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Metabolic Acidosis

Chronic metabolic acidosis decreases albumin synthesis and induces negative nitrogen balance in humans

Chronic metabolic acidosis decreases albumin synthesis and induces negative nitrogen balance in humans

... Chronic metabolic acidosis has been previously shown to stimulate protein ...chronic metabolic acidosis on nitrogen balance and protein synthesis we measured albumin synthesis rates and ...

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Respiratory and metabolic acidosis correction with the ADVanced Organ Support system

Respiratory and metabolic acidosis correction with the ADVanced Organ Support system

... and metabolic acidosis are associated with poor outcome in cirrhosis patients, as demonstrated by Drolz and colleagues in a cohort of 178 critically ill patients with liver cirrhosis and acute on chronic ...

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A rare cause of metabolic acidosis: ketoacidosis in a non-diabetic lactating woman

A rare cause of metabolic acidosis: ketoacidosis in a non-diabetic lactating woman

... increased metabolic demands during lactation, reduction in carbohydrate intake and acute ...severe metabolic acidosis on admission with a blood 3-hydroxybutyrate of ...

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Metabolic acidosis and the progression of chronic kidney disease

Metabolic acidosis and the progression of chronic kidney disease

... chronic metabolic acidosis could slow the progression of ...of acidosis? Higher serum bicarbonate was associated with increased risk of congestive heart failure in the CRIC study [14], but to date ...

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Glucose Utilization and Production by the Dog Kidney In Vivo in Metabolic Acidosis and Alkalosis

Glucose Utilization and Production by the Dog Kidney In Vivo in Metabolic Acidosis and Alkalosis

... Using D-[1- 14 C]glucose as a tracer, renal glucose utilization and production was measured in chronic metabolic acidosis and alkalosis in dog kidney in vivo. In six experiments in acidosis, mean ...

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Ammonia production by isolated mouse proximal tubules perfused in vitro  Effect of metabolic acidosis

Ammonia production by isolated mouse proximal tubules perfused in vitro Effect of metabolic acidosis

... of metabolic acidosis in vivo and reduced bath and luminal pH in vitro on total NH3 (NH3 + NH+4) production rates by isolated mouse proximal tubule ...NH4Cl-induced metabolic acidosis and from ...

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Renal ammoniagenesis in an early stage of metabolic acidosis in man

Renal ammoniagenesis in an early stage of metabolic acidosis in man

... the acidosis, the greater was the renal extraction of these amino acids (P less than ...of metabolic acidosis, in spite of a brisk increase in ammonia production, the mechanisms responsible for the ...

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Physiological and molecular responses of the goldfish (Carassius auratus) kidney to metabolic acidosis, and potential mechanisms of renal ammonia transport

Physiological and molecular responses of the goldfish (Carassius auratus) kidney to metabolic acidosis, and potential mechanisms of renal ammonia transport

... The almost 2-fold increase in plasma cortisol in acid-exposed goldfish (Table 1) may have promoted renal ammoniogenesis by augmenting the supply of amino acids through a stimulation of proteolysis (Milligan, 1997; ...

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Acute metabolic acidosis enhances circulating parathyroid hormone, which contributes to the renal response against acidosis in the rat

Acute metabolic acidosis enhances circulating parathyroid hormone, which contributes to the renal response against acidosis in the rat

... acute metabolic acidosis enhances circulating PTH activity, and (b) PTH markedly contributes to the renal response against acute metabolic acidosis by enhancing urinary ...

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Changes in bone sodium and carbonate in metabolic acidosis and alkalosis in the dog

Changes in bone sodium and carbonate in metabolic acidosis and alkalosis in the dog

... Metabolic acidosis and alkalosis were produced in adult dogs over 5- to 10-day periods. Midtibial cortical bone was analyzed for calcium, sodium, phosphorus, and carbonate. In acidosis bone CO 3 /Ca ...

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Chronic metabolic acidosis enhances NHE 3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE 3 mRNA

Chronic metabolic acidosis enhances NHE 3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE 3 mRNA

... Chronic metabolic acidosis (CMA) is associated with an adaptive increase in the bicarbonate absorptive capacity of the rat medullary thick ascending limb ...• acidosis • ...

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Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis

Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis

... of metabolic acidosis can be catastrophic and a considerable body of literature highlights the poor out- look in patients where lactic acid is the principal component of the acidaemia ...group, ...

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Lactate versus non lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients

Lactate versus non lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients

... of acidosis subtypes between patients with and without renal dysfunction (defined as a serum creatinine level of more than 2 mg/dl), we found less hyperchloremic and more lactic acidosis in the patients ...

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The Internal Distribution of Hydrogen Ions With Varying Degrees of Metabolic Acidosis

The Internal Distribution of Hydrogen Ions With Varying Degrees of Metabolic Acidosis

... Initial extracellular fluid volume was taken to be 20 per cent of body weight and subsequent alterations estimated from changes in the "chloride space." The buffer contribution of extrac[r] ...

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METABOLIC ACIDOSIS IN CHILDREN WITH SEVERE CYANOTIC CONGENITAL HEART DISEASE

METABOLIC ACIDOSIS IN CHILDREN WITH SEVERE CYANOTIC CONGENITAL HEART DISEASE

... maintain a normal acid-base balance in the cyanotic children with markedly diminished pulmonary blood flow, and the acid load was imposed, therefore, on the latter two systems. The low s[r] ...

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A Diagnostic Approach to Metabolic Acidosis in Children

A Diagnostic Approach to Metabolic Acidosis in Children

... If the Cl is normal and there is an increased gap, the acidosis (or acidemia) probably results from excess acid production or advanced renal disease. In the latter situation, when renal [r] ...

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The influence of salt intake on the metabolic acidosis of chronic renal failure

The influence of salt intake on the metabolic acidosis of chronic renal failure

... DISCUSSION The present study demonstrates, first, that constant dietary salt administered throughout the progression of experimental chronic renal failure is associated with a marked bic[r] ...

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The response of the kidney of the freshwater rainbow trout to true metabolic acidosis

The response of the kidney of the freshwater rainbow trout to true metabolic acidosis

... Renal excretion of lactate anion and total acid increased by approximately equal amounts during the period of high blood lactate levels, but total renal loss over 72 h accounted for only[r] ...

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Glutamine Transport in Rat Kidney Mitochondria in Metabolic Acidosis

Glutamine Transport in Rat Kidney Mitochondria in Metabolic Acidosis

... The mitochondria rapid metabolism of glutamine by mitochondria from from the 3-h acidotic rats had a lesser, but still highly kidney and they show that ["C]glutamate formed from signific[r] ...

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Pseudohypoaldosteronism in a neonate presenting as life-threatening arrhythmia

Pseudohypoaldosteronism in a neonate presenting as life-threatening arrhythmia

... hyponatremia, metabolic acidosis, and life-threatening hyperkalemia with normal glomerular filtration rate (GFR) (calculated as Schwartz) formula: height ...

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