Mouse T cells and dendritic cells
Antigen processing and T cell priming by mouse dendritic cells
... BALB/c dendritic cells ...control cells of one mouse strain but not in the other; representing strain-specific genes expressed independently of ...
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Role of dendritic cells in the induction of regulatory T cells
... CD8a + DCs were initially identified in the mouse spleen with a propensity to drive iTreg induction [64]. A unique CD8 + splenic DC subset, which expresses DEC205, a type I transmembrane protein with multiple ...
10
Trichinella spiralis paramyosin activates mouse bone marrow derived dendritic cells and induces regulatory T cells
... However, the relationship between the Treg and Th17 responses in T. spiralis infection remains unclear. Together with our previous studies, our results further suggest the immunomodulatory function of T. ...
11
Interactions between dendritic cells and CD4+ T cells during Plasmodium infection
... a mouse malaria model, the interactions of DCs and naïve CD4 + T cells have been ...+ T cells and do not induce T cell ...effective T cell activation of naïve CD4 + ...
11
Type-specific dendritic integration in mouse retinal ganglion cells
... and dendritic RFs became increasingly non- overlapping, with minimal offset between recording site and respective RF ...different dendritic branches was only moderately ...independent dendritic ...
16
Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation
... cannot be applied. Instead, we used the following scanning window approach for defining regions with significantly high number of aligned TSS-seq reads. The number of TSS-seq reads mapped to the genome in windows of size ...
15
Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation
... Here, we present a large-scale study of short-term changes in histone modifications in mouse DCs during the response to LPS. We focused on the timing of increases in histone modifications at promoters and ...
16
Cells of the synovium in rheumatoid arthritis Dendritic cells
... autoreactive T cells into the periphery, where subsequent genetic or environmental proinflammatory events more readily trigger the priming of these T cells and the development of autoimmune ...
12
Dendritic cells fused with different pancreatic carcinoma cells induce different T-cell responses
... tumor cells or surface antigens expressed weakly on the cell surface of tumor ...+ T cells by PGE 2 secreted from carcinoma cells and the present study revealed that PGE 2 was secreted to a ...
12
Isolation of T cells from mouse oral tissues
... yields cells that show inconsistent viability and recovery (Figure 1A, top, ...one mouse ex vivo from mouse oral tissues, compared to 5 - 6 × 10 6 mouse gut intra- epithelial and lamina ...
7
Preferential Infection of Mature Dendritic Cells by Mouse Hepatitis Virus Strain JHM
... After syncytium formation, DCs are unlikely to function nor- mally. Development of the anti-MHV immune response would be compromised if large numbers of DCs were similarly in- fected in mice. Infection with virulent ...
9
Critical Role of Dendritic Cells in Mouse Mammary Tumor Virus In Vivo Infection
... to T cells, and serve as a reservoir of ...stimulate T- or B-cell proliferation, thereby fa- cilitating the transfer of virus to other cell types in which replication is more ...
9
The Change of Immunoactivity of Dendritic Cells Induced by Mouse 4 1BBL Recombinant Adenovirus
... In this study, we further confirmed the expression of 4- 1BB on DC, and the 4-1BB molecules expressed on DC were functional to active DC. Our results were consistent with previous reports, 9 which showed that the ...
5
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
... + dendritic cells might vary according to the conditions of infection and the route of ...+ dendritic cells collected from mice during the incubation period are able to carry the infection ...
7
Mucosal and systemic anti HIV immunity controlled by A20 in mouse dendritic cells
... 1 Department of Molecular Microbiology and Immunology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA. 2 Center for Cell and Gene Therapy, Baylor College of Medicine, ...
14
Effective Chemokine Secretion by Dendritic Cells and Expansion of Cross-Presenting CD4−/CD8+ Dendritic Cells Define a Protective Phenotype in the Mouse Model of Coxsackievirus Myocarditis
... Similar to the SARS coronavirus model, we found an induc- tion of proinflammatory cytokines in CVB3-infected mice al- beit with rather low levels of IL-6 and TNF- ␣ secretion by splenic DCs at various times ...
12
Viruses, dendritic cells and the lung
... the T lym- phocyte response to viral infection. In this mouse model of autoimmune diabetes the LCMV nucleoprotein is expressed in the β -cells of the pancreas, and destruction of the pancreas can be ...
5
Immunologists getting nervous: neuropeptides, dendritic cells and T cell activation
... as T helper cell differentiation, tolerance induction and lympho- cyte ...knockout mouse strains lacking particular neu- ropeptides or their receptors ...human T cell-mediated diseases awaits the ...
6
Dendritic epidermal T cells regulate skin antimicrobial barrier function
... Acknowledgments We thank Yoichiro Iwakura and Klaus Ley for providing Il17a –/– mice; Julie Jameson, Charles Surh, and Karsten Sauer for advice; Kitty Cheung and Kwesi Frimpong-Boateng for help with mouse ...
12
mTOR inhibitors effects on regulatory T cells and on dendritic cells
... immunosuppressive drugs such as mTOR inhibitors. Nevertheless, after 10 years of clinical experience mTOR inhibitors are still far to be positioned as a first-line immunosuppression in organ transplantation. Unex- ...
9