Membrane microdomains (rafts)
Multimerization of Human Immunodeficiency Virus Type 1 Gag Promotes Its Localization to Barges, Raft-Like Membrane Microdomains
... for rafts in the HIV-1 life ...of rafts, namely, a marked enrichment in sphin- gomyelin and cholesterol with respect to the plasma membrane of host cells, as well as a fluidity suggestive of a lipid ...
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West Nile Virus Entry Requires Cholesterol-Rich Membrane Microdomains and Is Independent of αvβ3 Integrin
... lipid rafts are also required for WNV ...lipid rafts for entry (DENV, hepatitis C virus [HCV], and bovine viral diarrhea virus) or replication (Kunjin virus and HCV) (1, 17, 18, 21, ...plasma ...
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Heterogeneity of Raft-Type Membrane Microdomains Associated with VP4, the Rotavirus Spike Protein, in Caco-2 and MA 104 Cells
... raft-type membrane microdomains (RTM) in Caco-2 cells provided a simple expla- nation for rotavirus polarized ...with rafts is not sufficient to explain its apical targeting in intestinal ...with ...
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Pseudotypes of Vesicular Stomatitis Virus with CD4 Formed by Clustering of Membrane Microdomains during Budding
... CD4-containing microdomains are similar in ...lipid rafts, this raised the question of whether CD4 was organized into mem- brane microdomains in BHK cells or whether it was distributed randomly in ...
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Human Immunodeficiency Virus Type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains
... additional membrane targeting motifs, a subpopulation of Nef resides in detergent resist- ant membrane microdomains (DRMs) or lipid rafts [18- ...Lipid rafts are defined as highly ...
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Plasma Membrane Microdomains Containing Vesicular Stomatitis Virus M Protein Are Separate from Microdomains Containing G Protein and Nucleocapsids
... 100-nm membrane microdomains (Fig. 2) and that M protein microdomains are formed in the absence of other VSV components ...protein microdomains is consistent with previous data on the interac- ...
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Assembly of Arenavirus Envelope Glycoprotein GPC in Detergent-Soluble Membrane Microdomains
... membrane microdomains. Because the size of typical mem- brane microdomains is at or below the limit of resolution of confocal microscopy ( ⬍ 200 nm), we further analyzed the dis- tribution of GPC on ...
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Alteration of actin dependent signaling pathways associated with membrane microdomains in hyperlipidemia
... Detergent resistant membrane microdomains isolation DRM microdomains fractions were prepared as previ- ously described [18]. Briefly, 200 mg of lung tissue fragments were solubilized on ice in 1.8 ml ...
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Coronavirus and Influenza Virus Proteolytic Priming Takes Place in Tetraspanin-Enriched Membrane Microdomains
... TEMs contain coronavirus receptors and priming proteases. Our findings fit with the hypothesis that infecting viruses encoun- ter cell receptors and priming proteases at TEM locations. Anti- body binding to TEMs, or ...
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Virus Particle Release from Glycosphingolipid-Enriched Microdomains Is Essential for Dendritic Cell-Mediated Capture and Transfer of HIV-1 and Henipavirus
... plasma membrane lipid rafts to an extent similar to that exhibited by HIV-1 ...plasma membrane microdomains ...lipid microdomains as a plat- form for virus assembly and budding ...
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Diet-induced hypercholesterolemia promotes androgen- independent prostate cancer metastasis via IQGAP1 and caveolin-1
... cholesterol membrane microdomains (Figure ...rich membrane domains. While IQGAP1 membrane targeting is essential for its regulation of migration, to our knowledge, this is the first report of ...
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Gag Induces the Coalescence of Clustered Lipid Rafts and Tetraspanin-Enriched Microdomains at HIV-1 Assembly Sites on the Plasma Membrane
... general membrane phenomenon underlies this coalescence of microdomains—a property or function of the membrane that Gag derivatives can affect regardless of membrane binding ...for ...
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The cytosolic N-terminus of CD317/tetherin is a membrane microdomain exclusion motif.
... that membrane microdomain localisation of CD317 is not dependent upon protein dimerisation or the presence of the amino terminal cytosolic domain (Billcliff et ...into membrane microdomains, and ...
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Insulin Signaling in Microdomains of the Plasma Membrane
... A potential clue towards identifying the PI 3-kinase- independent arm of insulin action emerged from the idea that signal initiation might be segregated into discrete compartments in the plasma membrane. One ...
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Plasma membrane rafts of rainbow trout are subject to thermal acclimation
... Membrane molecular interaction strength also influences the detergent/lipid values necessary to disrupt bilayer morphology and incorporate membrane molecules into mixed micelles (solubilization slopes). For ...
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The Nascent Parasitophorous Vacuole Membrane of Encephalitozoon cuniculi Is Formed by Host Cell Lipids and Contains Pores Which Allow Nutrient Uptake
... PV membrane is immediately formed during entry of the ...PV membrane formation on viable, DiIC 16 -labeled human fibroblasts by time- lapse fluorescence ...PV membrane after extru- sion, ...
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Role of Cholesterol in Human Immunodeficiency Virus Type 1 Envelope Protein-Mediated Fusion with Host Cells
... Preparation of detergent-resistant membrane (DRM) fractions. Plasma mem- brane rafts were obtained as previously described (52). Briefly, primary lympho- cytes were left untreated at 37°C or incubated with ...
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Oral Delivery of Protein Drugs: Driver for Personalized Medicine?
... plasma membrane lipid rafts to cytoplasmic lipid droplets trigger their subsequent translocation from the lipid droplets into membranes of small vesicles, which then leave the ...
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Cholesterol modification of Hedgehog family proteins
... clear whether this is a direct effect, or an indirect effect due to the possible facilitation of the second modifica- tion, palmitoylation (14, 20). Palmitoylation occurs at the N-terminus of the mature signaling domain ...
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Cholesterol-Rich Microdomains as Docking Platforms for Respiratory Syncytial Virus in Normal Human Bronchial Epithelial Cells
... in all experiments. All images have been merged. An arrow indicates the time dependence of the color shift of a dually labeled virion from red (nonfused) through yellow to the disappearance of the DiOC18 fluorescence ...
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