mitogen-activated protein kinase-activated protein kinase
Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5)
... on mitogen-activated protein kinase-activated protein kinase 5 ...MK5 protein is a highly conserved protein kinase within vertebrates sharing 87 to ...
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Modulation of Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 by Hepatitis C Virus Core Protein
... the protein array data, we per- formed an in vitro binding assay using His-tagged core protein purified from ...core protein interacted with endogenous MAPKAPK3 in ...bound protein was ...
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Regulation of the mitogen activated protein kinase p44 ERK activity during anoxia/recovery in rainbow trout hypodermal fibroblasts
... inactive kinase to the nuclear compartment (Mizukami and Yoshida, ...was activated in response to reperfusion, suggesting an interface capable of ERK activation in the nuclear ...3- kinase) and the ...
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MAP2K6 is associated with radiation resistance and adverse prognosis for locally advanced nasopharyngeal carcinoma patients
... are protein kinases, and there are > 500 kinases in the mammalian ...genome. Protein kinases, such as receptor tyrosine kinases, cyclin- dependent kinases, and MAP kinases (MAPKs) accounts for the ...
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Original Article Association detection between genetic variants in the microRNA binding sites of toll-like receptors signaling pathway genes and bladder cancer susceptibility
... TLRs signaling pathway genes polymorphisms and bladder cancer risk mitogen-activated protein kinase 1 protein kinase C, beta 1 protein kinase C, alpha protein kinase, cAMP-dependent, reg[r] ...
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Mitogen-Activated Protein Kinase Pathways and Fungal Pathogenesis
... Although C. albicans is a diploid fungus traditionally classi- fied as asexual, mating between genetically modified strains and a parasexual cycle have been observed. CEK2 (25) and several components of the CEK1 pathway, ...
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Flavonoids in modulation of cell survival signalling pathways
... Abstract Flavonoids, a family of polyphenols, generally found in various fruits and vegetables, as well as in many plant beverages such as tea, pomegranate juice, raspberry, blueberries, and red wine. Recently, studies ...
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Kinase Activity Profiling of Gram-Negative Pneumonia
... approach. Kinase activity arrays enable the analysis of 1,024 con- sensus sequences of protein kinase ...a kinase activity array on whole lung lysates, cellular kinase activities were ...
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Regulation of Sox9 activity by crosstalk with nuclear factor κB and retinoic acid receptors
... active mitogen-activated protein kinase kinase kinase (caMEKK)1 (Clontech, Mountain View, CA, USA), a phosphorylation site- deficient IκB (IκB-2N; pSVK3-IκB-2NΔ4) [30], or ...
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Enhanced expression of microtubule-associated protein 7 functioned as a contributor to cervical cancer cell migration and is predictive of adverse prognosis
... of mitogen‑activated protein kinase kinase (MEK) and extracellular signal‑regulated kinase (ERK) in Caski and HeLa cells, and overexpression of MAP7 increased their ...
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Stem cells and the impact of ROS signaling
... modify protein function, the opposite is also true: a growing network of proteins have been shown to modulate ROS levels ...thioredoxin-interacting protein (TXNIP) may be implicated in hematopoietic stem ...
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A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases
... interacting protein kinase (HIPK) 2 and 3, I-kappa B Kinase (IKK), mitogen-activated pro- tein kinase 1 (MAPK2/ERK2), ribosomal protein S6 kinase, 90 kDa, ...
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Supplementing L-isoleucine increases medium protein and alters the expression of genes and proteins involved in milk protein synthesis and energy metabolism in bovine mammary cells
... milk protein synthesis, using an immortalized bovine mammary epithelial (MAC-T) cell ...for protein synthesis for each amino acid was determined by measuring the cell, medium and total protein at 0, ...
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Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein.
... The PKCl gene product, protein kinase C, regulates a mitogen-activated protein kinase (MAPK) cascade, which is implicated in cell wall metabolism.. Previously, we i[r] ...
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MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts
... G protein- coupled signaling pathways including mitogen-activated protein kinase (MAPK), which subsequently induce sev- eral cellular responses including gene expression and pulmonary ...
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Identification and Characterization of MAPK Phosphorylation Sites in Runx2
... The Mitogen-activated protein kinase (MAPK) pathway plays an important role in osteoblast growth and ...be activated by MAPK in COS-7 cells by ...dramatically activated by ...
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From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis
... kinase 2; MKK3: Mitogen-activated protein kinase kinase kinase 3; MKK4: Mitogen- activated protein kinase kinase kinase 4; MKK6: ...
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Mitogen-Activated Protein Kinase Kinase 2, a Novel E2-Interacting Protein, Promotes the Growth of Classical Swine Fever Virus via Attenuation of the JAK-STAT Signaling Pathway
... The mitogen-activated protein kinase kinase/extracellular regulated kinase (MEK1/2/ERK1/2) cascade is involved in the replica- tion of several members of the Flaviviridae family, ...
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Leptin signaling molecular actions and drug target in hepatocellular carcinoma
... [PI-3K]/protein kinase B [Akt], mitogen-activated protein kinase [MAPK]/extracellular regulated kinase 1 and 2 [ERK 1/2]), and noncanonical signaling pathways (AMPK, JNK, ...
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Identification of Top-ranked Proteins within a Directional Protein Interaction Network using the PageRank Algorithm: Applications in Humans and Plants
... cellular protein network can cause severe diseases in humans but can sometimes genetically improve plants, likely because growth is determinate in animals but indeterminate in ...reviews protein networks; ...
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