Microscopic Polyangiitis
Antineutrophil cytoplasmic antibody-positive conversion and microscopic polyangiitis development in patients with idiopathic pulmonary fibrosis
... ANCA-associated vasculitis. 1 2 ANCAs directed against proteinase 3 (PR3) are detected mainly in patients with granulomatosis with polyangii- tis, whereas ANCAs directed against myeloper- oxidase (MPO) are found ...
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Case Report Spontaneous rupture of kidneys triggered by microscopic polyangiitis
... Rationale: Microscopic polyangiitis (MPA) is defined by the 2012 revised Chapel Hill Consensus Confer- ence Nomenclature of Vasculitides as necrotizing vasculitis, with few or no immune deposits, ...
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Different responses to treatment across classified diseases and severities in Japanese patients with microscopic polyangiitis and granulomatosis with polyangiitis: a nationwide prospective inception cohort study
... with polyangiitis; EMEA: European Medicines Agency; ESRD: end-stage renal disease; EULAR: European League Against Rheumatism; EUVAS: European Vasculitis Study Group; GC: Glucocorticoids; GFR: Glomerular filtration ...
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A 10-Year Old Boy with Pulmonary-Renal Syndrome and Diagnosis of Microscopic Polyangiitis
... At the Chapel Hill consensus conference, MPA was defined as necrotizing vasculitis of small vessels, with few or no immune deposits, but involvement of medium-sized arteries may also be observed (5). Kandeel et al. ...
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Microscopic polyangiitis associated with thymic tumor: a case report and review of the literature
... Light microscopic findings of a renal biopsy sample showed cellular crescents in 50% of 14 obtained glomeruli, and a fibrocellular crescent was revealed in one of those ...diagnosed microscopic ...
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Microscopic polyangiitis secondary to Mycobacterium abscessus in a patient with bronchiectasis: a case report
... Case presentation: A 70 year old female with bronchiectasis underwent a clinical decline associated with the growth of M.abscessus and was diagnosed with NTM-PD. Before treatment could be initiated she developed small ...
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Increased serum levels of macrophage migration inhibitory factor (MIF) in patients with microscopic polyangiitis
... vessels. Microscopic polyangiitis (MPA) was considered as small vessel vasculitis (SVV), polyarteritis nodosa as medium-sized vessel vasculitis (MVV), and giant cell arteritis and Takayasu arteritis as ...
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Microscopic polyangiitis complicated with ileal involvement detected by double-balloon endoscopy: a case report
... Microscopic polyangiitis (MPA) is pauci-immune, necro- tizing vasculitis of small vessels without necrotizing granu- ...with polyangiitis and allergic granulomatous ...
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Prediction of response to remission induction therapy by gene expression profiling of peripheral blood in Japanese patients with microscopic polyangiitis
... MPA: Microscopic polyangiitis; MS4A4A: Membrane-spanning 4-domains, subfamily A, member 4; OASL: 2 ′ -5 ′ -Oligoadenylate synthetase-like; PCR: Polymerase chain reaction PLSCR1, Phospholipid scramblase 1; ...
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Place in therapy of rituximab in the treatment of granulomatosis with polyangiitis and microscopic polyangiitis
... with polyangiitis and microscopic polyangiitis are small vessel vasculitides characterized by circulating antineutrophil circulating ...with polyangiitis and microscopic ...
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Childhood-onset granulomatosis with polyangiitis and microscopic polyangiitis: systematic review and meta-analysis
... with polyangiitis (Churg-Strauss); EMA: European medicines agency; ENT: Ear, nose and throat; ESRD: End-stage renal disease; EULAR: European league against rheumatism; FDA: Food and drug administration; GPA: ...
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Clinical characteristics and outcomes in microscopic polyangiitis patients with renal involvement: a study of 124 Chinese patients
... A pre- vious study showed that a peak serum creatinine level greater than 4.5 mg/dl (397.8 μ mol/L) at the time of diagnosis is a predictive factor for ESRF or death in AAV patients [ 39[r] ...
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Fibrosis-4 index at diagnosis is associated with all-cause mortality in patients with microscopic polyangiitis and granulomatosis with polyangiitis
... The critical cut-off of FIB-4 for predicting significant liver fibrosis (S2 or greater) is currently set as 1.45 [10]. Recently, it has been reported that the baseline FIB-4 is significa[r] ...
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Anti-neutrophil cytoplasmic antibody-associated glomerulonephritis with detection of myeloperoxidase and phospholipase A2 receptor in membranous nephropathy-lesions: report of two patients with microscopic polyangiitis
... After the referral, his proteinuria progressed to neph- rotic syndrome. Physical examination showed bilateral fine crackles and pitting edema in the feet. His urinary protein excretion was 15.9 g/g urinary creatinine. ...
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A retrospective study of microscopic polyangiitis patients presenting with pulmonary fibrosis in China
... Within 2 to 6 weeks of their initial diagnosis, six of the patients diagnosed with MPA had pulmonary fibrosis. Pulmonary fibrosis was seen to predate the diagnosis of MPA for the other 13 cases, with a mean delay of 9.5 ...
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Sigmoid colon perforation in the patient with granulomatosis with polyangiitis
... There is published literature on gastrointestinal in- volvement in systemic necrotizing vasculitis. Earlier re- ports showed that GPA patients presented with diarrhea, hematochezia, and gastrointestinal ulcers [5–7]. ...
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ANCA-Associated Vasculitis: Advancement in Pathogenesis, Clinical Features and Management
... Granulomatous Polyangiitis (GPA), Microscopic Polyangiitis (MPA), and Eosinophilic Granulomatosis with Polyangiitis (EGPA) are the main AAVs types which usually affect small-vessels and ...
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Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia
... with polyangiitis (GPA) is an autoimmune inflammatory disorder affecting the small and medium sized blood vessels of the body ...with Polyangiitis (EGPA), polyarteritis nodosa, and microscopic ...
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BCL3, CD14, CXCL11, CXCL9, FADD, IL10, IRAK3, IRF7, MUC1, TLR1, TLR4, TLR6, (TOLLIP) were up-regulated and 10 genes ( ATF3, CHUK, CIITA, CXCL10, IFNA7, JUN, RIPK2, SARM1, SOCS1, TLR10
... Abstract: Recent, emerging evidence indicates that inappropriate regulation of toll-like receptor (TLR) signaling pathway plays a fundamental role in the development of autoimmune diseases including microscopic ...
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Granulomatosis with Angitis of Lung treated with Steroids and Rituximab– Case Report and Review of Literature
... and Microscopic Polyangiitis)was a randomized, placebo-controlled, multicenter noninferiority trial that compared induction therapy with rituximab (375 mg/m 2 per week for four weeks) or with oral ...
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