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Nitric Oxide

NITRIC OXIDE: A NOVEL THERAPEUTIC TARGET

NITRIC OXIDE: A NOVEL THERAPEUTIC TARGET

... impaired nitric oxide (NO) bioavailability is well- recognized in the pathology of endothelial dysfunction or atherosclerosis, respectively, and characterized by a reduced NO biosynthesis, an accelerated ...

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NITRIC OXIDE: ROLE IN HUMAN BIOLOGY

NITRIC OXIDE: ROLE IN HUMAN BIOLOGY

... Nitric oxide (NO), a free radical, possesses various modulatory effects on biological systems. NO is synthesized from L- arginine by converting it to L-citrulline via nitric oxide synthase ...

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Effects of chitosan on nitric oxide production and inducible nitric oxide synthase activity and mRNA expression in weaned piglets

Effects of chitosan on nitric oxide production and inducible nitric oxide synthase activity and mRNA expression in weaned piglets

... NO is an important host defence effector in in- nate immunity. It is generated in various tissues from l-arginine by different forms of nitric oxide synthase: neuronal NOS, iNOS, and endothelial NOS (Nathan ...

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New nitric oxide donor drugs

New nitric oxide donor drugs

... for nitric oxide donors is the treatment of angina pectoris, the intense pain caused by the spasmic contraction of the cardial ...of nitric oxide from organic ...of nitric oxide ...

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New nitric oxide releasing materials

New nitric oxide releasing materials

... reaction of NO and water. Studies have shown, however, that nitric oxide undergoes no hydrolysis in an aqueous environment. This lack of reaction with water is essential for the use of NO in the body. It ...

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Zeolite catalysts for nitric oxide production

Zeolite catalysts for nitric oxide production

... Nitric oxide catalytic tests were performed in the same way as the acid sites, as well as further studies that considered copper leaching, toxicology of HEK 293 cells, NO production from[r] ...

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Nitric oxide system and diabetic nephropathy

Nitric oxide system and diabetic nephropathy

... Endothelial dysfunction has also been shown to lead to an uncoupling of the vascular endothelial growth factor (VEGF)-nitric oxide axis resulting in enhanced proin- flammatory and proliferative effects of ...

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Nitric oxide loading of the salivary nitric oxide carrying hemoproteins (nitrophorins) in the blood sucking bug Rhodnius prolixus

Nitric oxide loading of the salivary nitric oxide carrying hemoproteins (nitrophorins) in the blood sucking bug Rhodnius prolixus

... The blood-sucking bug Rhodnius prolixus contains a salivary nitrovasodilator (Ribeiro et al. 1990) that, in concert with other activities, helps the insect to locate blood (Ribeiro and Garcia, 1981). This vasodilator is ...

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Role of nitric oxide in the gastrointestinal tract

Role of nitric oxide in the gastrointestinal tract

... Worldwide osteoarthritis (OA) affects more than 9.6% of men and 18% of women older that 60 years. Treatment for OA often requires chronic use of selective or nonselective nonsteroidal anti- inflammatory drugs (NSAIDs), ...

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Vascular nitric oxide: formation and function

Vascular nitric oxide: formation and function

... Abstract: Nitric oxide (NO) is a structurally simple, highly versatile molecule that was originally discovered over 30 years ago as an endothelium-derived relaxing ...

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Nitric Oxide. Springer. B. Mayer

Nitric Oxide. Springer. B. Mayer

... E. Nitric Oxide Synthase Isoforms in the Kidney 329 C. Distribution of NOS in the Kidney 330 I.Distribution of NOS in the Renal Vasculature 330 II. Distribution of NOS in Renal Tubules 3[r] ...

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C-786T (Promoter) Allelic Variants of Nitric Oxide Synthase Gene and Its Association with Nitric Oxide in Preeclampsia

C-786T (Promoter) Allelic Variants of Nitric Oxide Synthase Gene and Its Association with Nitric Oxide in Preeclampsia

... of nitric oxide 3 gene polymorphisms and preeclampsia-risk states that it is a clinical syndrome characterized by new-onset of hypertension and proteinuria after 20 weeks of gestation 1 ...

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The biosynthesis of nitric oxide from L-arginine. Nitric oxide formation features and its functional role in mitochondria

The biosynthesis of nitric oxide from L-arginine. Nitric oxide formation features and its functional role in mitochondria

... dothelium, nitric oxide diffuses to smooth muscle syncytia, activating sGC in myocytes and nitrosyla- ting target ...with nitric oxide activates the mentioned ...

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Serum Nitric Oxide Level and Endothelial Nitric
Oxide Synthase Gene INTRON4 VNTR Polymorphism in
Essential Hypertension.

Serum Nitric Oxide Level and Endothelial Nitric Oxide Synthase Gene INTRON4 VNTR Polymorphism in Essential Hypertension.

... . Nitric oxide, the one considered to be the main factor involved in endothelial dysfunction, is found to be the main mediator involved in shear ...endothelial nitric oxide synthase gene in ...

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Effect of anticonvulsants on the nitric oxide system

Effect of anticonvulsants on the nitric oxide system

... The effect of phenobarbital, carbamazepine, valproate sodium, depakine, topiramate and lamo- trigine on the content of NO and NO-synthase ac- tivity in white rat brain tissues has been studied. It was established that ...

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Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta stimulated rat mesangial cells

Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta stimulated rat mesangial cells

... Nitric oxide (NO) plays an important role in immunological reactions as a host defense mechanism against tumor cells and invasive microorganisms, but it may also damage healthy ...

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Is Nitric Oxide a Hormone?

Is Nitric Oxide a Hormone?

... Nitric oxide (NO) is a simple ubiquitous signaling molecule and plays important roles in almost every biological system. Recent evidences suggest that NO may act as an endocrine molecule. The aim of this ...

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Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides

Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides

... In this study, we have identified the source of nitric oxide (NO) produced in the human inflammatory joints by analyzing expression of inducible NO synthase. In ex vivo organ cultures, both inflammatory ...

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Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis

Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis

... Nitric oxide (NO) is an important mediator in both health and disease. In addition to its effects on vascular tone and platelet function, it plays roles in inflammation and pain perception that may be of ...

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Hypergravity upregulates renal inducible nitric oxide synthase expression and nitric oxide production

Hypergravity upregulates renal inducible nitric oxide synthase expression and nitric oxide production

... inducible nitric oxide synthase (iNOS) pathway is one of the signaling pathways that are activated during these ...of nitric oxide (NO) and is normally undetectable under physiological ...

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