Multiple-Drug Resistance (MDR)
Prevalence and Multiple Drug Resistance of Shigella sonnei Isolated from Diarrheal Stool of Children
... The resistance to antibiotics is inevitable, which is a kind of defensive reaction of infectious agents, and it has been since the discovery of antibiotics ...antibiotic resistance is increasing, but the ...
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Multiple drug resistance and biocide resistance in Escherichia coli environmental isolates from hospital and household settings
... exhibited resistance to Trimethoprim-sulfamethoxazole (Fig. 1). Resistance to amoxicillin was seen in ...the resistance was seen in only 19% of the isolates. Resistance to cephalosporins ...
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Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates
... Multiple drug resistance is a condition enabling a disease causing organism to resist distinct drugs or chemicals of a wide variety of structure and function targeted at eradicating the ...multidrug ...
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Troglitazone reverses the multiple drug resistance phenotype in cancer cells
... drug resistance. We previously demonstrated doxorubicin (DOX) resistance in K562 human leukemia cells that was associated with upregulation of glyoxalase 1 (GLO-1) and histone H3 ...the ...
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Multiple Drug Resistance: A Fast-Growing Threat
... antibiotic resistance can be solved. Resistance mechanisms are pandemic and has created enormous clinical and financial burden on health care systems ...judgment. Multiple drug ...
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Mutations in the yeast PDR3, PDR4, PDR7 and PDR9 pleiotropic (multiple) drug resistance loci affect the transcript level of an ATP binding cassette transporter encoding gene, PDR5.
... The yeast pleiotropic (multiple drug) resistance gene PDR5 encodes a product with homology to a large number of membrane transport proteins including the mammalian multiple [r] ...
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Significance of MDR1 and multiple drug resistance in refractory human epileptic brain
... defined multiple drug resistance involve drug- efflux transporters such as the ATP-binding cassette sub- family B member 1 (ABCB1), also known as MDR1 or P- glycoprotein (P-gp) ...with ...
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NANOMEDICINE: will it offer possibilities to overcome multiple drug resistance in cancer?
... ideal drug deliv- ery system for a MDR treatment may well include both a biological drug cargo and a more standard small mol- ecule, packed in a nanoparticle system with a variation in size (as well as ...
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High Prevalence of Multiple Drug Resistance among ESBLs-Producing Klebsiella pneumoniae Isolated from Hospitalized Patients in Isfahan, Iran
... Production of ESBLs along or with multi drug resistance in bacteria is a serious threat and endangers patient’s survival. There are a number of studies done on determination of antibiotic resistance ...
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Overcoming multiple drug resistance mechanisms in medulloblastoma
... lines (MED1) was below the maximum tolerated dose of TMZ used in clinical trial [79]. Two novel imidazote- trazine analogues N-3 sulfoxide and N-3 propargyl TMZ derivatives used in this project were developed by ...
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Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat?
... ated resistance mutations in nematode communities of cattle, sheep, bison and horses provides a powerful new tool that enables unparalleled sensitivity of detection and permits screening for the emergence of ...
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Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces.
... While transformants containing the high copy number autonomously replicating plasmid were resistant to both cycloheximide and sulfometuron methyl, inte- grative transforma[r] ...
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Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms
... example, drug may be prevented from entering the cells or be pumped out of the cells; it may become enzymatically inactive, mutation or alteration in expression of the drug target, and derangement in ...
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ANTIMICROBIAL ACTIVITY OF STEM BARK OF COMBRETUM ALBIDUM G DON; A TRADITIONAL MEDICINAL LIANA
... of multiple drug resistance to human pathogenic organisms, this has necessitated a search for new antimicrobial substances from other sources including ...
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Role of micro-RNAs in drug resistance of multiple myeloma
... in drug resistance of MM ...melphalan resistance even in the presence of BMSCs ...modulated drug influx-efflux transporters SLC7A5/LAT1 and the ABC transporter ABCC1/MRP1, further supporting ...
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Incidence of multidrug resistant Vibrio parahaemolyticus isolated from Ponnani, South India.
... antibiotic resistance index are comparable with those observed for Vibrios from coastal and brackish water areas of Kerala ...with drug resistant groups of ...the drug resistance of ...the ...
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Identification and characterization of class 1 integrons among atypical enteropathogenic Escherichia coli isolated from children under 5 years of age.
... of multiple drug resistance of EPEC strains in this study demonstrated the presence of integrons carrying antimicrobial resistance gene ...of drug resistant ...antibiotic ...
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Diffusely Adherent E. coli Burden in Low Socio-Economic Pediatric Population
... beta-lactam resistance, leading to the high mortality rate in hospitals ...Similar resistance pattern was also reported earlier in ...ESBL resistance among human diarrheagenic ...antibiotic ...
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Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?
... BTK may promote B-cell migration via activation of the CXCR4-CXCL12 (SDF-1) axis [67]. CXCL12 is a pleiotropic chemo-attractant for CXCR4-expressing cells, including HSCs and MMSCs, and retains these cells in the BM. ...
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MULTI DRUG RESISTANT PATTERNS OF BIOFILM FORMING AEROMONAS HYDROPHILA FROM URINE SAMPLES
... of multiple individual resistance mechanisms, each of which can be either plasmid- or chromosome- ...contains multiple resistance genes on a single molecule of ...called resistance ...
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