Molecular Biomarkers
Association between changes in molecular biomarkers of cartilage matrix turnover and changes in knee articular cartilage: a longitudinal pilot study
... While the progression of OA may be driven by cartil- age factors in some patients, it may be driven by bone or inflammation associated factors in others (Buttgereit et al., 2015). Metabolic alterations in joint tissues ...
10
Molecular Biomarkers of Pancreatic Intraepithelial Neoplasia and Their Implications in Early Diagnosis and Therapeutic Intervention of Pancreatic Cancer
... of molecular changes in the progression from PanIN to PDAC with the establishment of genetically modified animal models that recapitulate these changes ...Such molecular alterations provide a road map for ...
10
Sudden Cardiac Death (SCD) – risk stratification and prediction with molecular biomarkers
... different molecular biomarkers that are used for early detection of ...genetic biomarkers, where the majority of them are genomic variants for genes that encode for ion ...protein biomarkers ...
12
Molecular biomarkers in multiple sclerosis
... Molecular biomarkers enable individual decisions and are an important step on the way to a personalized ther- apy [3, ...successes, biomarkers that enable a reliable prediction of the therapy ...
11
Molecular biomarkers and regulators of susceptibility to drug induced kidney injury
... standard biomarkers of kidney injury include Serum Creatinine and blood urea ...suboptimal biomarkers of kidney injury in terms of sensitivity and specificity so there is a real need for the development of ...
261
Blood-based molecular biomarkers for Alzheimer’s disease
... Measuring biomarkers for brain diseases in the blood poses a number of challenges that demand sensitive and specific assays and careful validation ...Brain-derived biomarkers are typically present at ...
7
Molecular biomarkers screened by next generation RNA sequencing for non sentinel lymph node status prediction in breast cancer patients with metastatic sentinel lymph nodes
... in their NSLN, ALND in these patients remains contro- versial [10, 11]. In order to avoid the physical discomfort and potential complications associated with ALND in these patients, an effective method to predict the ...
10
IDENTIFICATION OF NEW MOLECULAR BIOMARKERS - PROTEOMICS
... revealed that human growth hormone (hGH) is of great importance in the progression of this disease. Namely, growth hormone can be one of the main drivers of the metastasis process. By coagulating the breast carcino- ma ...
9
Castration-Resistant Prostate Cancer Tissue Acquisition From Bone Metastases for Molecular Analyses.
... Prostate cancer is currently the second most common cancer in men, accounting for 15% of male cancer cases. Prostate cancer is the fifth leading cause of death in men worldwide (6.6% of total deaths) and is a major cause ...
9
LncRNAs: From Basic Research to Medical Application
... as molecular biomarkers or therapy strategies in human cancer and cardiovascular ...function, molecular interaction, and bioinformatics ...as biomarkers or therapy targets and effectively ...
13
Consumption coagulopathy in acute aortic dissection: principles of management
... In this study, we analyzed several molecular biomarkers of the coagulation system and platelet function using ELISA and we analyzed clotting factors, platelet function and fibrinogen fun[r] ...
8
Exploring the effects of Acceptance and Commitment Therapy (ACT) on biomarkers of stress in breast cancer survivors
... and molecular biomarkers of stress in breast cancer survivors using a randomised, controlled clinical trial ...and molecular biomarkers assessed included fasting blood glucose levels, relative ...
95
Download Download PDF
... specific molecular biomarkers in the prefrontal cortical regions of these groups revealed several striking similarities to findings in human schizophrenia ...
5
Triple-negative (ER, PgR, HER-2/neu) breast cancer in Indian women
... Patients who were diagnosed with breast cancer and underwent curative surgery at Grant Medical College and Sir JJ Group of Hospitals, Mumbai, India, from May 2007 to October 2010 were included in the study. The inclusion ...
11
Original Article Clinical characteristics and types of EGFR gene mutations in patients with synchronous primary lung cancer
... lesions, molecular biomarkers, and associated mutations in epidermal growth factor receptor (EGFR) in ...characteristics, molecular biomarkers, and gene mutations was ...these ...
9
Breast cancer chemoprevention: beyond tamoxifen
... target molecular abnormalities found in estrogen receptor (ER)-negative and/or ER-positive precancerous breast tissue and have side effect profiles that differ from ...and molecular biomarkers to ...
5
MicroRNAs as biomarkers in molecular diagnosis of refractory epilepsy
... function as main causes of DRE. Diseases including West syndrome, Lennox-Gastaut syndrome and tuber- ous sclerosis could assist in identifying DRE [6]. More- over, temporal lobe epilepsy (TLE) represents the most common ...
6
Application of Molecular Biological Biomarkers to Endocrine Disruption Studies
... tests. Molecular biomarkers provide an innovative technique for the screening and research of ...the molecular endpoints in aromatase inhibitors, hormone levels and expressions of various ...the ...
5
Weathering of Petroleum Biomarkers: Review in Tropical Marine Environment Impacts
... Assessment, monitoring, and modeling of weathering processes associated with petroleum biomarkers are im- portant tools for geochemistry of petroleum and environment. This allows predicting, with relative ...
13
The construction and analysis of ceRNA networks in invasive breast cancer: a study based on The Cancer Genome Atlas
... of functional annotation tools for investigators to understand the biological meaning behind Gene Ontology (GO) and the Kyoto Encyclopedia list of genes. To further understand the function of these differentially ...
11