New Biomarkers
Potential new biomarkers for squamous carcinoma of the uterine cervix
... Aim An in silico pathway analysis was performed in an attempt to identify new biomarkers for cervical carcinoma. Methods Three publicly available Affymetrix gene expression data sets (GSE5787, GSE7803, ...
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Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia
... In recent years, the discovery of non-coding RNAs (ncRNAs) has provided new tools for the understanding of cancer biology [14]. ncRNAs are functional transcripts that do not code for proteins, but indeed play a ...
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Potential new biomarkers for endometrial cancer
... We evaluated overall patient survival in patients with the highest 20% of biomarker expression and patients with the lowest 20% biomarker expression to determine whether the elevation of these genes had any impact on ...
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NEW BIOMARKERS AS INDICATORS FOR SEPSIS IN FEBRILE LEUKAEMIC IRAQI PATIENTS
... Background: Sepsis in leukaemic patients is a leading killer of both adult and pediatric patients. Analysis of cytokine levels measured around the onset of bactaeremia indicated that IL-8 followed by IL-6 are potentially ...
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Classification of New Biomarkers of Dilated Cardiomyopathy Based on Pathogenesis—An Update
... potential biomarkers for dilated cardio- myopathy is a challenge owing to various aetiologies ...the biomarkers involved in DCM will ultimately give a better insight about which pathophysiological pathways ...
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New biomarkers for primary mitral regurgitation
... Whereas MR is a common valvular heart disease with an increased prevalence due to the population aging, lit- tle is known about its underlying physiological deregula- tion. This study aims to highlight underlying ...
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MicroRNAs: new biomarkers and therapeutic targets after cardiac arrest?
... only new bio- markers for neurological prognosis but also novel candi- dates for neuroprotective therapy targets that may be investigated following cardiac ...
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Novel Biomarkers Aim at Detecting Metastatic Sentinel Lymph Nodes in Breast Cancer
... find new biomarkers to improve diagnostic accuracy in the detection of metastatic axillary lymph nodes in breast cancer ...selected new markers, KLK11 and CLEC3A, was evaluated in pathologically ...
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Laboratory biomarkers or imaging in the diagnostics of rheumatoid arthritis?
... candidate biomarkers for seronegative RA ...several new biomarkers may help to identify at risk patients and those with early ...serological biomarkers to improve diagnosis of ...
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Paraffin Sections of Sputum Block: Description of a New Method for Pathological and Molecular Study
... identify new biomarkers of exposure or susceptibility in patients with lung pathology to enhance the understanding of airways changes due to different etiological factors and may be useful to find ...
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Overexpression of c-kit(CD117), relevant with microvessel density, is an independent survival prognostic factor for patients with HBV-related hepatocellular carcinoma
... explore new biomarkers for indicating the recurrence and prognosis in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) patients after tumor resection, we investigated the expression and ...
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On the assessment of the added value of new predictive biomarkers
... and the full model h p+q = i=1 p w i x i + j=1 q w p+j x p+j . Statistical significance tests such as the LR test and the Wald test are readily available for the commonly used logistic regression model. In these tests, ...
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IDENTIFICATION OF NEW MOLECULAR BIOMARKERS - PROTEOMICS
... revealed that human growth hormone (hGH) is of great importance in the progression of this disease. Namely, growth hormone can be one of the main drivers of the metastasis process. By coagulating the breast carcino- ma ...
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Microvesicles/exosomes as potential novel biomarkers of metabolic diseases
... for new biomarkers: (1) EMVs are identifiable and isolatable on the basis of typical intrinsic and well-defined properties, such as phosphatidylserine content, size, sedimentation behavior; (2) EMVs are ...
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Myocardial injury in diabetic patients with multivessel coronary artery disease after revascularization interventions
... An interesting study from Verdoia et al. evaluated the effect of diabetes in PMI and myonecrosis after PCI treat- ment [18]. Using the release of CK-MB and troponin to define PMI and myonecrosis, the authors found that ...
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Upregulated expression of serum exosomal miR-375 and miR-1307 enhance the diagnostic power of CA125 for ovarian cancer
... Tumor biomarker are now the focus of tumor re- search, recent studies have discovered various potentials of tumor biomarker in Gynecological Oncology in addition to the diagnostic. For example, p16 INK4a pro- tein has ...
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The current and future state of companion diagnostics
... The move to multiplex assays has significant implications for the business models of diagnostic developers. Today, many companion diagnostics are initially developed under the ASR approval pathway and conducted in ...
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Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets
... predictive biomarkers of response to these agents in RCC or other solid tumor types, and in excess of 30% of patients will not derive benefit from ...surrogate biomarkers, which will help select patients ...
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Medical imaging in personalised medicine: a white paper of the research committee of the European Society of Radiology (ESR)
... imaging biomarkers can help identify individuals suited for preventive ...imaging biomarkers to these genetic and molecular ...this new par- adigm as it will mean changes in training, clinical ...
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New developments and future opportunities in biomarkers for amyotrophic lateral sclerosis
... Other new MUNE methods, including Bayseian MUNE and motor unit num- ber index (MUNIX), the latter was considered to be a reli- able electrophysiological biomarker to track lower motor neuron loss in ALS ...
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