microRNA-203
Original Article Quantification of the differential expression levels of microRNA-203 in different degrees of diabetic foot
... Skin-enriched microRNA-203 (miR-203) was readily detected in skin tissue samples, and, in contrast to normal skin tissue, samples from patient with diabetic foot ulcers significantly have a higher ...
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Human Papillomaviruses Modulate Expression of MicroRNA 203 upon Epithelial Differentiation to Control Levels of p63 Proteins
... is microRNA 203 (miR-203), which is expressed primarily in suprabasal epithelial ...this microRNA to allow productive replication in differentiating ...
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Original Article MicroRNA-203 inhibits proliferation and induces apoptosis of neuroblastoma SH-SY5Y cell via upregulation of TGF-β1/BIM signal
... treatment, while others can progress and lead to the death of the patient in spite of intensive multi-modal chemotherapy [7]. Recently, it has been shown that overexpression of miR-203 inhibited the proliferation, ...
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Direct cell fate conversion of human somatic stem cells into cone and rod photoreceptor-like cells by inhibition of microRNA-203
... novel microRNA-mediated strategy of retina differentiation from somatic stem cells, which are potential allogeneic cell ...Furthermore, microRNA-203 (miR-203) is abundantly expressed in human ...
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Association between underexpression of microrna-203 and clinicopathological significance in hepatocellular carcinoma tissues
... that microRNA-203 (miR-203) exhibited significantly down-regulated expres- sion in prostate cancer [18], hematopoietic malignancy [19], colon cancer ...
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Original Article Effects of microRNA-203 on Farage cell apoptosis in diffuse large B cell lymphoma
... Cultured Human DLBCL cell line Farage cells were divided into 5 groups: non-treated group, mimic NC control, miR-203 mimic group, si-NC group, si-Survivin group, and miR-203 mimic + si-Survivin group. ...
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MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells
... BIRC5 is expressed during embryonic and fetal devel- opment but is undetectable in terminally differentiated normal adult tissue. However, it is re-expressed in human cancer cells at a frequency of 34-100% [18,19]. BIRC5 ...
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RETRACTED ARTICLE: MicroRNA-203 suppresses gastric cancer growth by targeting PIBF1/Akt signaling
... High recurrence rate and rapid tumor growth remain the major cause of increase GC survival rate. Therefore, it is indispensable to gain a better understanding of the mechanisms of GC proliferation. MiRNAs related to ...
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Targeting deubiquitinating enzyme USP26 by microRNA-203 regulates Snail1’s pro-metastatic functions in esophageal cancer
... We next wanted to determine if the in vitro findings of miR-203-mediated regulation of USP26 and pro-met- astatic functions will hold in in vivo mice models of metastasis. Mice injected with parental Kyse150 cells ...
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Epstein-Barr Virus Downregulates MicroRNA 203 through the Oncoprotein Latent Membrane Protein 1: a Contribution to Increased Tumor Incidence in Epithelial Cells
... miRNA 203 (miR-203) was downregulated. miR-203 is expressed specifically in epithelial ...miR- 203 was further verified and functionally analyzed. miR-203 was downregulated ...
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Androgen receptor regulates SRC expression through microRNA-203
... To compare miR-203 expression levels with PCa progression and survival and with AR and SRC expression levels, we used miR and mRNA expression data from the Taylor PCa dataset [30] and the Cancer Genome Atlas ...
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MicroRNA 203 Expression in Keratinocytes Is Dependent on Regulation of p53 Levels by E6
... mechanisms underlying miR-203 control of p63 levels were likely to be complex, may include other miRNAs, and may be subject to other factors. One such factor may be p53, since there is evidence to suggest that p63 ...
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Rapid and widespread suppression of self renewal by microRNA 203 during epidermal differentiation
... miR-203 is thought to have an important role during epidermal differentiation (Yi et al., 2008). However, the precise dynamics of the upregulation of miR-203 remain unclear. We set out to determine the ...
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Original Article Prognostic significance of microRNA-203 in cholangiocarcinoma
... Abstract: MircroRNA functions as a tumor suppressor or a promoter in cholangiocarcinoma (CCA). Researchers have found that miR-203 functioned as tumor suppressor in many types of cancer. However, the role of ...
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Overexpression of KLF4 promotes cell senescence through microRNA-203-survivin-p21 pathway
... T-REx-293 KLF4 cells with or without 2 μg/ml doxycycline treatment for three days were harvested and washed in cold sterile phosphate buffered saline (PBS), and then miRNA was isolated using a mirVana RNA isolation kit ...
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Original Article Diagnostic and prognostic significance of serum miR-203 in patients with acute myeloid leukemia
... cer types. In breast cancer (BC), significantly lower miR-203 expression was detected in metastatic BC cells and cell lines, and ectopic miR-203 expression could inhibit cell invasion, migration, and lung ...
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Identifying MicroRNA Precursors Using Linear Dimensionality Reduction With Explicit Feature Mapping
... The authors obtained a total number of 2,241 pre-microRNAs from miRBase 8.2. They used 200 human pre-microRNAs and 400 randomly selected pseudo hairpins for training and finding parameters of miPred and called it TR-H. ...
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Differences in microRNA expression between melanoma and healthy adjacent skin
... KEGG pathway analysis based on microRNA signature was performed with DIANA-mirPath v.3.0. MicroRNA targets were predicted with the use DIANA-microT-CDS computational tool. The threshold (P ≤ 0.05) and false ...
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Original Article Hypermethylation and low expression of miR-203 in patients with esophageal cancer in Chinese population
... Genomic DNA of esophageal cancer and control tissueswas extracted using thetissue DNA kit (TIANGEN, China), and then dissolved in TE bufferand stored at -20°C. Promoter methylation of miR-203 gene was deter- mined ...
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Original Article Down-regulation of microRNA-126 and microRNA-133b acts as novel predictor biomarkers in progression and metastasis of non small cell lung cancer
... Assays and reagents from the TaqMan MicroRNA Reverse Transcription kit (Applied Biosystems). Real-time PCR was carried out to detect the expression level of microRNAs using an Invitrogen kit by system of ...
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