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Mixed disulfide

Pantethine and cystamine deplete cystine from cystinotic fibroblasts via efflux of cysteamine cysteine mixed disulfide

Pantethine and cystamine deplete cystine from cystinotic fibroblasts via efflux of cysteamine cysteine mixed disulfide

... its disulfide, cystamine, are equally effective in lowering cystine ...the mixed disulfide of cysteamine and cysteine in the lysosomes, which is then rapidly excreted from the ...of mixed ...

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A Structural Model of Pestivirus Erns Based on Disulfide Bond Connectivity and Homology Modeling Reveals an Extremely Rare Vicinal Disulfide

A Structural Model of Pestivirus Erns Based on Disulfide Bond Connectivity and Homology Modeling Reveals an Extremely Rare Vicinal Disulfide

... is BS-RNase, which belongs to the monomeric “pancreatic- type” family. The dimeric nature is crucial for the cytotoxic and immunosuppressive activity of BS-RNase. BS-RNase has evolved from pancreatic RNase A, and the ...

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Altered sulfhydryl reactivity of hemoglobins and red blood cell membranes in congenital heinz body hemolytic anemia

Altered sulfhydryl reactivity of hemoglobins and red blood cell membranes in congenital heinz body hemolytic anemia

... The mechanisms of hemoglobin precipitation into Heinz bodies and hemolytic anemia that characterize congenital Heinz body hemolytic anemia (CHBHA) were studied in patients with the unstable hemoglobins, Köln (b-98 valine ...

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The pathogenesis of coronary artery disease  A possible role for methionine metabolism

The pathogenesis of coronary artery disease A possible role for methionine metabolism

... vascular disease in infancy and childhood. Homocysteine is formed during the metabolism of methionine and accumulations of this and of cysteine-homocysteine mixed disulfide in the plasma indicate a partial ...

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CYSTINURIA: METABOLISM OF THE DISULFIDE OF CYSTEINE AND HOMOCYSTEINE

CYSTINURIA: METABOLISM OF THE DISULFIDE OF CYSTEINE AND HOMOCYSTEINE

... The study of renal extraction of amino acids helps to explain the difficulty in determining plasma concentrations despite large urinary excretion of the mixed disulfide.. The compound is[r] ...

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Allostery and Applications of the Lac Repressor

Allostery and Applications of the Lac Repressor

... Formation of mixed disulfide adducts at cysteine-281 of the lactose repressor protein affects operator and inducer binding parameters. Dimerisation mutants of Lac repressor[r] ...

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Thiol Disulfide Homeostasis in Patients with Panic Disorder

Thiol Disulfide Homeostasis in Patients with Panic Disorder

... and disulfide levels were measured in the patients with 40 PD patients and 40 healthy ...and disulfide levels were measured with a novel colorimetric, automated ...whereas disulfide/native thiol (p ...

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A PDI Family Network Acts Distinctly and Coordinately with ERp29 To Facilitate Polyomavirus Infection

A PDI Family Network Acts Distinctly and Coordinately with ERp29 To Facilitate Polyomavirus Infection

... five disulfide bonds within a pentamer (formed between C19 of one monomer and C114 of another monomer) are ...intramonomer disulfide bond within a subset of the monomers, causing a different mobility ...

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Atmospheric oxidation of carbon disulfide (CS2)

Atmospheric oxidation of carbon disulfide (CS2)

... formula) are in kJ/mol, activation enthalpies (values under/above each transition state). in kJ/mol and distances (values around chemical bonds) between atoms in Å.[r] ...

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Ferromagnetism in exfoliated tungsten disulfide nanosheets

Ferromagnetism in exfoliated tungsten disulfide nanosheets

... Two-dimensional-layered transition metal dichalcogenides nanosheets have attracted tremendous attention for their promising applications in spintronics because the atomic-thick nanosheets can not only enhance the ...

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Allium hookeri root extract exerts anti inflammatory effects by nuclear factor κB down regulation in lipopolysaccharide induced RAW264 7 cells

Allium hookeri root extract exerts anti inflammatory effects by nuclear factor κB down regulation in lipopolysaccharide induced RAW264 7 cells

... proteins [34, 35]. According to the pro-inflammatory stim- uli, IκB becomes phosphorylated, ubiquitinated, and then degraded. Thus, the liberated NF-κB dimers are translo- cated to nucleus, where the transcription of ...

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Improvement of Thermal Stability of DFPase by In silico Methods

Improvement of Thermal Stability of DFPase by In silico Methods

... Efficiency of enzymes which are used in industrial or environmental applications is highly dependent on their thermal stability. In this study, the stability of DFPase has been evaluated after introducing ...

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Identification and characterization of the protein disulfide isomerase multigene family in plants.

Identification and characterization of the protein disulfide isomerase multigene family in plants.

... The purpose of this review chapter is to provide basic background on PDIL1-1 and other members of the PDI gene family. In addition, new areas of PDI gene family research will be discussed. Numerous reports in yeast and ...

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1,28-Di[(cholest-5-en-3 -yl)disulfanyl]-4,25-dioxo-3,8,

1,28-Di[(cholest-5-en-3 -yl)disulfanyl]-4,25-dioxo-3,8,

... High transfection efficiency both in vitro and in vivo was demonstrated by a disulfide CA based.. 38.[r] ...

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Production of Iron Disulfide Nanoparticles by Hydrothermal Process

Production of Iron Disulfide Nanoparticles by Hydrothermal Process

... materials because of their fundamental importance as well as wide range of potential applications in nanodevices. Therefore, it is necessary to design a low-temperature synthesis route for solving these problems. ...

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Intercapsomeric Disulfide Bonds in Papillomavirus Assembly and Disassembly

Intercapsomeric Disulfide Bonds in Papillomavirus Assembly and Disassembly

... results, disulfide bonds were found to be critical for virion integrity, and their reduction led to a substantial conformational change in the capsid which may be a precursor state for disassembly in ...

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Alteration of Thiol-Disulfide Homeostasis in Fibromyalgia Syndrome

Alteration of Thiol-Disulfide Homeostasis in Fibromyalgia Syndrome

... and disulfide lev- els (µmol/L) were measured by the method which was de- veloped by Erel et ...(14) Disulfide/native thiol (DNT), di- sulfide/total thiol (DTT) and native thiol/total thiol (NTT) rates were ...

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Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins

Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins

... by disulfide bond scram- bling (6, 23, 24, ...by disulfide bond scrambling, we find that aberrant disul- fide bonds are present in a substantial proportion of nonnative gp140 proteins (possibly as high as ...

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Polymer synthesis and conjugation strategies for enhancing the stability of oxytocin

Polymer synthesis and conjugation strategies for enhancing the stability of oxytocin

... formed without the addition of a reducing agent..........................................................................90 Figure 2.36. RP-HPLC trace showing reappearance of oxytocin under reversible conditions, and bar ...

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Synthesis and charactyerization of formamidine disulfide schiff bases and their corresponding 1, 3 Oxazepines

Synthesis and charactyerization of formamidine disulfide schiff bases and their corresponding 1, 3 Oxazepines

... Two grams of formamidine disulfide (2) was dissolved in 5ml dilute methanol. 10ml of benzaldehyde (30) was then added into the solution in a conical flask and warm on a water bath for about 15minutes with ...

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