Mesoporous silica nanoparticles
Mesoporous silica nanoparticles as a compound delivery system in zebrafish embryos
... Figure 3 Toxicity of mesoporous silica nanoparticles (MSNPs). (A) Graph showing percentage mortality in zebrafish larvae, larvae affected by pericardial edema, or larvae with normal morphology. The ...
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Study of Mesoporous Silica Nanoparticles as Nanocarriers for Sustained Release of Curcumin
... Cationic nanoparticles of chitosan/poly (ε-caprolactone) nanoparticles loaded by CUR were prepared and enhanced the cellular uptake of CUR ...[10]. Mesoporous silica nanoparticles (MSN) ...
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Functionalized Mesoporous Silica Nanoparticles as a Novel Antioxidant Delivery System
... circulation. Mesoporous silica nanoparticles (MSNs) have been widely used as a carrier for therapeutic applications because of their suitable biological ...Synthesized nanoparticles were ...
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Interaction of Mesoporous Silica Nanoparticles with Human Red Blood Cell Membranes: Size and Surface Effects
... of mesoporous silica nanoparticles (MSNs) of different particle sizes and surface properties with human red blood cell (RBC) membranes were investigated by membrane filtration, flow cytometry, and ...
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Hollow mesoporous silica nanoparticles for intracellular delivery of fluorescent dye
... the nanoparticles and a progressive increase in fluorescence emitted by nanoparticle-labelled cells was observed with increased in time ...that nanoparticles uptake by Hela cells was significantly higher at ...
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Effect of Paclitaxel Mesoporous Silica Nanoparticles with a Core Shell Structure on the Human Lung Cancer Cell Line A549
... paclitaxel-mesoporous silica nanoparticles with a core-shell structure (PAC-csMSN) was used to increase the dissolution of paclitaxel (PAC) and improve its treatment of lung ...core-shell ...
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Redox/pH dual-controlled release of chlorhexidine and silver ions from biodegradable mesoporous silica nanoparticles against oral biofilms
... Considering this, the goal of the present study was to investigate whether these biodegradable nanoantiseptics could achieve the redox/pH dual-controlled release of CHX and silver ions against S. mutans biofilms (Figure ...
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Liver cancer cells: targeting and prolonged-release drug carriers consisting of mesoporous silica nanoparticles and alginate microspheres
... inorganic mesoporous silica nanoparticles (MSNs) and organic alginate (denoted as MSN@Alg) was successfully synthesized by air-dynamic atomization and applied to the intracellular drug delivery ...
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Polyaspartic acid-anchored mesoporous silica nanoparticles for pH-responsive doxorubicin release
... in drug delivery applications on account of their facility to improve solubility of less water- soluble drugs, control drug pharmacokinetics, increase drug half-life through decreasing immunogenicity, increase ...
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Development of an oral push–pull osmotic pump of fenofibrate-loaded mesoporous silica nanoparticles
... Abstract: In this study, mesoporous silica nanoparticles (MSNs) were used to prepare an oral push–pull osmotic pump. Fenofibrate, the selected model drug, was firstly loaded into the MSNs, followed ...
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Catalyzed Schiff Base synthesis over Bifunctinalized Cobalt/Zinc-Incorporated Mesoporous Silica Nanoparticles under UV irradiation
... Mesoporous silica nanoparticles (denoted by MSN) was synthesized by the sol-gel method in the basic conditions [9]. Typically, Cetyltrimethylammonium bromide (CTAB, 1.17 g) was dissolved in a ...
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Meyer-Schwickerath, Charlotte (2019): Validation of CCR2-targeted mesoporous silica nanoparticles for lung cancer therapy. Dissertation, LMU München: Medizinische Fakultät
... Lung cancer has one of the highest mortality rates of all cancers world-wide and as common chemotherapeutics fail to provide a promising effect, recent research has focused on new targeted therapeutic agents, which have ...
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In vitro release and in vitro–in vivo correlation for silybin meglumine incorporated into hollow-type mesoporous silica nanoparticles
... hollow-type mesoporous silica nanoparticles (HMSNs) were prepared and used as an in vitro sustained drug-release model for water-soluble ...of mesoporous silica nanoparticles, ...
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Mesoporous silica nanoparticles as delivery system against diseases
... Nowadays, mesoporous silica nanoparticles (MSNPs) have emerged as promising candidate because they can overcome all the barriers maximally by producing their biological effectiveness in a controlled ...
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Label-Free Luminescent Mesoporous Silica Nanoparticles for Imaging and Drug Delivery
... Mesoporous silica nanoparticles, due to their low toxicity and high loading capacity, have been widely used as a drug delivery vehicle ...onto mesoporous silica nanoparti- cles and ...
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<p>Improving Solubility and Bioavailability of Breviscapine with Mesoporous Silica Nanoparticles Prepared Using Ultrasound-Assisted Solution-Enhanced Dispersion by Supercritical Fluids Method</p>
... Various methods have been developed to solve the formu- lation challenges of insoluble drugs, such as ultra fi ne grinding, 7 nanocrystal techniques, 8 lipid-based formulation, 9 solid dispersions 10 and so on. With the ...
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Delivering hydrophilic and hydrophobic chemotherapeutics simultaneously by magnetic mesoporous silica nanoparticles to inhibit cancer cells
... Using nanoparticles to deliver chemotherapeutics offers new opportunities for cancer therapy, but challenges still remain when they are used for the delivery of multiple drugs, especially for the synchronous ...
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<p>Antibacterial Activity of a Novel Biocomposite Chitosan/Graphite Based on Zinc-Grafted Mesoporous Silica Nanoparticles</p>
... Zn-MSN nanoparticles and CGZM-bio were ...Zn-MSN nanoparticles and CGZM-bio were sterilized by dropping ethanol onto these materials and aging for 10 mins, then placed on the surface of MH which was seeded ...
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The comparative immunotoxicity of mesoporous silica nanoparticles and colloidal silica nanoparticles in mice
... We compared the immunotoxicity of MPS and Col NPs in mice to examine the effects of pore structure conditions of silica NPs. MPS NPs increased spleen weight and splenocyte proliferation. Mice treated with MPS NPs ...
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<p>Hyaluronic acid-modified mesoporous silica-coated superparamagnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles for targeted drug delivery</p>
... ed mesoporous silica nanoparticles (MSNs-SS-HA) increased the drug release in the targeted sites, and this was attributed to the high GSH concentration in the cancer ...
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