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Natural killer T

Natural killer T cells in adipose tissue prevent insulin resistance

Natural killer T cells in adipose tissue prevent insulin resistance

... invariant natural killer T (iNKT) cells have been proposed as mediators between lipid overload and insulin resistance, but recent studies found decreased iNKT cell numbers and marginal effects of ...

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The Role of Natural Killer T Cells in Cancer-A Phenotypical and Functional Approach

The Role of Natural Killer T Cells in Cancer-A Phenotypical and Functional Approach

... NKT, natural killer T; TCR, T cell receptor; NKR, natural killer receptor; MIC, major histocompatibility complex I-like molecules; ULBP, unique long-binding protein; MLL5, ...

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Advances in multiple omics of natural-killer/T cell lymphoma

Advances in multiple omics of natural-killer/T cell lymphoma

... Natural-killer/T cell lymphoma (NKTCL) is a highly ag- gressive subtype of non-Hodgkin’s lymphoma with ma- lignant proliferation of CD56+/cytoCD3+ lymphocytes [1, 2]. Epstein-Barr virus (EBV) is ...

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Natural killer T cells contribute to the control of acute retroviral infection

Natural killer T cells contribute to the control of acute retroviral infection

... Natural killer T cells (NKT cells) are innate-like T lym- phocytes, which recognize glycolipid antigens presented by the non-classical major histocompatibility complex (MHC) class I-like ...

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Extranodal Natural Killer/T-cell Lymphoma in a Child with a Prior History of Nasal Trauma: a Case Report

Extranodal Natural Killer/T-cell Lymphoma in a Child with a Prior History of Nasal Trauma: a Case Report

... Extranodal natural killer/T-cell lymphoma (ENK/TCL) is a rare subtype of NHL with a poor prognosis that has some association with Epstein- Barr virus (EBV) (1, ...

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Natural killer cells and natural killer T cells in Lyme arthritis

Natural killer cells and natural killer T cells in Lyme arthritis

... Natural killer T (NKT) cells, a subgroup of T cells comprising about 0.2% of lymphocytes, express surface antigens associated with both adaptive (T cell receptor) and innate (NK ...

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First case of primary intraocular natural killer t-cell lymphoma

First case of primary intraocular natural killer t-cell lymphoma

... Natural killer-T (NK-T) cell lymphoma, previously cate- gorized as a lethal granuloma, is now a definitive diag- nostic entity in the World Health Organization lymphoma classification ...

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Activation of human invariant natural killer T cells with a thioglycoside analogue of ? galactosylceramide

Activation of human invariant natural killer T cells with a thioglycoside analogue of ? galactosylceramide

... Invariant natural killer T (iNKT) cells are unconventional regulatory and effector T cells that recognize glycolipid antigens presented by the major histocompatibility complex (MHC) class ...

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Invariant natural killer T cells are functionally impaired in patients with systemic sclerosis

Invariant natural killer T cells are functionally impaired in patients with systemic sclerosis

... regulatory T cells; CD: Cluster of differentiation; CI: Confidence interval; CRP: C-reactive protein; dcSSc: Diffuse cutaneous SSc; DN: Double negative; ELISA: Enzyme-linked immunosorbent assay; ESR: Erythrocyte ...

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Activation and regulation of B cell responses by invariant natural killer T cells

Activation and regulation of B cell responses by invariant natural killer T cells

... Invariant natural killer T cells, also known as type 1 NKT cells, are clonally expanded T cells expressing a TCR composed of an invariant α-chain (Vα24-Jα18 in human and Vα14-Jα18 in mice) ...

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Exogenous Activation of Invariant Natural Killer T Cells by α Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza

Exogenous Activation of Invariant Natural Killer T Cells by α Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza

... Exogenous Activation of Invariant Natural Killer T Cells by α Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza Exogenous Activation of Invariant Natural Killer T Cells[.] ...

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Autologous Natural Killer Cell/Natural Killer T Cell Immunotherapy of Malignant Diseases

Autologous Natural Killer Cell/Natural Killer T Cell Immunotherapy of Malignant Diseases

... Recently, a method for the clinical-scale expansion and activation of natural killer cells and natural killer T cells for adoptive immunotherapy purposes has been reported. [130] Recent ...

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MicroRNA-155 is a potential molecular marker of natural killer/T-cell lymphoma

MicroRNA-155 is a potential molecular marker of natural killer/T-cell lymphoma

... Natural killer/T-cell lymphoma (NKTCL) is characterized by its highly aggressive nature and rapid progression. MicroRNAs (miRNAs) play key roles in the development of NKTCL. We utilized ...

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Persistent Changes in Circulating and Intestinal gamma delta T Cell Subsets, Invariant Natural Killer T Cells and Mucosal Associated Invariant T Cells in Children and Adults with Coeliac Disease

Persistent Changes in Circulating and Intestinal gamma delta T Cell Subsets, Invariant Natural Killer T Cells and Mucosal Associated Invariant T Cells in Children and Adults with Coeliac Disease

... non-γδ T cells (data not shown), in agreement with Kerttula et ...non-γδ T cells, and Vδ1 T cells in terms of frequency (A) and mean fluorescence intensity ...

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Analysis of Invariant Natural Killer T Cells in Intra-Abdominal Sepsis

Analysis of Invariant Natural Killer T Cells in Intra-Abdominal Sepsis

... modulation is that of anergy. A significant proportion of septic patients die from additional nosocomial infections post-admission, and immunosuppression secondary to T cell anergy has been proposed as a primary ...

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Transcriptional analysis of natural killer T cell development

Transcriptional analysis of natural killer T cell development

... in T-bet are selectively blocked at a relatively late stage of development, between Stage 2 (CD44 high ...Thymic T-bet -/- type I NKT cells do not express ...lacking T-bet fail to proliferate in ...

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Dynamic changes of cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, and natural killer T (NKT) cells in patients with acute hepatitis B infection

Dynamic changes of cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, and natural killer T (NKT) cells in patients with acute hepatitis B infection

... The relationship between dynamic changes in HBcAg- specific CTLs frequency, liver injury, and viral clearance HBcAg-specific CTLs levels among the 18 HLA-A0201- positive AHB patients were tested every week following ...

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Scavenger receptors target glycolipids for natural killer T cell activation

Scavenger receptors target glycolipids for natural killer T cell activation

... Scavenger receptors (SRs) comprise a large family of structur- ally diverse molecules that function as PRRs for both modified self and pathogenic non-self molecules (19). While first members of this family, such as SRA ...

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Pathogenesis and biomarkers of natural killer T cell lymphoma (NKTL)

Pathogenesis and biomarkers of natural killer T cell lymphoma (NKTL)

... Infection by EBV induces expression of genes encoding nuclear antigens, membrane proteins and non-coding RNAs in B cells, all of which induce cell proliferation and transformation into lymphoblastoid cell lines. However, ...

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Anti cancer activity of Angelica gigas by increasing immune response and stimulating natural killer and natural killer T cells

Anti cancer activity of Angelica gigas by increasing immune response and stimulating natural killer and natural killer T cells

... Fig. 7 Anti-tumor effects by ISAg were associated with boosted cytotoxicity of NK receptor-expressing innate immune cells. Yet40 B6 mice were treated via the oral route with ISAg (4 mg/injection) or PBS three times per ...

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