVATION: AN OVERVIEW

 MEDICINAL PLANTS USED AS AN ANTIDIABETIC DRUG IN PHARMACEUTICAL INDUSTRY AND THEIR CONSERVATION: AN OVERVIEW

... Antidiabetic plants for pharmaceutical ...different plants using in the traditional system for the treatment of diabetes since ancient ...times. Plants such as Allium cepa, Anacardium occidentale, ...

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CamMedNP: Building the Cameroonian 3D structural natural products database for virtual screening

CamMedNP: Building the Cameroonian 3D structural natural products database for virtual screening

... Cameroonian medicinal plants for the very first ...from plants of the Leguminosae family ...that plants of the Leguminosae family (Crotalaria ...

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Approach to Phytochemistry and Mechaniasm of Action of Plants having Antidiabetic Activity

Approach to Phytochemistry and Mechaniasm of Action of Plants having Antidiabetic Activity

... native medicinal plants with confirmed blood sugar lowering ...Indian plants with their phytoconstituents and mechanism of action which have been studied for their antidiabetic ...

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CVDHD: a cardiovascular disease herbal database for drug discovery and network pharmacology

CVDHD: a cardiovascular disease herbal database for drug discovery and network pharmacology

... There were two main groups of target proteins in CVDHD. One was the drug targets retrieved from Drug- Bank [28], another was the other proteins of human. Each protein had X-ray or NMR ligand-protein complex ...

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Directing the Metabolism of Drugs Away  from CYP450: The Use of Oxetane Rings

Directing the Metabolism of Drugs Away from CYP450: The Use of Oxetane Rings

... to drug discovery, a large fraction of healthcare includes pharmacothera- ...other drug metabolizing ...CYP450 drug metabolism could have a significant ...

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Ayurvedic Drugs Used In Eye  Disorder-A Review

Ayurvedic Drugs Used In Eye Disorder-A Review

... As the Panchkarma is the bases of Kayachikitsha, Kriyakalpa is the main therapeutic process for Ophthalmology in Shalakya tantra. The word Kriyakalp built from two words: Kriya and Kalpa. Kriya means therapeutic ...

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Assessment of Traditional Medicinal Plants Used for Treatment of Human Diseases in Oromia Region, West Shewa Zone: Jeldu Woreda, Ethiopia

Assessment of Traditional Medicinal Plants Used for Treatment of Human Diseases in Oromia Region, West Shewa Zone: Jeldu Woreda, Ethiopia

... regarding medicinal plants was collected from available vendors of medicinal plants in Jeldu ...Many plants are being used to treat both skin condition as well as stomach ...the ...

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Studies on the Leaves of Solanum Melongena Var.Melongena
and its Promising Ace Inhibition for Various Therapeutic
Approaches

Studies on the Leaves of Solanum Melongena Var.Melongena and its Promising Ace Inhibition for Various Therapeutic Approaches

... based. Medicinal plants usually have multiple Phyto- constituents to act synergistically act with various targets, have better bio-availability and ...

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SYNTHESIS AND BIOLOGICAL SCREENING OF BENZIMIDAZOLE DERIVATIVES

SYNTHESIS AND BIOLOGICAL SCREENING OF BENZIMIDAZOLE DERIVATIVES

... 1. Analgesic activity: Writhing test were performed for analgesic activity. Mice of either sex with a weight between 20 and 25g were used. Group of 6 animals are used for controls and treated mice. Preferably, two groups ...

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Medico - Botanical studies of angiosperms from select areas of Agastheeswaram Taluk in Kanyakumari District, Tamilnadu, Southern India

Medico - Botanical studies of angiosperms from select areas of Agastheeswaram Taluk in Kanyakumari District, Tamilnadu, Southern India

... However, Ethnomedicine is specifically referred to as the study of traditional medical practice which is concerned with the cultural interpretation of health, diseases and illness and also addresses the healthcare ...

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Indigenous Medicinal Plants of Village Mithakhel, District Karak, Pakistan

Indigenous Medicinal Plants of Village Mithakhel, District Karak, Pakistan

... For proper guidance and collection of plants map of Mithakhel was obtained from concerned office. A proforma was design to explore the medicinal plants of study area. i: e name of plant, ...

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Pharmacognostical Evaluation of Annona squamosa Linn: Original article

Pharmacognostical Evaluation of Annona squamosa Linn: Original article

... As there is no pharmacognostical anatomical work on records for this traditionally valued herb, the present study is taken up in the view to lay down the physico-chemical and microscopic standards. Microscopical and ...

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Assessment of Bioactivity of Desmostachya Bipinnata (L.) Stapf  Using Brine Shrimp (Artemia Salina) Lethality Assay

Assessment of Bioactivity of Desmostachya Bipinnata (L.) Stapf Using Brine Shrimp (Artemia Salina) Lethality Assay

... alternative medicinal systems of India ...such medicinal compounds have been discovered with the aid of ethno-botanical knowledge of their traditional ...in medicinal plants and health care ...

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Article -   DOCUMENTA TION OF ETHNO-MEDICI NAL PLANTS USED BY SOLIGA TRIBE OF BILIGIRIRANGANA HILLS OF CHAMARAJANAGARA DIS TRICT

Article - DOCUMENTA TION OF ETHNO-MEDICI NAL PLANTS USED BY SOLIGA TRIBE OF BILIGIRIRANGANA HILLS OF CHAMARAJANAGARA DIS TRICT

... ethno-medicinal plants used by Soliga tribes of Biligirirangana ...healing plants by the rich knowledge accumulated in unlettered ...ethno medicinal plants used by the Soliga tribes, ...

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Diversity oriented natural product platform identifies plant constituents targeting Plasmodium falciparum

Diversity oriented natural product platform identifies plant constituents targeting Plasmodium falciparum

... for drug development, especially for the treatment of malaria ...the discovery process, citing several exam- ples from plants as supporting evidence ...

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