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monoclonal anti-CD3 antibodies

A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis

A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis

... bilized anti-CD3 and anti-CD28 monoclonal antibodies (anti-CD3/anti-CD28; Dynabeads Human T-Activator, Invitrogen, Grand Island, NY, USA); bacterial CpG oli- ...

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Anti-CD19 Monoclonal Antibodies: a New Approach to Lymphoma Therapy

Anti-CD19 Monoclonal Antibodies: a New Approach to Lymphoma Therapy

... (11), anti CD19 monoclonal antibodies (mAbs) have lately been advanced into clinical ...Many anti-CD19 IgG1 antibodies with cytotoxicity-improved Fcγ part and three drug conjugated ...

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MicroRNA expression profiles in human CD3+ T cells following stimulation with anti human CD3 antibodies

MicroRNA expression profiles in human CD3+ T cells following stimulation with anti human CD3 antibodies

... Background: Anti-CD3 therapy can induce immunosuppression by several non mutually exclusive mechanisms that have been proposed to explain the therapeutic effect the administration anti-CD3 ...

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Activation of T lymphocytes by immobilized monoclonal antibodies to CD3  Regulatory influences of monoclonal antibodies to additional T cell surface determinants

Activation of T lymphocytes by immobilized monoclonal antibodies to CD3 Regulatory influences of monoclonal antibodies to additional T cell surface determinants

... to CD3 and class I MHC molecules but not CD2, LFA-1 or CD4 were immobilized to separate ...when anti-CD3 stimulation is suboptimal, responses can be enhanced by MAb to CD5 or CD28 (Tp44) or by ...

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Matrix metalloproteinase-13 refines pathological staging of precancerous colorectal lesions

Matrix metalloproteinase-13 refines pathological staging of precancerous colorectal lesions

... specific antibodies for detection of MMP-13 (1:100, goat anti MMP-13 polyclonal IgG, R&D Systems, Minneapolis, USA) and suitable secondary antibodies (Impress Reagent Kit anti-goat-Ig ...

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Selective Accumulation of Th2-skewing Immature Erythroid Cells in Developing Neonatal Mouse Spleen

Selective Accumulation of Th2-skewing Immature Erythroid Cells in Developing Neonatal Mouse Spleen

... and anti-CD28 monoclonal antibodies (Abs) in the absence or presence of purified immature erythroid cells (nucleated Ter119 + cells) from spleen of ...

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Detection of human immunodeficiency virus type 1-specific memory cytotoxic T lymphocytes in freshly donated and frozen-thawed peripheral blood mononuclear cells.

Detection of human immunodeficiency virus type 1-specific memory cytotoxic T lymphocytes in freshly donated and frozen-thawed peripheral blood mononuclear cells.

... Target cells and recombinant VV. The target cells were autologous B-LCL immortalized by infection with Epstein-Barr virus (EBV) (filtered supernatant from the EBV-transformed B95-8 marmoset cell line; American Type ...

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Severe inhibition of lipooligosaccharide synthesis induces TLR2-dependent elimination of Mycobacterium marinum from THP1-derived macrophages

Severe inhibition of lipooligosaccharide synthesis induces TLR2-dependent elimination of Mycobacterium marinum from THP1-derived macrophages

... TLR2 and CR3 are important cell surface recogni- tion receptors for mycobacteria [6]; therefore, we next assessed the contribution of CR3 and TLR2 in the phago- cytosis of the M. marinum strains. Macrophages were first ...

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The heterodimeric association between the membrane proteins of Semliki Forest virus changes its sensitivity to low pH during virus maturation.

The heterodimeric association between the membrane proteins of Semliki Forest virus changes its sensitivity to low pH during virus maturation.

... In the present work we have used coprecipitation analyses with anti-El and anti-E2 monoclonal antibodies and sedimentation analyses in sucrose gradients to demonstrate that i the intrace[r] ...

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Production and Evaluation of Specific Single-Chain Antibodies against CTLA-4 for  Cancer-Targeted Therapy

Production and Evaluation of Specific Single-Chain Antibodies against CTLA-4 for Cancer-Targeted Therapy

... (30). Monoclonal antibody treatment offers improved results compared to previous methods, but some disadvantages and rejection in humans has limited their clinical use (31, ...

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Plasmapheresis, Anti-ACE2 and Anti-FcγRII Monoclonal Antibodies: A Possible Treatment for Severe Cases of COVID-19

<p>Plasmapheresis, Anti-ACE2 and Anti-Fc&gamma;RII Monoclonal Antibodies: A Possible Treatment for Severe Cases of COVID-19</p>

... The risk for activation/inhibition of angiotensin-convert- ing enzyme 2 must be acceptable. Because we are aiming the 3-dimensional extracellular structure of ACE2 to prevent the virus usage of it, and typically, it ...

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Monoclonal antibody based sandwich enzyme linked immunosorbent assay for detection of Bordetella pertussis filamentous hemagglutinin

Monoclonal antibody based sandwich enzyme linked immunosorbent assay for detection of Bordetella pertussis filamentous hemagglutinin

... Monoclonal antibody 16-2-D9 and biotinylated monoclonal antibody 15-2-A5 A and polyclonal goat anti-FHA serum and monoclonal antibody 16-1-E3 B were used as capture and second antibodies[r] ...

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In vivo effects of IgA and IgG2a anti CD3 isotype switch variants

In vivo effects of IgA and IgG2a anti CD3 isotype switch variants

... increased significantly at 3 h after T3.G2a, but not after T3.A. The TNF peak level occurring at 1 h after T3.A was much lower than after T3.G2a. In plasma, complement and neutrophil activation products only increased ...

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Trypanosoma cruzi Bromodomain Factor 3 Binds Acetylated α-Tubulin and Concentrates in the Flagellum during Metacyclogenesis

Trypanosoma cruzi Bromodomain Factor 3 Binds Acetylated α-Tubulin and Concentrates in the Flagellum during Metacyclogenesis

... Bromodomains are highly conserved acetyl-lysine binding domains found mainly in proteins associated with chromatin and nuclear acetyltransferases. The Trypanosoma cruzi genome encodes at least four bromodomain factors ...

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Therapeutic treatment of New Zealand mouse disease by a limited number of anti idiotypic antibodies conjugated with neocarzinostatin

Therapeutic treatment of New Zealand mouse disease by a limited number of anti idiotypic antibodies conjugated with neocarzinostatin

... of anti-Id antibodies conjugated with NCS brought about an improvement in the survival rate of female NZB/W F1 ...of anti-DNA-producing cells. The suppression of anti-DNA antibody synthesis ...

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Anti CTLA4 monoclonal antibodies: the past and the future in clinical application

Anti CTLA4 monoclonal antibodies: the past and the future in clinical application

... testing anti-CTLA-4 antibodies (ipilimumab and tremelimumab) for the treatment of melanoma to focus on practical or scientific questions related to the broad utilization of these products in the ...

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Protective anti-reovirus monoclonal antibodies and their effects on viral pathogenesis.

Protective anti-reovirus monoclonal antibodies and their effects on viral pathogenesis.

... We now report that i MAbs specific for each of the reovirus outer capsid proteins and the core spike protein are protective under certain circumstances, ii MAb protection does not univer[r] ...

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Molecular properties of human monoclonal anti-DNA and antiphospholipid antibodies

Molecular properties of human monoclonal anti-DNA and antiphospholipid antibodies

... The major drawbacks of bacterial expression of eukaryotic proteins are that post-translational modifications such as glycosylation are absent and that the molecules may not be folded properly. This applies particularly ...

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Antibodies against C-Reactive Protein Cross-React with 60-Kilodalton Heat Shock Proteins

Antibodies against C-Reactive Protein Cross-React with 60-Kilodalton Heat Shock Proteins

... and monoclonal (CRP-8) anti-CRP antibodies on human ...that antibodies specific for Hsp60 are present in the anti-CRP antibody prep- ...for monoclonal antibodies against ...

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Interactions of CD4+ and CD8+ human T lymphocytes from malaria unprimed donors with Plasmodium falciparum schizont stage

Interactions of CD4+ and CD8+ human T lymphocytes from malaria unprimed donors with Plasmodium falciparum schizont stage

... Monoclonal antibodies to CD3 or the aji-chain T-cell receptor blocked cloned T-cell responses to the schizont extract, and although the responses of the majority of the CD4+ or CD8+ T-ce[r] ...

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