Mesial temporal lobe epilepsy
Mesial temporal lobe epilepsy with psychiatric comorbidities: a place for differential neuroinflammatory interplay
... Mesial temporal lobe epilepsy (MTLE) is the most common cause of intractable epilepsy in adults and is characterized by hippocampal sclerosis, neuronal loss, gliosis, and mossy fiber ...
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In Vivo Mapping of Hippocampal Subfields in Mesial Temporal Lobe Epilepsy: Relation to Histopathology
... The human hippocampus is composed of a complex and heterogeneous structure. However, the hippocampus is usually modelled as a single structure in neuroimaging research; this is particularly due to the insufficient ...
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Neurotrophin receptors expression in mesial temporal lobe epilepsy with and without psychiatric comorbidities and their relation with seizure type and surgical outcome
... in mesial temporal lobe epilepsy (MTLE) patients with psychiatric ...from epilepsy surgery, and control necropsies were investigated for p75 NTR , TrkB, TrkA, and TrkC ...
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Influence of Resting State Network on Lateralization of Functional Connectivity in Mesial Temporal Lobe Epilepsy
... on epilepsy have focused on the epileptogenic zone, epilepsy is a system-level disease characterized by aberrant neuronal synchronization among groups of ...that mesial temporal lobe ...
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Hippocampal Atrophy Is Associated with Altered Hippocampus–Posterior Cingulate Cortex Connectivity in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis
... MATERIALS AND METHODS: Fifteen patients with left mesial temporal lobe epilepsy with hippocampal sclerosis and 15 healthy controls were included in the study. Multicontrast MR imaging, ...
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Time Shift Homotopic Connectivity in Mesial Temporal Lobe Epilepsy
... MATERIALS AND METHODS: Resting-state functional MR imaging data were acquired from patients with unilateral mesial temporal lobe epilepsy (n ⫽ 62) (31 left- and 31 right-side) and healthy ...
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Relationship between remnant hippocampus and amygdala and memory outcomes after stereotactic surgery for mesial temporal lobe epilepsy
... purpose: Mesial temporal structures play an important role in human ...In mesial temporal lobe epilepsy (MTLE), seizure activity is generated from the same ...standard ...
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Rare variants and de novo variants in mesial temporal lobe epilepsy with hippocampal sclerosis
... Mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS) is among the most drug-resistant types of focal ...surrounding mesial temporal structures can be an ...
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Original Article Differential long non-coding RNA (lncRNA) profiles associated with hippocampal sclerosis in human mesial temporal lobe epilepsy
... human mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS) and to detect the functions of ln- cRNAs in epileptogenesis in ...
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Brain region and epilepsy-associated differences in inflammatory mediator levels in medically refractory mesial temporal lobe epilepsy
... AED: Antiepileptic drug; ANOVA: Analysis of variance; BBB: Blood-brain barrier; CHI: Moderate-to-severe closed head injury; CNS: Central nervous system; CRP: C- reactive protein; CSF: Cerebral spinal fluid; EDTA: ...
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Resting-state Functional Network Disruptions in a Rodent Model of Mesial Temporal Lobe Epilepsy (TLE)
... tions (BOLD signal) rooted in the neuronal and synaptic activity that reflects stimulus-independent processing in the brain as opposed to an external stimulus (Kandel, Schwartz, & Jessell, 2012). Func- tional ...
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Multisection Proton MR Spectroscopy for Mesial Temporal Lobe Epilepsy
... than mesial hypometabolism in cases of mTLE ...successful epilepsy surgery (32) suggest transient neuronal metabolic impairment due to ...the temporal section beyond the hippocampus displaying 兩NAA兩 ...
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3T MRI Quantification of Hippocampal Volume and Signal in Mesial Temporal Lobe Epilepsy Improves Detection of Hippocampal Sclerosis
... by epilepsy imaging ...specific epilepsy protocols have improved the visual detection of MR imaging signs of HS, the use of techniques to measure the abnormal hippocampal volume and T2 signal can still ...
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Correlation of neuropsychological and metabolic changes after epilepsy surgery in patients with left mesial temporal lobe epilepsy with hippocampal sclerosis
... frontal lobe and represented a seizure-related dynamic process in view of further ictal perfusion decreases ...frontal lobe is a dynamic defense mechanism against seizure propagation and may be responsible ...
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Temporal Cortex Morphology in Mesial Temporal Lobe Epilepsy Patients and Their Asymptomatic Siblings
... of epilepsy, suggesting a role for genetic factors in the contri- bution to hippocampal abnormalities (Fernandez et ...These temporal re- gions are anatomically connected to the hippocampus, and often they ...
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Practice parameter: Temporal lobe and localized neocortical resections for epilepsyReport of the Quality Standards Subcommittee of the American Academy of Neurology, in Association with the American Epilepsy Society and the American Association of Neurological Surgeons
... anteromesial temporal lobe and localized neocor- tical resections for disabling complex partial seizures by systematic review and analysis of the literature since ...for mesial temporal ...
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Clinical spectrum of STX1B-related epileptic disorders
... as a genetic risk factor 33 ), and at least one GEFS+ multiplex family with mesial temporal lobe epilepsy has been reported. 34 Of interest is our patient with episodes reminiscent of hemi- ...
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Depressive disorders in patients with epilepsy: Why should neurologists care?
... of temporal- and ...cortex, temporal, lateral neocortex, as well as of the prefrontal, orbitofrontal, and mesial-frontal cortex, and to a lesser degree, of the tha- lamic nuclei and basal ganglia ...
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Temporal Lobe Epilepsy With Hippocampal Sclerosis in Acute Lymphoblastic Leukemia
... developed mesial temporal lobe epilepsy with hippocampal sclerosis ...typical temporal spikes on EEG, and hippocampal sclerosis ...
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UNSUPERVISED CLASSIFICATION OF HIGH-FREQUENCY OSCILLATIONS IN NEOCORTICAL EPILEPSY AND CONTROL PATIENTS
... the epilepsy research community began against the backdrop discussed above, in large part with the work of Bragin et ...human epilepsy patients, primarily in association with seizures [2, 30], Bragin was ...
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