Monoamine oxidase A
Systemic lipopolysaccharide-mediated alteration of cortical neuromodulation involves increases in monoamine oxidase-A and acetylcholinesterase activity
... mation. Monoamine oxidase-A (MAO-A; breakdown nor- epinephrine and serotonin) expression has been widely shown to increase in response to chronic stress [18], glu- cocorticoids [19,20] and inflammatory p38 ...
11
Prenatal iron deficiency and monoamine oxidase A (MAOA) polymorphisms: combined risk for later cognitive performance in rhesus monkeys
... research, monoamine oxidase A (MAOA) gene polymor- phisms in humans appear to interact with adverse child- hood environments to permanently alter behavior in ways that are important to social and affective ...
9
Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis
... Tumors from patients with high-grade aggressive prostate cancer (PCa) exhibit increased expression of monoamine oxidase A (MAOA), a mitochondrial enzyme that degrades monoamine neurotransmitters and ...
19
Calcium ions alter monoamine oxidase A activity
... of monoamine oxidase-A contributes to the production of peroxyradicals in hippocampal cultures: implications for Alzheimer disease-related pathology BMC Neuroscience 8, ...
5
Testing for association of the monoamine oxidase A promoter polymorphism with brain structure volumes in both autism and the fragile X syndrome
... We have previously investigated relationships between genes of the serotonin system, including monoamine oxidase A (MAOA), and the associated trait of brain morphology in children with autism. Abnormalities ...
9
Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells
... Monoamine oxidase A (MAO-A) is a mitochondrial enzyme that degrades monoamine neurotransmitters including 5-hydroxytryptamine (5-HT, or serotonin) and norepinephrine ...
15
Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells
... Background: Breast tumor growth and recurrence are driven by an infrequent population of breast tumor-initiating cells (BTIC). We and others have reported that the frequency of BTIC is orders of magnitude higher when ...
13
The role of the <em>monoamine oxidase A</em> gene in moderating the response to adversity and associated antisocial behavior: a review
... Our aim in the present paper is to provide an update of studies on the monoamine oxidase A (MAOA) gene as a moderator of adversity-induced antisocial behavior (ASB). After a brief introduction of some key ...
16
ASSOCIATION BETWEEN MONOAMINE OXIDASE A (MAOA) GENE POLYMORPHISM AND VIOLENT BEHAVIOR
... Practical portrayal thinks about uncovered that transcriptional action of the human monoamine oxidase A (MAOA) quality is balanced by a polymorphic redundant arrangement situated in 1.2 kb upstream of the ...
6
Ciproxifan, a H3 receptor inverse agonist, reversibly inhibits human monoamine oxidase A and B
... rat monoamine oxidases with slight preference for monoamine oxidase B in both ...and monoamine oxidases are all capable of affecting neurotransmitter modulation in brain, we consider dual ...
6
Kinetic analysis of [11C]befloxatone in the human brain, a selective radioligand to image monoamine oxidase A
... Seven healthy, nonsmoker, male volunteers (72 ± 9.5 kg, age 26 ± 4.5 years) from a previous clinical protocol were included in this study [7]. All subjects were free of current medical or psychiatric illnesses and had no ...
9
Polymorphisms in the canine monoamine oxidase a (MAOA) gene: identification and variation among five broad dog breed groups
... In order to study MAOA genetic diversity in dogs, we designed a preliminary study whose objectives were to identify novel alleles in functionally important regions of the canine MAOA gen[r] ...
8
Pharmacophore modeling and atom based 3D QSAR studies of tricyclic selective monoamine oxidase A inhibitors
... 854 Available online at www derpharmachemica com Scholars Research Library Der Pharma Chemica, 2010, 2(6) 171 182 (http //derpharmachemica com/archive html) ISSN 0975 413X 171 www scholarsresearchlibr[.] ...
12
Serum Monoamine Oxidase (A and B) Activities and Oxidative Stress Status in Iraqi Infertile Women Undergoing In Vitro Fertilization
... Serum monoamine oxidase (MAO-A and B) activities were measured in 98 infertile women undergoing in vitro fertilization (Intracytoplasmic Sperm Injection ICSI) attending Kamal AL-Samaree Hospital for ...
7
Molecular docking studies of coumarin hybrids as potential acetylcholinesterase, butyrylcholinesterase, monoamine oxidase A/B and β-amyloid inhibitors for Alzheimer’s disease
... [8–10]. Monoamine oxidase B (MAO-B) is an important factor that is involved in oxidative stress and oxidative stress is said to be among the multiple factors, which induce the ...
57
Amphetamine manipulates monoamine oxidase-A level and behavior using theranostic aptamers of transcription factors AP-1/NF-kB
... Amphetamine exposure induces elevations in immediate early genes and their products; however, the relationship of such changes in gene expression to amphetamine in- duced restless activi[r] ...
8
SCAFFOLD BASED DESIGNING OF NOVEL 1, 3-DIOXOL DERIVATIVES AS MONOAMINE OXIDASE INHIBITOR: IN SILICO APPROACH
... Various 1,3-dioxol derivatives were designed by using computational methods and synthesized to explore their monoamine oxidase A inhibitory activity. The QSAR properties of synthesized compounds were ...
7
Identification of potential monoamine oxidase inhibitor from herbal source for the treatment of major depressive disorder: An in silico screening approach
... Various computational tools and software’s are used to analyze the protein MAO-A structure and to study the binding energy properties with Arecoline,Apigenin, Curcumin ,Kaempferol ,Luteolin ,Quercetin ,Brofaromine . ...
11
Efficacy, safety, and patient preference of monoamine oxidase B inhibitors in the treatment of Parkinson's disease
... Abstract: Parkinson’s disease (PD) is the second most common neurodegenerative disease and the most treatable. Treatment of PD is symptomatic and generally focuses on the replacement or augmentation of levodopa. A number ...
8
Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels
... MAO-B: Monoamine oxidase B; MOI: Multiplicity of infection; MS: Mass spectrometry; NGS: Normal goat serum; NICD: Notch intracellular domain; NMDAr: N-methyl- D -aspartate receptor; PBS: Phosphate- buffered ...
19