multiple reaction monitoring
Critical Evaluation of Product Ion Selection and Spectral Correlation Analysis for Biomarker Screening Using Targeted Peptide Multiple Reaction Monitoring
... samples. Multiple reaction monitoring (MRM) is particu- larly well suited to this focused form of proteomic detection, since it offers the potential for high throughput quantization in a clinical ...
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Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance Mycobacterium tuberculosis peptides in human serum
... the multiple reaction monitoring (MRM) methods for the relative quantification of peptides ...selective reaction monitoring mode using electrospray ionization in nanospray positive ion ...
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Hair-based rapid analyses for multiple drugs in forensics and doping: application of dynamic multiple reaction monitoring with LC-MS/MS
... Background: Considerable efforts are being extended to develop more effective methods to detect drugs in forensic science for applications such as preventing doping in sport. The aim of this study was to develop a ...
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The application of multiple reaction monitoring and multi-analyte profiling to HDL proteins
... sizes. Multiple Reaction Monitoring (MRM), on the other hand, is a tandem MS (MS/MS) scan mode unique to triple quadrupole MS instrumentation that is capable of rapid, sensitive, and specific ...
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Quantitative Identification of Muscle Tissue by Means of Biomarker Peptides by Using Method of Multiple Reaction Monitoring
... This analysis used three stable peptides for the quantitative determination of two putative muscle biomarkers for pork and beef in minced meat with a 25-min analysis.. Good sensitivity [r] ...
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Using lipidomics to reveal details of lipid accumulation in developing seeds from oilseed rape (Brassica napus L.)
... by multiple reaction monitoring (MRM) using a triple quadrupole instrument after separation of the lipid classes by reverse phase HPLC as described in Materials and ...
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Histone post-translational modifications in frontal cortex from human donors with Alzheimer’s disease
... A multiple reaction monitoring mass spectrometry assay was used to measure changes in abundance of several histone PTMs in frontal cortex from human donors affected with AD (n = 6) and age-matched, ...
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Rapid metabolic profiling of Nicotiana tabacum defence responses against Phytophthora nicotianae using direct infrared laser desorption ionization mass spectrometry and principal component analysis
... (Multiple reaction monitoring); MS: (Mass spec- trometry); MS/MS: (Tandem mass spectrometry); N 2 : (Molecular nitrogen); NO: (Nitric oxide); OPO: (Optical parametric oscillator); OPP: (Oxidative ...
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Urine proteome of autosomal dominant polycystic kidney disease patients
... (Multiple Reaction Monitoring - MRM), we have carried out the analysis of individual ADPKD and control samples for a subset of proteins from ...
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Title: ANTIEPILEPTIC DRUGS: TREATMENT IN ELDERLY PATIENTS. Author: Callegari C. *, Bianchi L., Vender S Keyword: Antiepileptic drugs, elderly patients, gabapentinPage No: 96-102Abstract: Introduction: This study aims to examine qualitatively the use of AEDs in a population of elderly patients in nursing homes, including the prescription of specialist and monitoring. Methods: This p revalence study was carried out in a state-founded nursing home providing assistance and rehabilitation for elderly people. The first objective of the study is to determine the prevalence of the use of antiepileptic drugs. The second objective is to study the monitoring the dosage modification from the time of admission of the patient until the end of the study. Results: In the period of time that we took into consideration 65 of 402 patient’s monitored patients had at least one anti-epileptic therapy (prevalence of 32%). The antiepileptic drug most prescribed was gabapentin with a frequency of 63.6%. Discussion: The prevalence use of AEDs has beeen 32%. The second objective concerns the drugs monitoring and it has also been achieved and shows how gabapentin is the most prescribed drug (53.8% psychiatrist) and was introduced mainly for anxiety disorders, psychosis, neuropathic pain and mood disorders. Keywords: Antiepileptic drugs, elderly patients, gabapentin Download PDF
... The studies related to admission in all hospitals due to ADR in UK shows that ADR related admissions were 0.5% of total admission, while a study in two hospitals with medical and surgical departments the ADR related ...
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The MRZ reaction in primary progressive multiple sclerosis
... Multiple sclerosis (MS) is a chronic inflammatory auto- immune central nervous system (CNS) disorder dis- playing a variable disease course. At clinical onset, more than 85% of MS patients are classified as having ...
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Potential energy surfaces with multiple reaction paths for reaction dynamics calculations of polyatomic molecules
... In Chapter 4 a method is developed to improve a path potential, determined at low level of ab initio theory, by scaling the potential coefficients to be in agreement with an energy profi[r] ...
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Human Health Monitoring System At Home Based on Cortex-m3
... takes multiple signals and generates a large amount of data, these data can be stored in SD card and the time the system needs to work, at the sampling rate of EMG, ECG and EEG are set at 512Hz, the sampling rate ...
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R.Venkatesan*, S.Ravisankar, M.Lakshminarasu, S.D.Rajendran
... drug reaction monitoring systems had their birth after the land mark event of thalidomide ...intensive monitoring approach based on active surveillance of records might be helpful in better detection ...
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Development of protein biomarkers in cerebrospinal fluid for secondary progressive multiple sclerosis using selected reaction monitoring mass spectrometry (SRM-MS)
... selected reaction monitor- ing (SRM) mass spectrometry, have recently drawn in- tense interest to protein biomarker verification/ validation for advantages of enhanced sensitivity and specificity, ease of high ...
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Estimating nutrient concentrations from catchment characteristics across the UK
... may be in part because of the likelihood that most of the agricultural phosphate contribution is in particulate form. Orthophosphate was chosen for this study because there were more data available for this form of ...
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Adsorption of Copper in Soil and its Dependence on Physical and Chemical Properties
... soil reaction and the total supply of Fe, Al, Mn, Ca, Mg, K, P and ...of multiple correlations (i. e. collective influence of multiple soil properties) had the strongest influence combination of ...
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Monitoring the biodiversity of regions : key principles and possible pitfalls
... Five criteria for effective monitoring programmes To estimate biodiversity across broad spatial extents, monitoring programmes are needed that allow temporal trends of multiple species t[r] ...
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Monitoring the wild black bear's reaction to human and environmental stressors
... Previous findings about the seasonal adaptations of ursid hearts were based upon data obtained at a limited number of discrete time intervals from animals that were either chemically anesthetized or hand-reared and ...
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<p>A Unique Case Of Tenofovir-Induced DRESS Syndrome Associated With Raynaud’s Of The Tongue</p>
... In 1936, drug-induced hypersensitivity syndrome was fi rst described in patients who were being treated with anticonvulsants. 6 This was eventually further differen- tiated by Bouqet et al, who introduced the term DRESS ...
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