NF-κB transcription factor
Anti Inflammatory properties of Salograviolide A purified from Lebanese plant Centaurea ainetensis
... Interest in alternatives to modern medicine has never been higher than it is now, and a large part of this interest revolves around the use of medicinal plants. Many of the anti-inflammatory activities of some medicinal ...
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Constitutive Activation of the Transcription Factor NF-κB Results in Impaired Borna Disease Virus Replication
... active NF- B and BDV infectivity in the rat brain. Activated NF- B, defined by immunohistological stain- ing using a phospho-specific antibody directed against the p65 subunit, is regularly found in ...
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Original Article GF109203X attenuates RANKL-induced osteoclastogenesis and suppresses osteolysis in a mouse model
... of NF-κB, NFAT, and ERK phosphorylation in the process of osteoclastogenesis [29, 32, ...RANKL-induced NF-κB and NFAT transcription factor activity, GF109203X was shown to ...
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Radiation Resistance In Radiotherapy : A Review
... of NF- κB which is a transcription factor that increases tumor growth, degrades ionizing radiations as well as resist the chemotherapeutic effect during ...that NF- κB is ...
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Oncogenic Signaling Pathways in Cancer: An Overview Afshin Derakhshani 1# , Zeinab Rostami 2# , Sina Taefehshokr 3, Hossein Safarpour4 , Reza Vaezi Astamal 5, Nima Taefehshokr6 , Nazila Alizadeh 7, Antonella Argentiero8 , Nicola Silvestris 9* Behzad Baradaran 10*
... Several transcription factors, such as Slug, Snail, ZEB, and Twist play pivotal roles in enhancing EMT, which are modulated by AKT and ...control NF-κB, which is a transcription factor ...
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NF κB: pivotal mediator or innocent bystander in atherogenesis?
... of transcription factors may be critical in both the initi- ation and expansion of lesions, as well as in protecting the vessel wall from the formation of atherosclerotic ...tion factor, NF- κ B, ...
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Organ specific roles for transcription factor NF κB in reovirus induced apoptosis and disease
... of transcription factor NF-kB complexes containing p50 and p65/RelA ...of NF- kB in this process, we tested the capacity of reovirus to induce apoptosis in mice lacking a functional nfkb1/p50 ...
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Molecular mechanisms of HIV latency
... HIV transcription is reactivated so that antiretroviral therapy and the immune system clear the infection, has been proposed as one approach to curing ...viral transcription factors in such a way as to ...
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Anti inflammatory activity of the ethanol extract of Dictamnus dasycarpus leaf in lipopolysaccharide activated macrophages
... the NF-κB signaling pathway [21]. NF-κB is an important transcription factor and its activa- tion plays a vital role in the secretion of various proinflam- matory mediators such ...
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Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity
... growth factor starvation ...of transcription factor nuclear factor kappa B (NF-κB) in a subset of aged cells and plays a role in mediating inflammatory ...
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Original Article Expression of NF-κB and PCNA in gastric mucosa-associated lymphoid tissue lymphoma and its clinical significance
... nuclear transcription factor κB (NF-κB) and PCNA in gastrric mucosa-associated lymphoid tissue (MALT) lymphoma, and analyze its relationship with clinicopathological char- ...The ...
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NF κB determines localization and features of cell death in epidermis
... layers, NF-κB translocates from the cytoplasm to the nucleus and induces target gene ...tissues, NF-κB acti- vation in these cells suggests that this transcription factor ...
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A systems biology approach to explore the dynamics and interactions of the NF-κB signalling pathway
... significance of this remains unclear. In the study by Sung et al., it was further observed that there was no increase in gene expression for ten genes of interest following LMB treatment, including IκBα. The argument ...
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... the NF-κB-dependent inflammatory pathway increased TNF-α expression in OSAHS patients, and the activation of the HIF-1-dependent adaptive pathway increased the serum erythropoietin (EPO) levels in severe ...
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NF κB modulated miR 130a targets TNF α in cervical cancer cells
... Nuclear factor- κ B (NF- κ B) is a nuclear transcription fac- tor that regulates the expression of a large number of genes associated with inflammation [1,2], tissue damage and repair [3,4], cell ...
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Androgen receptor activity modulates responses to cisplatin treatment in bladder cancer
... a transcription factor that induces anti- apoptotic proteins, has been considered as a key molecule for CDDP resistance ...or NF-κB expression, and ...of NF-κB and its binding to ...
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Series Introduction: The transcription factor NF κB and human disease
... the transcription factor NF-kB has attracted widespread interest based on its unusual regulation, the variety of stimuli that activate it, the diverse genes and biological responses that it controls, ...
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Reovirus-Induced Apoptosis Requires Activation of Transcription Factor NF-κB
... that NF-B activation can be achieved by a broad spectrum of biochemical inducing cues, resulting in either enhancement (1, 29, 32) or inhibition (6, 8, 65) of programmed cell death (reviewed in reference ...of ...
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Control of oncogenesis and cancer therapy resistance by the transcription factor NF κB
... of NF-κB in oncogenesis is not ...c-Rel, NF-κB2 (p100/p52), and Bcl-3 proteins are located within regions of the genome that are involved in rearrangements or ...with NF- κ B2 was originally ...
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The transcription factor NF-κB control of oncogenesis and cancer therapy resistance.pdf
... of NF- UB, via the expression of the super-repressor IUBK, led to the induction of apoptosis when an oncogenic allele of H-Ras (RasV12) was expressed ...of NF-UB in transformed cells can induce apoptosis ...
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