The multiscale approach was incorporated into ABMs to simulate GBM progression by incorporating into the model the interactions between different scales - the intracellu- lar (gene-protein interaction) and the cellular (including cell-cell interactions and phe- notypic switches e.g. from migration to proliferation and vice versa) - which in turn affect the spatio-temporal evolution of GBM (tissue scale). The relationships among the intracellular, cellular and tissue scales were conceptually defined as “ interfaces ” . As indicated in Figure 1: (a) A cell’s phenotype is defined as an interface between the intracellular and intercellular levels. The signaling pathway at intracellular level deter- mines the cell’s phenotype, which regulates intercellular behaviors. (b) We denote the diffusion of chemoattractants as an interface between the intercellular and tissue levels. At the tissue level, cells secrete chemoattractants that diffuse according to their con- centration gradients and remodel the microenvironment of the tumor. (c) A cell’s pathway receptors are defined as an interface between tissue and intracellular level. The paracrine or autocrine effects of chemoattractants on the tissue level are sensed by cellular receptors and trigger intracellular signaling pathways to determine a cell ’ s phenotype.
Asmaa Alsumait et al  introduced the Heuristic Evaluation for Child E-learning applications (HECE).HECE is a set of heuristics for child e-learning applications. Petri Nokelainen  in his paper presented pedagogical usability criteria for evaluating digital learning material. The following components, Learner control, Feedback, Added value, Learner activity, Motivation, Cooperative/Collaborative learning, Applicability and Goal orientation were focused in his work. Gavin Sim et al  reported the findings of an analysis of the relationship between fun, usability and learning in the educational software designed for the children. Walayat Hussain et al  has emphasized on how to make a webpage more usable in terms of readability for different age groups. The paper has focused on eight readability factors that are white space, graphics, line spacing, font style, text width, color contrast, headings, font size, and animation. Lisa Meloncon et al  presented a set of guidelines to aid the design process to develop educational websites for children.
This paper proposes a Java-based multi-participant 3D graphics application interface to provide 3D graphics and interactive capabilities over network. Two libraries support this interface, one is a 3D graphics library, called JavaGL, and the other is a network library, called JavaNL. The 3D graphics library is almost identical to OpenGL application interface but is written in Java to satisfy the 3D graphics requirement of the application model. The network library follows the concepts of Distributed Interactive Simulation (DIS), and is also written in Java. With these two libraries, we are able to provide an interactive application written in Java, gains the flexibility in cross-platform capability, while maintaining reasonable performance over Local Area Network (LAN).
The interface theory of cold fusion is a variant of Ion Band State (IBS) Theory. 1 It models Bloch symmetry deuterons in a 2-dimensional metal lattice instead of the 3-dimensional metal lattice first used. Both IBS variants recognize that the required lattice symmetry has limited extent, with the reactive deuterons being bound inside a closed volume like a box. The reactive deuterons are confined within classical turning point boundaries, while within the box their density distributions are modulated by a lattice array potential. Strictly speaking, the IBS fusion theory is a many-body theory. Nuclear dd fusion is one of several LENR processes. Some LENR processes do not require many-body ions and support room temperature nuclear reactions using light ions in single-particle Bloch geometry. For example, the decay of metastable single-body Bloch-function 8 Be seems to be the source of MeV alphas in Oriani's light/heavy water electrolysis, and in several co-deposition electrolysis CR39 studies, as described in ICCF14 Abstracts. 2 The Oriani MeV alphas are side products of both light water and heavy water electrolysis, using either Pd or Ni cathodes, as shown in highly repeatable tests. Bloch 8 Be is likely the nuclearly reactive component in the final step of the Iwamura et al. transmutation studies. 3 Despite differences, all LENR systems seem to share some essential physics.
Since triangles are processed in the order they are received from the geometry engine (in the case of Intel GMA 900, the triangles are received from the processor), many pixels are written over several times due to other pixels being closer to the viewers perspective. This redundant rendering is memory bandwidth intensive and can result in non-optimal graphics performance.
For GeForce-based GPUs with more than 2.75 GB of video memory, as well as all Quadro and Tesla GPUs, the NVIDIA display driver does not constrain TAG memory reporting. The disadvantage of constraining TAG on systems with larger amounts of video and system memory is that memory which otherwise would be available for graphics use is no longer available. Since shared system memory is limited first, driver components and algorithms utilizing shared system memory may suffer performance degradation when TAG is constrained.
To use the Quadro SDI Capture card, you need to install the NVIDIA WDM driver for the Quadro SDI Capture card after installing the Quadro professional driver. The WDM driver version must be from the same branch as the installed NVIDIA graphics driver. If at a later time you install a different Quadro professional driver version–for example, when upgrading from a Release 260 driver to a Release 265 driver–you must reinstall the WDM driver from the same driver branch as well– in this example, Release 265.
Thirty popular online shopping sites from three different countries (UK, US and Japan) were evaluated using this method. It was found that 87% of the sites were not accessible to the blind user . This result reveals that interface layout was not considered from the view point of blind users. Many applications fail to realize that a well-designed interface layout impacts positively the navigation process of a blind. The usage of the correct layout of blocks improves the accessibility features of an interface. An accessible interface layout allows blind users to travel around an application much faster and feel more satisfied. The findings of ,  and  interrelates real life environment in classifying objects as cues or obstacles in facilitating their navigation process as well as placing related topics closely could be combined to form a complete concept on interface layout. However, in the case of a cue turned into an obstacle or mislead of subtopics for certain users which could be due to influence of their past experience or interaction style was not given much thought in this research. This in return, might create a smooth navigational process only for specified users and might not be applicable for others.
PYMOL act as an important bioinformatic tool allowing to perform docking studies using autodock against drug discovery for lymphatic filariasis.The plugin covers all functionalities for the entire wtrorkflow of a docking run plus additional functionality to prepare, execute and analyze virtual screening tasks. Since visual support is an important aspect of structure-based drug design, the plugin is expected to enhance these efforts by allowing the combined use of two widely used docking programs and PYMOL. Docking of small molecule compounds of DEC and albendazole into the binding site of the receptor and estimating binding affinity of the complex is an important part of the mass drug administration design process. Docking helps in the production of compound of DEC with albendazole against Wuchereria bancrofti by identifying the molecular features and two improve the potency of the drug. PYMOL and molecular docking findings highlight the versatile tool in drug design efforts.
While attending RESFEST, an international digital film festival in Toronto, Canada, I was exposed to various aesthetic styles and concepts, as well as new techniques in production of motion graphics and digital video. What appealed to me the most was the extraordinary variety of visual and innovative ideas for experimental motion graphics, short films, commercials, music videos and animations. The works that drew the most amount of my attention were the pieces that had a strong emphasis on visual illusions. With their inventive and polished methods of creating transitional devices, this created new ideas for use in my own works.
The evaluation and decision component uses the data that are provided by the situation analytics component to decide whether an adaptation of the user interface is currently meaningful and necessary. For this purpose the component evaluates one or more applicable situation rules and has to solve possible conflicts between the rules. Whether an adaptation is meaningful depends on the predefined purpose of the situation-aware target application. Goals to meet can range from successful marketing activities in e-business, e.g. having the user buying an item from the e-shop or letting her or him browse through the latest special offers, to improved user experience levels, or to meeting user desires defined by the hidden mental states of the user.
Results. The article establishes links between the design parameters of the part drawing and tabular values of the variables. The revealed relationships between the parameters in the drawing and the variables in the table make it possible to change the geometric shape of the part by changing the values in the variable table, i.e. the drawing is managed through the table. It is proposed to use this system of work with the parametric drawing in computer-aided design systems for calculating the parameters of technological processes. Discussion and Conclusion. The tasks solved in this article allow making a step in increasing the level of automation of parameter calculations in computer-aided design systems. The implementation of the developed methodology for constructing mathematical models of parts based on graphic systems will increase the overall level of automation of developing geometric drawings of parts. The implementation of this technique in computer-aided de- sign systems allows automating the calculation of parameters (cutting modes, time norms, technological dimensions on transitions, etc.).
What is important to remember is that when designing for digital, the PPI will only have an incidence on how you perceive your design and on your work�ow and on pt sized graphics such as font. If you include in your work�ow source �les with various PPI con�gurations, the program will resize any transferred visual between the di�erent �les by the PPI ratio of the receiving �le. It will be come a problem for you.
Abstract: In this paper, a comparative study of software-based user authentication techniques, and also the use of traditional password techniques and PINs against numerous alternative methods involving graphical password schemes is made. In order to achieve authentication, all these methods depend upon the user‟s ability to recall some secret knowledge which forms the basis of these methods. Moderately comprehensive overview of various researchers‟ work in this regard, covering both usability and security aspects is then presented, highlighting novel features thereof. Keeping in mind, the security threats that various graphical or otherwise password schemes may suffer from, attention is drawn to the latest attempts which include odour based password, pass films and demographic maps.
The object is the underlying concept in an object-oriented system. It may be defined as "a package of information and a descrip tion of its manipulation" [Robson 1981]. In this way, an object repre sents both data and the computational processes which manipulate this data. The information in an object is altered by sending a message to that object. The content of the message determines which object proce sses are invoked and thus the information to be updated. In an object- oriented graphics system, objects are used to structure images on a display. Each object is responsible for a single image and is al located a portion of the display surface. The object may have an af fect on the display screen only within this allocated area. These object-oriented systems support a small number of graphical primitives that are used to directly alter a raster display. [Green 1982a].
Payment channel model enables defining a commission for each product in the payment channel. The channel can calculate the commission according to any defined formula. The formula is defined in the contract between Paytrail and the channel. Payment channel has to follow the formula defined in the contract.!