Mevalonic acid
Studies of the In Vivo Metabolism of Mevalonic Acid in the Normal Rat
... Studies were performed to examine synthesis, tissue localization, and metabolism of mevalonic acid in normal rats. Circulating mevalonate was found to have a rapid turnover phase of 5 min and a slower phase ...
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Quantification of urinary mevalonic acid as a biomarker of HMG-CoA reductase activity by a novel translational LC-MS/MS method
... Background: Mevalonic acid (MVA), as a product of 3-hydroxy-3-methylglutaryl coenzyme A reductase, represents a potential multipurpose biomarker in health and ...
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The isomiR 140 3p regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer
... a, b The mevalonate pathway, where statin treatment triggers a restorative feedback loop leading to upregulation of HMGCR mRNA levels a and aspirin and metformin put a brake in this rest[r] ...
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Extraction of short chain organic acids using imidazolium based ionic liquids from aqueous media
... the mevalonic acid was more easily back extracted into distilled water and the extraction efficiency could be up to ...citric acid and lactic acid had a lower partition coefficients of back ...
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Mevalonate kinase deficiencies: from mevalonic aciduria to hyperimmunoglobulinemia D syndrome
... in mevalonic aciduria: development of a stable isotope dilution GCMS assay for mevalonic acid and its appli- cation to physiological fluids, tissue samples, prenatal diag- nosis and carrier ...
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Systemic control of soybean nodule autoregulation
... 7 .2 DESIGN 81 4.7.3 RESULTS 82 Figure 4.3: Incorporation profile of 14 C - mevalonic acid into Bragg and nts382 shoot tissues YBEAN NTR L F HAPTER 5: H T ENETI NODULATION IN SPLIT ROOT [r] ...
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Studies on Gibberellic acid production by Bacillus licheniformis DS3 isolated from Banana field soils
... gibberellic acid production and can be further explored for its utilization for plant growth promoting ...different mevalonic acid concentrations and also different carbon and nitrogen sources ...
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Mevalonate Kinase Deficiency: Enlarging the Clinical and Biochemical Spectrum
... Patient 3 is a 6-year-old boy and the second child of healthy, unrelated parents. He was born after an uneventful pregnancy at 40 weeks of gestation. Birth weight was 3400 g, length was 49 cm, head circumference was 35 ...
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EFFECTS OF TRIPARANOL (MER 29) ON CHOLESTEROL BIOSYNTHESIS AND ON BLOOD STEROL LEVELS IN MAN
... Comparison of specific radioactivities of serumfree desmosterol and serum free cholesterol 4 hours after intravenous injection of 2-C'4-mevalonic acid in patients under treatment with ME[r] ...
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The Use of Anisaldehyde Sulfuric Acid as an Alternative Spray Reagent in TLC Analysis Reveals Three Classes of Compounds in the Genus Usnea Adans. (Parmeliaceae, lichenized Ascomycota)
... medulla. In addition, compounds derived from the mevalonic acid pathway (e.g. terpenoids and steroids) are sometimes detected in the medulla [5]. However, their identity and value as diagnostic characters ...
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Metabolic alteration of Catharanthus roseus cell suspension cultures overexpressing geraniol synthase in the plastids or cytosol
... of mevalonic acid as precursor did not directly stimulate TIA production in the ΔplCrGES transformed cell lines; presumably the level of free cytosolic GPP in these cells is too low to support detectable ...
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Formation of carboxylic acids during degradation of monosaccharides
... responding acid. Furthermore, pyruvic acid may be formed by oxidation of methylglyoxal and can consecutively decarboxylate yielding ...pyruvic acid in our model systems supports this reaction ...
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A study of the fatty acid profile in the muscle of Monopterus chuchia
... fatty acid composition of this fish (Monopterus chuchia) which is gradually becoming a vulnerable one due to indiscriminate fishing, suggests that the fish has considerable nutritional capacity from the finding ...
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ANTIBACTERIAL ACTIVITY AND GCMS ANALYSIS OF THE EXTRACT OF LEAVES OF RHIZOPHORA APICULATA (A MANGROVE PLANT)
... Ursolic acid was reported to be cytotoxic against A- 549, L-1210 and KB tumour cells (Yamagishi et ...oic acid was found to exhibit anti-ulcer properties (Fourie et ...palmitic acid as major ...
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In Vitro Metabolite Colonic Production from Otili (Sphenostylis stenocarpa) as Influenced by Selected Gastrointestinal Microbes
... fatty acid examined, either saturated or unsaturated [32] [33] ...erucic acid appears to have toxic effects on the heart at high enough doses [35] ...erucic acid and other ingredients [39], there are ...
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Gas Chromatography-Mass Spectrometry Analysis of the Anti-MRSA Fractions of Chromolaena odorata (L.) R.M. King & H. Rob. leaves
... donebecause it was not distinctly isolated) showed anti- MRSA activities at 2.0 mg/ml. The least mean zone of inhibition against MRSA isolates was 8.0 mm for F5 and the highest was 22.5 mm for F2 and F3. There was ...
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... palimitic acid, palmitoleic acid, stearic acid, oleic acid, linoleic acid, alpha linoleic acid, arachidic acid, eicosanoic acid, behenic acid, and erucic ...
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Natural Antioxidant Changes in Fresh and Dried celery (Apium graveolens)
... chlorogenic acid, syringic acid, caffeine , p- coumaric acid, ferulic acid, salycilic acid, cinnamic acid, chrysin, pyrogallol , ellagic acid , catechin and caffeic ...
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Journal of Applied Pharmaceutical Science
... quinic acid, the peak 5 has shown an m/z of 353 which is the indication of chlorogenic acid, the peak 8 has shown an m/z of ...tr-caffeic acid, the peak 10 has shown an m/z of ...p-coumaric ...
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Mechanistic and stereochemical studies on methylaspartase and glutamate mutase
... The fact that the ^^(V/K) values are the same for the protio and deuterio substrates supports the notion that elimination occurs via a concerted mechanism. However the lack of a substantial observed ^^(V/K) effect , in ...
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