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Mucoadhesive sustained release

Mucoadhesive Sustained Release Formulation of Lamivudine

Mucoadhesive Sustained Release Formulation of Lamivudine

... the mucoadhesive sustained release formulations of ...two mucoadhesive formulations- gels and tablets were prepared by using three different polymers: HPMC K15, poloxamer 407 & carbopol ...

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FORMUALTION AND DEVELOPMENT OF MUCOADHESIVE SUSTAINED RELEASE BUCCAL TABLETS AND PATCHES OF 5 FLUOROURACIL USING DIFFERENT POLYMERS

FORMUALTION AND DEVELOPMENT OF MUCOADHESIVE SUSTAINED RELEASE BUCCAL TABLETS AND PATCHES OF 5 FLUOROURACIL USING DIFFERENT POLYMERS

... The ex vivo mucoadhesion time studies were performed after application of tablet and patch, respectively, on freshly cut goat stomach mucosa. The mucosa was fixed on a glass slide using double-sided adhesive, and one ...

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Development of Mucoadhesive Sustained Release Matrix Tablets of Methimazole for Oral Delivery

Development of Mucoadhesive Sustained Release Matrix Tablets of Methimazole for Oral Delivery

... develop sustained release matrix tablets containing ...drug release and stability ...drug release by both mechanism diffusion and ...the release rate of methimazole in matrix tablets ...

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Manju Shri*, Monika Sachdeva, Meenakshi Bajpai

Manju Shri*, Monika Sachdeva, Meenakshi Bajpai

... natural mucoadhesive polymer from natural source (Date Palm) & formulation and evaluation of gastro mucoadhesive Sustained release matrix ...of Mucoadhesive drug delivery system of ...

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Formulation and evaluation sustained release mucoadhesive gastroretentive pantoprazole sodium sesquihydrate tablets for anti–ulcer

Formulation and evaluation sustained release mucoadhesive gastroretentive pantoprazole sodium sesquihydrate tablets for anti–ulcer

... the mucoadhesive tablets of pantoprazole sodium sesquihydrate as a model drug whose half-life is ...1hour. Mucoadhesive sustained release systems increase the effectiveness of drug by ...

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 ENHANCEMENT OF ANTIMICROBIAL ACTIVITY OF SUPPRESS RELEASE AMOXICILLIN CAMPHOR COMPLEXED MUCOADHESIVE TABLETS BY STATISTICAL EXPERIMENTAL DESIGN

 ENHANCEMENT OF ANTIMICROBIAL ACTIVITY OF SUPPRESS RELEASE AMOXICILLIN CAMPHOR COMPLEXED MUCOADHESIVE TABLETS BY STATISTICAL EXPERIMENTAL DESIGN

... The sustained release of amoxicillin could be formulated in various forms, ...controlled release formulations as a mucoadhesive polymer for sustaining the drug ...amoxicillin ...

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A Mucoadhesive Bilayer Tablets for the Management of Type-II Diabetes Mellitus

A Mucoadhesive Bilayer Tablets for the Management of Type-II Diabetes Mellitus

... modified release drug delivery systems. A mucoadhesive controlled release device can improve the effectiveness of drug by helping to maintain a drug concentration between the effective and toxic ...

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FORMULATION, DEVELOPMENT AND STANDARDIZATION OF AN AYURVEDIC MUCO-ADHESIVE EXTENDED RELEASE VAGINAL TABLET

FORMULATION, DEVELOPMENT AND STANDARDIZATION OF AN AYURVEDIC MUCO-ADHESIVE EXTENDED RELEASE VAGINAL TABLET

... three mucoadhesive vaginal formulations, ...developing mucoadhesive action with the active drug ...and mucoadhesive force of ...standard mucoadhesive sustained release herbal ...

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PREPARE AND EVALUATE MUCOADHESIVE FORMULATIONS OF LAMIVUDINE WITH BETTER CONTROLLED/ SUSTAINED DRUG RELEASE PROFILE

PREPARE AND EVALUATE MUCOADHESIVE FORMULATIONS OF LAMIVUDINE WITH BETTER CONTROLLED/ SUSTAINED DRUG RELEASE PROFILE

... the mucoadhesive sustained release formulations of lamivudine and to fulfill this aim, two mucoadhesive formulations Gels and Tablets were prepared by using three different polymers: HPMC K15, ...

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Clarithromycin based oral sustained release nanoparticulate drug delivery system

Clarithromycin based oral sustained release nanoparticulate drug delivery system

... The sustained release behavior of gliadin nanoparticles were evaluated both in phosphate buffer saline (pH ...Their mucoadhesive properties were determined by in vitro and in vivo ...

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Development and characterization of gastroretentive sustained-release formulation by combination of swelling and mucoadhesive approach: a mechanistic study

Development and characterization of gastroretentive sustained-release formulation by combination of swelling and mucoadhesive approach: a mechanistic study

... Compositions of various batches of acyclovir GR for- mulations are summarized in Table 1. Hydrophilic, mucoadhesive, polymer matrix tablets were prepared via the wet granulation method. Acyclovir, polymer(s), and ...

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Formulation design, optimization and pharmacodynamic evaluation of sustained release mucoadhesive microcapsules of venlafaxine HCl

Formulation design, optimization and pharmacodynamic evaluation of sustained release mucoadhesive microcapsules of venlafaxine HCl

... the venlafaxine loaded microcapsules was carried out in Sprague-Dawley rats by forced swim test. To carry out the study the animals were divided into four different groups (n=6), as control, naïve, pure drug treated and ...

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A NOVEL OPHTHALMIC DRUG DELIVERY SYSTEM: IN SITU GEL

A NOVEL OPHTHALMIC DRUG DELIVERY SYSTEM: IN SITU GEL

... The ophthalmic in-situ gels now days proved an palpable sustained drug delivery in various eye diseases. The formulation of in-situ gels for eye which carries the advantages like easy for administration, reduces ...

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DEVLOPMENT AND EVALUATION OF MUCOADHESIVE MICROSPHERE OF RALOXIFENE HYDOCHLORIDE

DEVLOPMENT AND EVALUATION OF MUCOADHESIVE MICROSPHERE OF RALOXIFENE HYDOCHLORIDE

... Preformulation studies were also carried out to check the compatibility between drug and various polymers using FTIR Spectrophotometer (Perkin-Elmer FTIR Spectrophotometer, USA). Spectra of samples were obtained using ...

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Design and In vitro Evaluation of a Novel Sustained Release Double Layered Tablets of Lornoxicam by using semi synthetic polymers

Design and In vitro Evaluation of a Novel Sustained Release Double Layered Tablets of Lornoxicam by using semi synthetic polymers

... fast release layer and a sustained release layer, anticipating the rapid drug release that starts in the stomach rapidly alleviate the symptoms and continuous in the intestine to maintain the ...

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MODIFIED RELEASE FORMULATIONS TO ACHIEVE THE QUALITY TARGET PRODUCT PROFILE (QTPP)

MODIFIED RELEASE FORMULATIONS TO ACHIEVE THE QUALITY TARGET PRODUCT PROFILE (QTPP)

... Extended Release Dosage Forms: Extended release products are formulated to make the drug available over an extended period after ...controlled release or targeted release is provided by the ...

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Formulation and evaluation of metformin hydrochloride extended release tablets

Formulation and evaluation of metformin hydrochloride extended release tablets

... with sustained action. To meet the above criteria Controlled release tablets of Metformin HCl were formulated with hydrophilic swellable rate controlling polymers such as Sodium alginate and HPMC as key ...

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FORMULATION AND EVALUATION OF ATOMOXETINE HCL MUCOADHESIVE MICROSPHERES

FORMULATION AND EVALUATION OF ATOMOXETINE HCL MUCOADHESIVE MICROSPHERES

... drug release characteristics of the various spheres are due to the differences in the porosity of the coat formed and its solubility in the dissolution ...drug release, good entrapment efficiency (87%) and ...

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Development and evaluation of metronidazole loaded carbopol 934P mucoadhesive microcapsules for sustained drug release at the gastric mucosa

Development and evaluation of metronidazole loaded carbopol 934P mucoadhesive microcapsules for sustained drug release at the gastric mucosa

... metronidazole mucoadhesive microcapsules varied from ...metronidazole mucoadhesive microcapsules were observed that mucoadhesion was higher when polymer concentration was achieved higher levels due to ...

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FORMULATION AND EVALUATION OF NOVEL GASTRORETENTIVE MUCOADHESIVE MICROSPHERES OF CYPROHEPTADINE HYDROCHLORIDE FOR SUSTAINED RELEASE

FORMULATION AND EVALUATION OF NOVEL GASTRORETENTIVE MUCOADHESIVE MICROSPHERES OF CYPROHEPTADINE HYDROCHLORIDE FOR SUSTAINED RELEASE

... gastroretentive mucoadhesive microspheres of Cyproheptadine hydrochloride using mucoadhesive ...in sustained release of the drug thereby providing this formulation as a potential candidate for ...

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