messenger RNA (mRNA)
Defects in DNA and globin messenger RNA in homozygotes for hemoglobin Lepore
... Globin messenger RNA mRNA isolated from three patients homozygous for hemoglobin Lepore is shown to have a marked reduction of the amount of beta-like globin mRNA Lepore-globin mRNA sequ[r] ...
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Modulation of proinsulin messenger RNA after partial pancreatectomy in rats Relationships to glucose homeostasis
... Abstract These studies of partial pancreatectomy assess pancreatic proinsulin messenger RNA mRNA levels as an index of in vivo insulin biosynthesis, and show relationships to glucose hom[r] ...
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Distribution of glucose transporter messenger RNA transcripts in tissues of rat and man
... We used the complementary DNA for the human hepatoma Hep G2 glucose transporter to determine the distribution of glucose transporter messenger RNA (mRNA) in rat and human tissues. Under stringent ...
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Studies on the Isolation of Messenger RNA
... STUDIES ON THE ISOLATION OF MESSENGER RNA Thesis by '' , ('\ ,, ALEXANDER LYON In Partial Fulfillment of the Requirements For the Degree of Doctor of Philosophy California Institute of Technology Pasa[.] ...
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Defect in messenger RNA for human hemoglobin synthesis in beta thalassemia
... The messenger RNA stimulated the synthesis of human globin chains by a cell-free system derived from Krebs mouse ascites ...thalassemia messenger RNA, the system synthesized much less beta ...
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RNA Sequencing Analysis of Messenger RNA/MicroRNA in a Rabbit Aneurysm Model Identifies Pathways and Genes of Interest
... rabbit RNA database was used for messenger RNA expression, whereas human databases were used for miRNA because a rabbit miRNA database is not ...The RNA collected was not from a single cell ...
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Messenger RNA reprogramming by spliceosome mediated RNA trans splicing
... The structure of human genes and primary transcripts. A schemat- ic of a gene (DNA), its primary transcript (pre-mRNA), and the mature mRNA product. The gene in this schematic spans four exons (boxes 1 through 4) and ...
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Killing The Messenger: Exploring Novel Triggers For Messenger Rna Decay In Eukaryotes
... of messenger RNAs is regulated by multiple layers beyond their primary ...with RNA binding proteins, marked with covalent chemical modifications, and fold into intricate secondary ...of RNA secondary ...
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Posttranscriptional defects in beta globin messenger RNA metabolism in beta thalassemia: abnormal accumulation of beta messenger RNA precursor sequences
... produced normal amounts of globin alpha and beta [3H]mRNA during a 20-min pulse incubation, but the beta/alpha [3H]mRNA ratio declined to steady-state levels during a chase incubation, suggesting posttranscriptional ...
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Developmental and hormonal regulation of glucocorticoid receptor messenger RNA in the rat
... To study the developmental tissue-specific regulation of the GR, we measured the relative concentration of GR mRNA in fetal, neonatal, adult, and aged rats and examined the effects of de[r] ...
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The Effects of Fasting and Feeding on Preproinsulin Messenger RNA in Rats
... preproinsulin messenger (m)RNA activity could account for changes in insulin biosynthesis during fasting and ...Islet RNA decreased to 50% and protein to 55% that of control animals, while islet DNA ...
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Analysis of proteins bound to stored messenger RNA in 'Xenopus' oocytes
... Different forms of soluble cytoplasmic mRNA binding proteins and particles in Xenopus laevis oocytes and embryos.. Sequence analysis of cytoplasmic mLNA-binding proteins of Xenopus oocyt[r] ...
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Androgen regulation of rat renal angiotensinogen messenger RNA expression
... Northern and slot blot analyses with alpha-32P labeled ang-n cDNA pRang 3 demonstrated that castration lowered ang-n mRNA levels in the male kidney by greater than or equal to 60% compar[r] ...
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Expression and localization of gastrin messenger RNA and peptide in spermatogenic cells
... Similarly, in situ hybridization experiments revealed no labeling over sections from monkey testis using the human gastrin-specific oligonucleotide, whereas an oligonucleotide specific f[r] ...
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Full length messenger RNA sequences greatly improve genome annotation
... The alignments generated from the cDNA sequences were used to create new gene models for the corresponding genes in the A. thaliana genome. Many of the genes have been manually curated, but many others were created by ...
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Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β
... Background Matrix metalloproteinases are catabolic enzymes that play a key role in the articular cartilage degeneration evident in degenerative and inflammatory conditions of articular cartilage. The aim of this study is ...
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Structural Units of Reovirus Ribonucleic Acid and Their Possible Functional Significance
... Further, the singlestranded RNA ssRNA formed in infected cells 10, 17 and shown to be largely messenger RNA mRNA transcribed from the viral genome 14, 17 has been separated into three fr[r] ...
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Altered proopiomelanocortin gene expression in adrenocorticotropin producing nonpituitary tumors Comparative studies with corticotropic adenomas and normal pituitaries
... In order to assess the mechanisms of proopiomelanocortin (POMC) gene expression in human ACTH-producing tumors, we performed the simultaneous evaluation of POMC products and messenger RNA (mRNA) in tissue ...
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Study of the molecular mechanism of decreased liver synthesis of albumin in inflammation
... decreased synthesis could not be related to a reduced amino acid supply, we have also examined the possible molecular mechanisms of reduced albumin synthesis during inflammation using in vivo and in vitro experiments in ...
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RNA thermosensors: how might animals exploit their regulatory potential?
... of RNA structure are crucial for a suite of RNA-related functions, including regulation of translation, gene expression and RNA ...of RNA secondary and tertiary structures is exploited by ...
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