mitochondrial permeability transition
Mitochondrial Respiration Is Associated with Alloxan Induced Mitochondrial Permeability Transition
... increased mitochondrial inner membrane permeability which is known as mitochondrial permeability transition (MPT) is triggered by add- ing succinate in the presence of the diabetogenic ...
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Flurbiprofen, a Cyclooxygenase Inhibitor, Protects Mice from Hepatic Ischemia/Reperfusion Injury by Inhibiting GSK-3β Signaling and Mitochondrial Permeability Transition
... inhibited mitochondrial permeability transition (MPT) pore opening, and thus prevented mitochondrial-related cell death and ...ameliorates mitochondrial and hepatocellular damage ...
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Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition
... chondrial permeability transition pore (MPTP) is a protein channel that spans the inner and outer mem- branes of mitochondria ...of mitochondrial membrane potential, which is called ...
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Modulation of Mitochondrial Permeability Transition Pore Affects Multidrug Resistance in Human Hepatocellular Carcinoma Cells
... MDR. Mitochondrial permeability transition (mPT) is implicated as an important event in the control of cell death or survival and mPT represents a target for the development of cytotoxic ...of ...
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Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease
... Background: Mitochondrial impairment has been implicated in the pathogenesis of Huntington ’ s disease ...impairs mitochondrial function and thus contributes to HD has not been fully ...compromising ...
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Glycogen synthase kinase 3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore
... the mitochondrial permeability transition (MPT) in cardiomyocytes and that cell survival is steeply negatively correlated with the fraction of depolarized ...triggered mitochondrial swelling ...
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The effect of quercetin on oxidative stress markers and mitochondrial permeability transition in the heart of rats with type 2 diabetes
... of mitochondrial permeability transi- tion in cardiomyocytes are linked to tissue damage and the development of diabetic cardiovascular complica- ...and mitochondrial permeability ...
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Regulation of mitochondrial permeability transition pore by PINK1
... the mitochondrial respiration defects caused by loss of ...evaluate mitochondrial functions in intact ...[18], mitochondrial respiration is impaired in PINK1 −/− MEFs, indicating that these cells ...
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Circular RNA CircEZH2 Suppresses Transmissible Gastroenteritis Coronavirus-induced Opening of Mitochondrial Permeability Transition Pore via Targeting MiR-22 in IPEC-J2
... provokes mitochondrial damage of porcine intestinal epthelial cell (IPEC), which is responsible for inflammation and cell ...for mitochondrial damage. Mitochondrial permeability ...
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Hepatitis B Virus X Protein Modulates Apoptosis in Primary Rat Hepatocytes by Regulating both NF-κB and the Mitochondrial Permeability Transition Pore
... the mitochondrial permeability transition pore inhibited HBx activation of ...the mitochondrial permeability transition ...
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Cadmium induced apoptosis in oyster hemocytes involves disturbance of cellular energy balance but no mitochondrial permeability transition
... that low ATP levels per se do not shift the form of cell death towards necrosis in these cells. A characteristic feature of the cellular physiology of intertidal mollusks, including oysters, is their capability for ...
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Imaging the mitochondrial permeability transition in single cells: Free radicals and calcium as determinants of cell fate
... activation. Mitochondrial involvement in apoptotic cell death was confirmed when Liu et al observed that caspase activation in a cell-free system required ATP and cytochrome c (Liu e ta ...the mitochondrial ...
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Hepatitis C Virus Triggers Mitochondrial Permeability Transition with Production of Reactive Oxygen Species, Leading to DNA Damage and STAT3 Activation
... the mitochondrial respiratory chain enzymes and triggers blockade of the electron transfer chain and disruption of the mitochon- drial transmembrane potential (14, ...
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Effect of Fish and Flaxseed Oil Supplementation on Isoprenaline-Induced Myocardial Infarction in Rats: Inhibition of Mitochondrial Permeability Transition Pore Opening
... Materials and Methods: The study was conducted on 40 male Wistar rats which were included in control, ISO, FO + ISO, and FLO + ISO groups (each containing 10 rats). In ISO rats, acute myocardial ischemia was induced by ...
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The influence of ATP-dependent K(+)-channel diazoxide opener on the opening of mitochondrial permeability transition pore in rat liver mitochondria
... Возврат Са 2+ в матрикс после перевода поры в закрытое со- стояние с помощью циклоспорина А также по- казывает, что при открывании поры происхо- дит активация циклического транспорта С[r] ...
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<p>Lycopene protects against myocardial ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening</p>
... MPTP opening usually leads to the release of cytochrome c, subsequently leading to the activation of caspases. Western blot analysis performed by the present study revealed that in the LP treatment group, the expression ...
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Protective effects of potassium transport in mitochondria from rat myometrium under activation of mitochondrial permeability transition pore
... inner membrane of mitochondria is thus impermea ble to ions, and their matrix homeostasis is regulated via functioning of ion transporting systems of chan nels and exchangers [1, 2]. The mitochondrial ion ...
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ACTIVITY OF APIGENIN AND QUERCETIN ON RAT HEPATIC MITOCHONDRIAL PERMEABILITY TRANSITION PORE
... The results obtained from this study showed that calcium ions induced the opening of MMPT pore significantly (P<0.05) in rat liver mitochondrial, while spermine inhibited calcium-induced opening of MMPT pore. ...
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Anoxia mediated calcium release through the mitochondrial permeability transition pore silences NMDA receptor currents in turtle neurons
... the mitochondrial phosphate carrier or ATP synthase form protein complexes that produce mitochondrial permeation (Varanyuwatana and Halestrap, 2012; Giorgio et ...a permeability-favouring ...
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Nitric Oxide and Peroxynitrite: Effects on Cardiovascular Function
... of mitochondrial permeability transition pore, mitochondrial depolarization, secondary O 2 ·- production, release of apoptotic mediators ...
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