Natural killer T cell
First case of primary intraocular natural killer t-cell lymphoma
... NK-T: Natural killer T cell; OD: Oculus Dexter; OS: Ocular Sinister; UMIN: University Hospital Medical Information Network; CTR: Clinical Trial Registry; PCR: Polymerase chain reaction; ...
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Advances in multiple omics of natural-killer/T cell lymphoma
... Natural-killer/T cell lymphoma (NKTCL) represents the most common subtype of extranodal lymphoma with aggressive clinical behavior. Prevalent in Asians and South Americans, the pathogenesis of ...
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Extranodal Natural Killer/T-cell lymphoma, nasal type: ‘midline lethal granuloma.’ A case report
... Extranodal natural killer/T cell (NK/T cell) lymphoma, nasal type, is a rare non-Hodgkin lymphoma originating in the nasal cavity or in the paranasal ...from natural ...
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Extranodal Natural Killer/T-cell Lymphoma in a Child with a Prior History of Nasal Trauma: a Case Report
... Extranodal natural killer/T-cell lymphoma (ENK/TCL) is a rare aggressive cancer that presents with a midline facial lesion that could easily be misdiagnose (1, ...
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MicroRNA-155 is a potential molecular marker of natural killer/T-cell lymphoma
... Natural killer/T-cell lymphoma (NKTCL) is characterized by its highly aggressive nature and rapid ...NKTCL cell lines with expression in normal NK ...
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CD30 expression in extranodal natural killer/T-cell lymphoma, nasal type among 622 cases of mature T-cell and natural killer-cell lymphoma at a single institution in South China
... including cell cycle arrest, apoptosis, and acti- vation of the pro-survival transcription factor nuclear factor kappa-light-chain-enhancer of activated B cells ...in T cells and NK cells ...mature ...
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Autologous Natural Killer Cell/Natural Killer T Cell Immunotherapy of Malignant Diseases
... NK/NKT cell number and antitumor function continuing to decline as disease progresses ...NK cell and/or NKT cell activity and tumor infiltration rates have been established as independent prognostic ...
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α Galactosyl Phytosphingosine 2,6’ Diamide as an Inducer of Invariant Natural Killer T Cell
... NKT cell frequencies were determined by flow cytometry. NKT cell frequencies were defined as the percentage of V 24 + /V 11 + NKT cells among gated lymphocytes in the upper right (UR) corner (Q2) for ...
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Scavenger receptors target glycolipids for natural killer T cell activation
... NKT cell agonist PBS-57 (38) was evolved from αGalCer by the combina- tion of 2 modifications: the addition of an acetamide group at the C6′′ position of the galactose (PBS-14) and the introduction of a single ...
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Glycolipid antigen induces long term natural killer T cell anergy in mice
... NKT cell anergy is predominantly NKT cell autonomous and suggest that chronic stimulation with α-Gal- Cer is not required for maintenance of the anergic ...
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Transcriptional analysis of natural killer T cell development
... the product of gene duplication, they share 95% sequence homology with each other (Zajonc, 2016; Dascher and Brenner, 2003). Mouse CD1d molecules are primarily expressed by cells of the hematopoietic lineage, including B ...
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Pathogenesis and biomarkers of natural killer T cell lymphoma (NKTL)
... Enhancer of zeste homologue 2 (EZH2) is a H3K27-specific histone methyltransferase and a catalytic subunit of the polycomb repressive complex 2 (PRC2) molecule. EZH2 is aberrantly expressed in NKTL, at both the protein ...
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Aggressive mature natural killer cell neoplasms: from epidemiology todiagnosis
... Natural killer/T cell lymphoma, nasal type, are histologi- cally characterized by angiocentricity and invasion of the blood vessels by lymphoma cells, resulting in ischemic necrosis; the ...
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Persistent Changes in Circulating and Intestinal gamma delta T Cell Subsets, Invariant Natural Killer T Cells and Mucosal Associated Invariant T Cells in Children and Adults with Coeliac Disease
... γδ T cell subsets is not surprising given the broad expression of this molecule in the intestine - on dendritic cells, macrophages, B cells and intestinal epithelial cells ...γδ T cell in ...
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Mouse Cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells
... NK cell number after 40 h ...NK cell frequency and number were detectable between the two groups (Figure ...NK cell boosting effect of Treg depletion is completely abolished upon MCMV ...NK ...
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Dynamic changes of cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, and natural killer T (NKT) cells in patients with acute hepatitis B infection
... cells were removed and 200 μl deionized water was added and incubated on ice for 10 min. After washing ten times with PBS containing 0.05% Tween-20, 100 μl biotinylated anti-IFN-g antibody was added to each well and ...
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Aggressive natural killer cell leukemia or extranodal NK/T cell lymphoma? a case with nasal involvement
... NK cell neoplasm with an aggressive clinical course and poor ...NK cell neoplasm is ENKTL, which is has a higher incidence than ANKL ...NK/T cell lymphoma can be further classified into the ...
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Improved Natural Killer cell activity and retained anti tumor CD8+ T cell responses contribute to the induction of a pathological complete response in HER2 positive breast cancer patients undergoing neoadjuvant chemotherapy
... α -CD56 PE monoclonal antibodies. Briefly, after CD56 staining in 10% rabbit serum, cells were fixed and per- meabilized as described above at 4°C, washed twice, and labeled with NF- κ B antibody (1:100) in PBS 2% rabbit ...
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Transplantation and innate immunity: the lesson of natural killer cells
... the natural immune system, which each single individual possesses, and are of funda- mental importance to limit or eradicate pathogens during the early phases of a primary infection, ...before T and B cells ...
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Potential role of natural killer cells in controlling tumorigenesis by human T-cell leukemia viruses.
... NK cell protection, mice were coinoculated with RV- ATL and SLB-I ...NK cell- mediated ...NK cell cytolytic activity could occur by direct cell-to-cell interactions, as described for ...
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