monoclonal antibody (IgG 2a, anti-T3)
Anti tumor activity and toxicokinetics analysis of MGAH22, an anti HER2 monoclonal antibody with enhanced Fcγ receptor binding properties
... the monoclonal antibody (mAb) trastuzumab ...direct anti-proliferative activity, antibody-dependent cell-mediated cytotoxicity (ADCC), and presentation of antigenic determinants of opsonized ...
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Original Article Improved lung cancer classification using new optimized immunohistochemical assay with anti-p40 (BC28) mouse monoclonal antibody
... using anti- p40 (BC28) antibody was developed at Ventana Medical Systems, ...primary antibody incubation for 16 min- utes. Final concentration of the anti-p40 (BC28) antibody was ...
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Monoclonal antibody based sandwich enzyme linked immunosorbent assay for detection of Bordetella pertussis filamentous hemagglutinin
... Monoclonal antibody 16-2-D9 and biotinylated monoclonal antibody 15-2-A5 A and polyclonal goat anti-FHA serum and monoclonal antibody 16-1-E3 B were used as capture and second antibodies[r] ...
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Induction of IgG antibodies against GD3 ganglioside in rabbits by an anti idiotypic monoclonal antibody
... Anti-idiotypic MAb were raised in syngeneic mice against a mouse MAb recognizing GD3 ganglioside (MAb R24). Two anti-idiotypic MAb, designated BEC2 and BEC3, recognized distinct determinants on MAb R24 that ...
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Generation of a monoclonal antibody against the glycosylphosphatidylinositol-linked protein Rae-1 using genetically engineered tumor cells
... (Figure 2A). The mAb we se- lected, 52A anti-Rae-1, can bind Rae-1ε, which was used to engineer the CT26 cell line, as well as Rae-1β, whose recombinant protein was used for Western blot ...this ...
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Recombinant neuraminidase pseudotyped baculovirus: a dual vector for delivery of Angiotensin II peptides and DNA vaccine
... Recombinant neuraminidase-AngII pseudotyped bacu- lovirus had been shown to successfully display AngII peptides on its surface for effectively presenting these peptide antigens to the immune system. This rBV-NA- AngII ...
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Ofatumumab: a novel monoclonal anti-CD20 antibody
... humanized monoclonal anti-CD20 antibody, was recently approved by the FDA for the treatment of fludarabine and alemtuzumab refractory chronic lym- phocytic leukemia ...mediates ...
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Minute Virus of Mice NS1 Interacts with the SMN Protein, and They Colocalize in Novel Nuclear Bodies Induced by Parvovirus Infection
... (primary antibody: anti-NS1 polyclonal; secondary antibody: anti-rabbit FITC conjugate) and VP1 (primary antibody: anti-VP1 polyclonal peptide antibody; secondary ...
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Evaluation of the Antitumor Activity of Dacomitinib in Models of Human Bladder Cancer
... oclonal antibody), trastuzumab (anti- HER2 monoclonal antibody) and lapatinib (dual anti-EGFR/HER2 tyro- sine kinase inhibitor) in UM-UC-6 cells, we found that a single treatment of 2 ...
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Absence of antigenic diversity in Pf155, a major parasite antigen in membranes of erythrocytes infected with Plasmodium falciparum
... b A is Liberian donor A; IgG was affinity purified on F32-infected erythrocytes; 33G2 is human monoclonal antibody IgM; MoMAb, is mouse monoclonal antibody IgGl against synthetic octapep[r] ...
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The performance of different pre-treatment techniques in the isolation and purification of monoclonal IgG antibody
... experiment, monoclonal antibody IgG1 crude sample supernatant was directly subjected to Hi-Trap Protein G affinity ...The IgG fractions were collected and analyzed by reducing SDS-PAGE for purity ...
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Errors in data interpretation from genetic variation of human analytes
... in antibody reagents has recently been established to be a central part of the crisis, present at a higher level than previously ...of monoclonal antibody technologies, poly- clonal antisera was the ...
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Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220.
... To study whether this inhibition of 2A activity has an effect on the cleavage of p220, we translated pMN30 RNA in vitro in the presence of increasing concentrations of anti-2A IgG and in[r] ...
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A novel function of the herpes simplex virus type 1 Fc receptor: participation in bipolar bridging of antiviral immunoglobulin G.
... We demonstrate that various immune IgG antibodies, including polyclonal rabbit antibodies to HSV-1 glycoproteins gCl and gDl and monoclonal human antibody to gDl blocked rosetting of IgG[r] ...
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Roles of apolipoproteins B and E in the cellular binding of very low density lipoproteins
... Two monoclonal anti-LDL-apo B antibodies (464B1B3 and 464B1B6, 2a and 2b, respectively) and two anti-apo E antibodies (1506 ...antibodies 2a or 2b or the antigen-binding fragments of ...
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Anti Ia Reactivity in Sera from Patients with Systemic Lupus Erythematosus
... and anti-Ia hybridoma antibodies ...with monoclonal Abs. Binding by specific monoclonal Abs was assessed by two methods: rosetting with ox erythrocytes conjugated with goat anti-mouse ...
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MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated
... the antibody re- sponse to rrNF cross-reacts with another member of the Ig superfamily, TAG-1, a recently identified target in MS, which elicits an encephalitogenic T cell re- sponse selectively targeting gray ...
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ATM protein is deficient in over 40% of lung adenocarcinomas
... commercial antibody (ab32420) for the identification of ATM by immunohistochemistry and estimate that 61 of 147 (41%, 95% CI 34%-50%) cases of lung adenocarcinoma are negative for ATM protein ...
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Healthy subjects produce both anti factor VIII and specific anti idiotypic antibodies
... FVIII. Antibody specificity was confirmed by the capacity to recognize soluble and insolubilized FVIII and to neutralize FVIII cofactor activity in FX ...one antibody preparation to the other. Sera or ...
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Quantitative immunology of immune hemolytic anemia: I The fixation of C1 by autoimmune antibody and heterologous anti IgG antibody
... rabbit IgG anti-IgG were required to fix a single molecule of C[unk]1, whereas only one molecule of goat IgM anti-IgG was ...isoimmune antibody molecules attached to the red ...
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