MexAB-OprM
EFFECT OF GAMMA AND BETA RADIATION ON MULTI –DRUG RESISTANT(MDR) PSEUDOMONAS AERUGINOSA RESISTANCE COLISTIN ISOLATED FROM SKIN, BURNS, WOUND INFECTIONS AND INHIBITION OF MEXXY, MEXAB OPRM EFFLUX PUMPS
... and MexAB-OprM efflux pumps by studied mexB and mexX gene, The results showed that gene expression were high to MexXY and MexAB- OprM efflux pumps of ...and MexAB- OprM efflux ...
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Nosocomial Outbreak of a Non Cefepime Susceptible Ceftazidime Susceptible Pseudomonas aeruginosa Strain Overexpressing MexXY OprM and Producing an Integron Borne PSE 1 ß Lactamase
... Quantification of gene expression by RT-PCR. To quantify the expression of the chromosomal ß-lactamase AmpC and several efflux pumps (MexAB-OprM, MexCD-OprJ, MexEF-OprN, and MexXY-OprM), the relative ...
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Expression of the MexXY-OprM efflux system in <em>Pseudomonas aeruginosa</em> with discordant cefepime/ceftazidime susceptibility profiles
... The poor correlation between the cefepime/ceftazidime MIC ratio and the overexpression of mexY may be explained by the presence of other resistance mechanisms (ie, β -lactamases, outer-membrane proteins and/or other ...
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Emergence of colistin resistant Pseudomonas aeruginosa at Tabriz hospitals, Iran
... of MexAB-OprM and MexXY-OprM efflux pumps, while colistin is not a specific substrate of these efflux systems ...the mexAB-oprM gene is expressed by the active subpopulation of ...
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Evaluation of effluxpumps gene expression in resistant Pseudomonas aeruginosa isolates in an Iranian referral hospital
... Background and Objectives: Pseudomonas aeruginosa (PA) is one of the most important causes of nosocomial infections and has an intrinsic resistance to many antibiotics. Among all the resistance-nodulation-division (RND) ...
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Detection of DNA Gyrase Mutation and Multidrug Efflux Pumps Hyperactivity in Ciprofloxacin Resistant Clinical Isolates of Pseudomonas aeruginosa
... Genotypic analysis of fluoroquinolone resistance has been previously reported in clinical isolates of P. aeruginosa [21, 28-30]. In this study, we re- ported the first genotypic analysis of major multi- drug efflux pumps ...
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Enhancement of antibiotic efficacy against multi drug resistant Pseudomonas aeruginosa infections via combination with curcumin and 1 (1 Naphthylmethyl) Piperazine
... overexpresses MexAB-OprM (PAM1032) to PIP, MEM and LVX, with or without the presence of CUR or NMP, is shown in Table ...of MexAB-OprM) occurred with these drugs ...of MexAB-OprM ...
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<p>Molecular Epidemiology and Mechanisms of High-Level Resistance to Meropenem and Imipenem in <em>Pseudomonas aeruginosa</em></p>
... MexAB-OprM over-expression was observed in 21.8% of the isolates, concurring with Xavier and co-workers. 44 In contrast, Dantas et al 7 and Chalhoub et al 32 reported a much higher frequency of ...
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Investigation of aminoglycoside resistance inducing conditions and a putative AmrAB-OprM efflux system in Burkholderia vietnamiensis
... Conclusions: These data identify oxidative stress as an inducer of aminoglycoside resistance in B. vietnamiensis and further suggest that active efflux via a RND efflux system impairs aminoglycoside accumulation in ...
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