Metabolomic Approach
Biomarker discovery in neurological diseases: a metabolomic approach
... This approach is considered to have the potential to revolutionize medical practice in preventing, predicting, and personalizing brain health ...Through metabolomic approach, plasma and serum, could ...
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A metabolomic approach to understand the solid-state fermentation of okara using Bacillus subtilis WX-17 for enhanced nutritional profile
... untargeted metabolomic approach using gas chromatography-mass spectrophotometry (GC–MS) was carried out to analyse the value-added products pro- duced in okara fermented with ...
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A metabolomic approach to target compounds from the asteraceae family for dual COX and LOX inhibition
... this metabolomic approach was employed to find biomarkers for a specific biological activity which in parallel also give us a chemotaxonomic insight of the investigated species from ...
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A dried blood spot mass spectrometry metabolomic approach for rapid breast cancer detection
... Except mentioned specifically, all the tests were conducted at room temperature. A 3 mm (diameter) disc was punched from each DBS paper. The discs were placed into the Millipore MultiScreen HV 96-well plate (Millipore, ...
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A multiplatform metabolomic approach to characterize fecal signatures of negative postnatal events in chicks: a pilot study
... In contrast, liquid extraction of freeze-dried feces followed by LC-HRMS or GC-MS was reproducible, and the OPLS- DA model fitted on those data highlights persisting differ- ences in ada[r] ...
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A Metabolomic Approach (1H HRMAS NMR Spectroscopy) Supported by Histology to Study Early Post-transplantation Responses in Islet-transplanted Livers
... an approach that produces highly resolved spectra used to identify and quantify multiple metabolites directly on small pieces of untreated intact tissues (< 20 mg) ...of metabolomic applications mainly ...
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Metabolomic approach to profile functional and metabolic changes in heart failure
... the metabolomic fingerprint of the disease and its relationship with the levels of N-ter- minal of the prohormone brain natriuretic peptide and New York Heart Association (NYHA) classes in patients with chronic ...
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Serum metabolites in non-alcoholic fatty-liver disease development or reversion; a targeted metabolomic approach within the PREDIMED trial
... Recently, several studies focused on NAFLD associ- ation with metabolism of complex lipid classes. Follow- ing this approach, Puri et al. [8] reported perturbations in hepatic lipid classes, during progression ...
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A metabolomic approach to identifying platinum resistance in ovarian cancer
... The significantly altered metabolites categorized under cysteine and methionine metabolism included: 5- methylthioadenosine, cystathione, cysteine, cysteine sul- funic acid, cysteine and[r] ...
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Metabolomics Analysis of the Responses to Partial Hepatectomy in Hepatocellular Carcinoma Patients
... The schematic flowchart of the metabolomic approach performed in this study was illustrated in the Figure 1. Briefly, the metabolites from sera were extracted and applied to HPLC coupled with electrospray ...
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Arbuscular Mycorrhizal Fungi and Plant Chemical Defence: Effects of Colonisation on Aboveground and Belowground Metabolomes
... non-targeted metabolomic approaches have been used to in- vestigate the effects of AMF on a wide range of metabolites (the metabolome) in foliar tissues (Fester et ...a metabolomic approach to show ...
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Assessment of dietary exposure related to dietary GI and fibre intake in a nutritional metabolomic study of human urine
... a metabolomic approach for measuring influence of different dietary patterns related to ad libitum dietary intake on the urine metabolome in a 6-month randomised, controlled dietary intervention study with ...
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Microbial Succession and Flavor Production in the Fermented Dairy Beverage Kefir
... In summary, in this study, it has been demonstrated that a combined metagenomic and metabolomic approach can potentially be used to identify the microbes from a particular environment th[r] ...
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The HPTLC approach to metabolomic determination of neem products composition
... Metabolomic approach can be epitomized as the study of small molecules as many as possible. In order to face and solve the chemical complexity of neem, we selected HPTLC as the adequate analytic tool. ...
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Plasma sphingolipids in HIV-associated chronic obstructive pulmonary disease
... untargeted metabolomic approach, we identi fi ed 172 unique plasma analytes that associated with HIV-COPD com- pared with participants with HIV without COPD after controlling for multiple confounders such as ...
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Metabolomic and BH3 profiling of esophageal cancers: novel assessment methods for precision therapy
... whether metabolomic signatures in tumor, blood, or urine or BH3 profiling in tumor of EAC and ESCC patients correlate with major responses (Mandard score of 1 and 2) versus minimal response (Mandard score ...
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Plasma metabolomic profiling of proliferative diabetic retinopathy
... Diabetic retinopathy, acknowledged as a chronic meta- bolic disease, is the mainly cause of blindness among working-age adults throughout the world [1]. Without treatment, it easily leads to vision loss and affect the ...
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High quality metabolomic data for Chlamydomonas reinhardtii
... were combined. Extracts were dried and prepared for metabolite profiling as given in the methods section. A typical GC-TOF chromatogram consisted of about 750 peaks that were detectable at s/n 10 using the ChromaTOF vs. ...
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1 Metabolomic study of polyamines in rat urine
... in multivariate analysis, but it maintained a similar level in GHB single and multiple administration 205. groups[r] ...
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The application of metabolomic profiling to the effects of physical activity
... observed that fatty acid release into plasma decreased with increasing exercise intensity [83] and fatty acid levels in plasma increased greatly during the minutes following a high-inten[r] ...
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