Neutron capture therapy
A realistic appraisal of boron neutron capture therapy as a cancer treatment modality
... Boron neutron capture therapy (BNCT) is a binary therapeutic modality based on the nuclear capture and fission reac- tions that occur when the stable isotope boron-10 is irradiated with ...
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Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism
... boron neutron capture therapy (BNCT), p-boronophenylalanine (BPA) has been the most powerful drug owing to its ability to accumulate selectively within cancers through cancer-related amino acid ...
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Arene ruthenium dithiolato–carborane complexes for boron neutron capture therapy (BNCT)
... Boron neutron capture therapy is the traditional area for application of dicarba-closo-dodecarborane molecules in ...this therapy depends on the number of boron atoms delivered to cancer ...
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Evaluation of Boron Content Liposome Modified Protein- Transduction Domains for Boron Neutron Capture Therapy
... radiation therapy as a treatment for malignant tumors becomes greater every year, but radiation therapy-resistant tumors still exist, and are known as convalescence ...Boron neutron capture ...
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Thermal neutron Relative Biological Effectiveness factors for Boron Neutron Capture Therapy from in vitro irradiations
... thermal neutron factors is fundamental in Boron Neutron Capture ...fast neutron doses, although such an approach has been ...low-energy neutron beam has been used to determine thermal ...
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Impacts of multiple-field irradiation and boron concentration on the treatment of boron neutron capture therapy for non-small cell lung cancer
... Boron neutron capture therapy (BNCT) is a radiotherapy that combines biological targe ng and high linear energy ...Accelerator-based neutron source called “Neuboron source” was used and mul ...
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Boron neutron capture therapy – redefining radiotherapy
... radiation therapy for cancer’s that is based upon the selective uptake of non-radioactive boron ...a neutron beam causing boron ( 10 B) to be transformed into 11 B, which would disintegrate releasing an α ...
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Physicochemical investigation of the influence of saccharide-based parenteral formulation excipients on l-p-boronphenylalanine solubilisation for boron neutron capture therapy
... Boron Neutron Capture Therapy (BNCT) is a niche cancer radiotherapy treatment requiring the administration and tumour selective uptake of a boron-10 enriched compound followed by tumour irradiation ...
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Development of LINAC-Based Neutron Source for Boron Neutron Capture Therapy in University of Tsukuba
... boron neutron capture therapy (BNCT) have been conducted using research ...accelerator-based neutron source for ...the neutron target material. To generate sufficient neutron ...
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FBPA PET in boron neutron capture therapy for cancer: prediction of 10B concentration in the tumor and normal tissue in a rat xenograft model
... Boron neutron capture therapy (BNCT) is a molecular radiation treatment based on the 10 B (n, α ) 7 Li nuclear reaction in cancer cells, in which delivery of 10 B by 4-borono-phenylalanine conjugated ...
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A Monte Carlo study of SPECT in boron neutron capture therapy for a heterogeneous human phantom
... Boron neutron capture therapy (BNCT) is a binary radiotherapy combining biochemical targe ng with neutron irradia ...boron capture reac on can be used to address the ...a neutron ...
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Deterministic Parsing Model of the Compound Biological Effectiveness (CBE) Factor for Intracellular 10Boron Distribution in Boron Neutron Capture Therapy
... previously developed a deterministic parsing model to determine the Compound Biological Effec- tiveness (CBE) factor in Borono-Phenyl-Alanine (BPA)-mediated Boron Neutron Capture Therapy (BNCT). In ...
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Hemorrhage in mouse tumors induced by dodecaborate cluster lipids intended for boron neutron capture therapy
... Abstract: The potential of boron-containing lipids with three different structures, which were intended for use in boron neutron capture therapy, was investigated. All three types of boron lipids ...
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Boron delivery agents for neutron capture therapy of cancer
... The major problem with both BSH and BPA is the sig- nificant variability in tumor uptake, especially in brain tumors. This was clearly demonstrated by Goodman et al. [46]. in a biodistribution and pharmacokinetic study ...
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Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer
... Optimal therapy has not been established and prognosis is gen- erally poor (Tanvetyanon et ...Boron Neutron Capture Therapy (BNCT) has also been ...
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Boron Neutron Capture Therapy (BNCT) - Low-Energy Neutron Spectrometer for Neutron Field Characterization -
... radiation therapy is be- ing developed, i.e., boron neutron capture therapy ...strong neutron source and re- lies only on available experimental nuclear ...based neutron source ...
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^.,,.,.,.,.. XA Clinical treatment planning for subjects undergoing boron neutron capture therapy at Harvard-MIT
... Subsequent steps involve the CT and MRI scanning of the subject to generate source images for the computational synthesis of a customized anatomical model for Monte Carlo treatment plann[r] ...
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Boron neutron capture therapy for vulvar melanoma and genital extramammary Paget’s disease with curative responses
... All patients were treated according to the treatment pro- cedure developed by Mishima et al. [19, 29]. BNCT was carried out at the Kyoto University Research Reactor (KUR) operating at 5 MW of power using an epithermal ...
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<p>Remarkable Boron Delivery Of iRGD-Modified Polymeric Nanoparticles For Boron Neutron Capture Therapy</p>
... Combined-modality therapy is increasingly recom- mended in management to achieve a better outcome for ...radio- therapy than that of single modality, for that doxorubicin can enhance radiosensitivity in ...
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A History of 20th-Century Boron Neutron-Capture Therapy
... and pericapillary tissues, during neutron irradiation for clinical BNCT. Of seventeen terminally ill brain–tumor patients similarly infused intravenously with sodium pentaborate and irradiated with increasing ...
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