neurodegenerative disorders
Loss of Lag Response Curvilinearity of Gait Poincare Plot Indices in Neurodegenerative Disorders
... It is reported in the literature that the temporal structure of gait variability in healthy subjects ex- hibits deterministic processes where not only each stride is correlated with the neighbouring strides (i.e. ...
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Current advances in using neurotrophic factors to treat neurodegenerative disorders
... various neurodegenerative disorders is worth serious consideration, given the fact that so many attempts with monotherapies have not yielded any ...non-neurodegenerative disorders co-therapies ...
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The Role of Glutamate Dehydrogenase Activity in Development of Neurodegenerative Disorders
... neurological disorders and degeneration of mul- tiple neuronal ...with neurodegenerative disorders may be one of the reasons for the neuro-excito- toxic glutamate ...
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Recent progress in translational research on neurovascular and neurodegenerative disorders
... neurovascular disorders and a multitude of novel and well validated findings sustain the hope that our therapeutic options arse- nal may be both augmented and improved in the mid-term ...chronic ...
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The role of iron in neurodegenerative disorders : insights and opportunities with synchrotron light
... X-ray fluorescence was used to analyze iron in neurodegenerative disorders as early as 1968, using a laboratory X-ray source (Earle, 1968). XRF spectra showing elemental intensity as a function of angle, ...
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Stem cells in human neurodegenerative disorders — time for clinical translation?
... of neurodegenerative diseases can improve function by replacing the lost neurons and glial cells and by mediating remyelination, trophic actions, and modulation of ...
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The role of gene variants in the pathogenesis of neurodegenerative disorders as revealed by next generation sequencing studies: a review
... complex disorders Many neurodegenerative disorders that are common and predominantly sporadic also have familial ...Mendelian disorders, it is also invalu- able in uncovering genetic causes in ...
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NADPH oxidase in brain injury and neurodegenerative disorders
... neurodegenerative disorders, preclinical studies have been limited due to many ...these disorders [73], as this approach may offer the best therapeutic option for treating disorders associated ...
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Classification of Neurodegenerative Disorders Based on Major Risk Factors Employing Machine Learning Techniques
... In longitudinal analyses of 746 subjects we found that there was a strong association between the risk of neurodegenerative disorders such as AD, VD and PD. The classification model was developed employing ...
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Of scents and brain: Olfactory stimulation for Neuropoeisis and intervention for Neurodegenerative Disorders
... treating neurodegenerative disorders like dementia, Alzheimer’s and Parkinson’s as well as psychiatric symptoms like mood disturbances, anxiety and sleep ...
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The Role of Alpha- Synuclein And Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders
... of neurodegenerative disorders has generally been attributed to accumulation of proteins like α-syn and impairment of cellular functions such as mitochondrial, and lysosomal or proteasomal dysfunction ...
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Lysosomal dysfunction in proteinopathic neurodegenerative disorders: possible therapeutic roles of cAMP and zinc
... generative disorders that includes Alzheimer’ s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis ...these neurodegenerative diseases, aging itself is accompanied by lysosomal dys- ...
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Comparative quantitative study of ‘signature’ pathological lesions in the hippocampus and adjacent gyri of 12 neurodegenerative disorders
... neurodegenerative disorders. To compare HC pathology among disorders, densities of ‘signature’ pathological lesions were measured at a standard location in eight brain regions of twelve ...suggested ...
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NF κB in neuronal plasticity and neurodegenerative disorders
... NF- κ B in chronic neurodegenerative disorders Alzheimer’s disease. Studies of postmortem brain tissue from patients with Alzheimer’s disease (AD) have revealed increased NF-κB activity in cells involved in ...
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Pharmacoinformatic and molecular docking studies reveal potential novel antidepressants against neurodegenerative disorders by targeting HSPB8
... Abstract: Charcot–Marie–Tooth (CMT) disease is an inherited peripheral neuromuscular disorder characterized by length-dependent and progressive degeneration of peripheral nerves, leading to muscular weakness. Research ...
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The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile
... This review will discuss some issues related to the risk/benefit profile of the use of dietary antioxidants. Thus, recent progress regarding the potential benefit of dietary antioxidants in the treatment of chronic ...
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Hydrogen sulfide, nitric oxide, and neurodegenerative disorders
... ing neurodegenerative disorders and brain aging can form blood-cerebrospinal fluid barrier and this may interfere choroid-plexus gateway activity ...
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A comparison of the spatial patterns of β-amyloid (Aβ) deposits in five neurodegenerative disorders
... the mean dimension of the clusters in a plane parallel to the pia mater. Regularly spaced clusters are indi- cated by the V/M ratio increasing to a peak before declining at larger field sizes, the location of the peak ...
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Brain-barrier Regulation, Metal (Cu,Fe) Dyshomeostasis and Neurodegenerative Disorders in Man and Animals. Susan Haywood
... Neurological disorders of cognitive and sometimes motor processes are characterised by the presence of misfolded proteins causing neuronal ...these disorders have a common endpoint usually involving metals ...
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Size frequency distributions of β-amyloid (Aβ) deposits:a comparative study of four neurodegenerative disorders
... type A β deposit [4]. Disaggregation within a deposit may also occur as a result of the removal of A β mo - nomers by glial cells which are frequently embedded within and present at the periphery of many diffuse and ...
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