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Non-viral drug delivery

Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers

Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers

... of viral nu- cleotide delivery with varying degrees of ...proteins, viral particles and siRNA under endosomal acid- ification ...either drug delivery or for diagnostic purposes (imaging ...

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REVIEW ON NON VIRAL DELIVERY SYSTEMS FOR siRNA

REVIEW ON NON VIRAL DELIVERY SYSTEMS FOR siRNA

... siRNA delivery systems/ vehicles that can achieve targeted delivery and replicate the invitro ...siRNA delivery system selection is based on target cell ...siRNA delivery systems are ...

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NON DESTRUCTIVE METHOD FOR GENE AND DRUG DELIVERY IN LIVING CELL

NON DESTRUCTIVE METHOD FOR GENE AND DRUG DELIVERY IN LIVING CELL

... 6. Viral vectors; ...safe, non toxic and non viral ...transdermal delivery has opened up a new possibility to introduce larger molecules such as peptide hormones and vaccines as well as ...

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Targeted, systemic non viral delivery of small interfering RNA in vivo

Targeted, systemic non viral delivery of small interfering RNA in vivo

... of drug targets in mammalian ...a non-specific interferon pathway (through interaction with the protein kinase PKR 1 and 2’,5’-oligoadenylate synthetase 2 ) rather than ...

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Discrete-choice modelling of patient preferences for modes of drug administration

Discrete-choice modelling of patient preferences for modes of drug administration

... of drug administration when com- pared with intravenous or subcutaneous routes condi- tional on the other ...of drug ad- ...of drug delivery when compared with needle- free routes, perhaps ...

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DEVELOPMENT AND EVALUATION OF FLUOCINOLONE ACETONIDE AND NEOMYCIN SULPHATE NANOMIEMGEL FOR TOPICAL DRUG DELIVERY SYSTEM

DEVELOPMENT AND EVALUATION OF FLUOCINOLONE ACETONIDE AND NEOMYCIN SULPHATE NANOMIEMGEL FOR TOPICAL DRUG DELIVERY SYSTEM

... In-vitro diffusion was performed by modified Franz diffusion cell. A glass cylinder having both ends open, 3.7 cm outer diameter, 3.1 cm inner diameter and 10 cm height was used as diffusion cell. A cellophane membrane ...

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FLOATING DRUG DELIVERY SYSTEM: A REVIEW

FLOATING DRUG DELIVERY SYSTEM: A REVIEW

... of drug delivery. Effective oral drug delivery may depend upon the factors such as gastric emptying process, gastrointestinal transit time of dosage form, drug release from the dosage ...

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 NANO-STRUCTURES FOR NON-VIRAL GENE DELIVERY FOR CANCER THERAPY: A REVIEW

 NANO-STRUCTURES FOR NON-VIRAL GENE DELIVERY FOR CANCER THERAPY: A REVIEW

... as delivery vehicles for biologically active, other possible biomedical applications include vaccination and gene ...gene delivery vehicles, it is essential to characterize their interactions with ...or ...

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Protein and peptide drug delivery system

Protein and peptide drug delivery system

... polymeric drug delivery system preparation by the mixing of monomer with the drug an initiator and a cross linking ...intravascular delivery of the protein via hydro system that is photo ...

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Lessons to be learnt from Leishmania studies

Lessons to be learnt from Leishmania studies

... of drug resistance and relapse in endemic regions such as India and Nepal ...that drug resistance is being introduced into the parasite population, possibly due to incorrect dosing by individuals ...for ...

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Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers

Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers

... gene delivery which showed higher transfection efficiency than G2 and G5 PAMAM dendrimers and comparable efficiency with bPEI 25 kDa ...DNA delivery [201-203, ...gene delivery car- riers is to ...

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NOVEL DRUG DELIVERY SYSTEM THROUGH NASAL (NON INVASIVE)

NOVEL DRUG DELIVERY SYSTEM THROUGH NASAL (NON INVASIVE)

... and non-movable microvillus which is highly responsible for increasing surface area due to non-movable ...The drug absorption is ...a drug that binds with mucociliary area as they could be ...

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Constitutive and inducible co-expression systems for non-viral osteoinductive gene therapy

Constitutive and inducible co-expression systems for non-viral osteoinductive gene therapy

... For tissue regenerative gene therapy approaches, the inherent drawback of loss of transgene expression in transient gene therapy is actually a desired safety feature. Temporally regulated, or restricted expression, of ...

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Recent advances in the development of gene delivery systems

Recent advances in the development of gene delivery systems

... gene delivery system ...gene delivery in vivo to the liver has been developed ...gene delivery systems have been reported ...gene delivery in mouse lung endo- thelial cells ...for ...

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NOVEL DRUG DELIVERY SYSTEM IN HERBAL’S

NOVEL DRUG DELIVERY SYSTEM IN HERBAL’S

... novel drug delivery technology is applied in herbal medicine, it may help in increasing the efficacy and reducing the side effects of various herbal compounds and ...of drug delivery in herbal ...

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Non-viral eNOS gene delivery and transfection with stents for the treatment of restenosis

Non-viral eNOS gene delivery and transfection with stents for the treatment of restenosis

... expression viral vector coated on a stent and saw a significant reduction in the neoin- tima-to-media ratio of the experimental stent compared to a bare-metal stent only ...a viral vector coated onto a ...

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“Drug Delivery Research: Current Status and Future Prospects” by Sandhya Murali, Sreeja C Nair, Anu priya, India.

“Drug Delivery Research: Current Status and Future Prospects” by Sandhya Murali, Sreeja C Nair, Anu priya, India.

... controlled drug delivery system is tremendously influencing the pharmaceutical dosage forms, including tablets, capsules, ointments, creams, pills, suppositories, injections etc and it gives effective ...

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NANOSPONGE LOADED HYDROGEL OF CEPHALEXIN FOR TOPICAL DELIVERY

NANOSPONGE LOADED HYDROGEL OF CEPHALEXIN FOR TOPICAL DELIVERY

... The ex-vivo permeation study gives the information about the behaviour of the molecule in-vivo. The amount of drug permeated gives the information about the amount of drug absorbed into the blood. In the ...

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Review: Non-Invasive Therapy for Diabetes Mellitus Using Solid Lipid Nanoparticle

Review: Non-Invasive Therapy for Diabetes Mellitus Using Solid Lipid Nanoparticle

... mucoadhesive drug delivery systems are to extend theresidence time at the site of drug absorption, to intensify contactwith the mucus to increase the drug concentration gradient, toensure ...

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Use of Single-Chain Antibody Derivatives for Targeted Drug Delivery

Use of Single-Chain Antibody Derivatives for Targeted Drug Delivery

... Cell- or tissue-specific antigens provide an opportunity to specifically deliver anticancer drugs to that cell or tissue, without affecting normal cells. One such antigen is the fetal acetylcho- line receptor (fAChR) ...

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