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Non-vitamin K dependent oral anticoagulants

New oral anticoagulants: their advantages and disadvantages compared with vitamin K antagonists in the prevention and treatment of patients with thromboembolic events

New oral anticoagulants: their advantages and disadvantages compared with vitamin K antagonists in the prevention and treatment of patients with thromboembolic events

... and oral anticoagulant vitamin K antagonist (VKA) drugs, the prevention and treatment of venous and arterial thrombotic phenomena remain major medical ...only oral anticoagulants used ...

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Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants

Stroke prevention in the elderly atrial fibrillation patient with comorbid conditions: focus on non-vitamin K antagonist oral anticoagulants

... A study examining edoxaban in ACS patients was planned and then delayed. Studies examining dabigatran in ACS reported increased bleeding risk and have raised concerns regarding an increased risk of MI. The Dabigatran vs ...

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A review of Warfarin woes and non Vitamin k dependent anticoagulants benefits

A review of Warfarin woes and non Vitamin k dependent anticoagulants benefits

... the oral anticoagulant is formation of blot ...the vitamin K metabolism , that been said this reduces the other side effects of using OAC when the choice of anticoagulation therapy is ...

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Setting priorities in the health care sector – the case of oral anticoagulants in nonvalvular atrial fibrillation in Denmark

Setting priorities in the health care sector – the case of oral anticoagulants in nonvalvular atrial fibrillation in Denmark

... The analyses of the cost side in health economic analyses using a budget impact model approach have shown the importance of analyzing costs from a broader cost perspec- tive than just a focus on drug prices. For optimal ...

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High levels of factor IX increase the risk of venous thrombosis

High levels of factor IX increase the risk of venous thrombosis

... oral contraceptive use at the time of thrombosis äs well äs at the time of venipuncture, and high levels of factor VIII, XI, and the vitamin K-dependent clotling factors (all dichotomize[r] ...

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Diagnostic and therapeutic approach in adult patients with traumatic brain injury receiving oral anticoagulant therapy: an Austrian interdisciplinary consensus statement

Diagnostic and therapeutic approach in adult patients with traumatic brain injury receiving oral anticoagulant therapy: an Austrian interdisciplinary consensus statement

... In trauma patients, the efficacy of pharmacological prophylaxis in preventing thromboembolic events is well established [110]. Regarding TBI, the updated Brain Trauma Foundation guideline recommends LMWH or ...

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Vitamin K Deficiency After the Newborn Period

Vitamin K Deficiency After the Newborn Period

... oral vitamin K intakes, expressed as K, activity,. were 0.0 to 8.4 sg/kg/day.[r] ...

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Vitamin K and stability of oral anticoagulant therapy

Vitamin K and stability of oral anticoagulant therapy

... on oral anticoagulants are treated by specialized anticoagulation ...as non-compliance, bleeding episodes, changes in co-medication, hospital visits or (surgical) ...

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Comparison of Oral Anticoagulants

Comparison of Oral Anticoagulants

... of oral anticoagulants has health care professionals questioning how to choose among ...newest anticoagulants are dabigatran (Pradaxa), rivaroxaban (Xarelto), and apixaban ...

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Vitamin K dependent carboxylation and vitamin K metabolism in liver  Effects of warfarin

Vitamin K dependent carboxylation and vitamin K metabolism in liver Effects of warfarin

... in vitamin K-dependent carboxylation and vitamin K metabolism have been extensively studied in rat ...reduced vitamin K1 cofactor for the carboxylation ...of vitamin K1 in ...

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Vitamin K Supplementation with Oral Anticoagulation

Vitamin K Supplementation with Oral Anticoagulation

...  A double-blind RCT - investigating the impact of daily supplementation on stability of anticoagulation in unselected patients on warfarin therapy.  180 patients randomised to vitamin[r] ...

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The Novel Oral Anticoagulants

The Novel Oral Anticoagulants

... amiodarone cimetidine ciprofloxacin citalopram clarithromycin diltiazem enoxacin erythromycin ethinyl estradiol fluvoxamine isoniazid ketoconazole methoxsalen mexiletine nalidixic acid norethindrone norfloxacin ...

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Reliability and validity of the Maltese version of the Perception of Anticoagulant Treatment Questionnaire (PACT-Q)

<p>Reliability and validity of the Maltese version of the Perception of Anticoagulant Treatment Questionnaire (PACT-Q)</p>

... in non-adherence to chronic treatment and there- fore reduced effectiveness, 4,5 speci fi c questionnaires have been developed to assess the satisfaction associated with the anticoagulant ...

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Anti-inflammatory and antiplatelet effects of non-vitamin K antagonist oral anticoagulants in acute phase of ischemic stroke patients

Anti-inflammatory and antiplatelet effects of non-vitamin K antagonist oral anticoagulants in acute phase of ischemic stroke patients

... Recently, non-vitamin K antagonist oral anticoagulants such as direct thrombin and direct factor Xa inhibitors have been prescribed for prevention of embolic ...

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Effectiveness and safety of direct oral anticoagulants versus vitamin K antagonists for people aged 75 years and over with atrial fibrillation : a systematic review and meta-analysis of observational studies

Effectiveness and safety of direct oral anticoagulants versus vitamin K antagonists for people aged 75 years and over with atrial fibrillation : a systematic review and meta-analysis of observational studies

... Data extraction was completed independently and in duplicate by A.M. and A.M.G. using a pre-piloted form in Microsoft Access. Primary effectiveness outcomes of interest were ischaemic stroke and/or systemic embolism. ...

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Role of rivaroxaban in the management of atrial fibrillation: insights from clinical practice

Role of rivaroxaban in the management of atrial fibrillation: insights from clinical practice

... Symptom control and prevention of major complications such as thromboembolism are the two main aims of effective AF management. In preventing stroke and SE, both the ESC and National Institute of Clinical Excellence ...

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Application of prothrombin complex concentrate for reversal of direct oral anticoagulants in clinical practice: indications, patient characteristics and clinical outcomes compared to reversal of vitamin K antagonists

Application of prothrombin complex concentrate for reversal of direct oral anticoagulants in clinical practice: indications, patient characteristics and clinical outcomes compared to reversal of vitamin K antagonists

... or non-traumatic acute bleeding, but only the minority for urgent proce- dures or ...that non-vital interventions can be postponed until the anti- coagulant effect of DOAC has disappeared or until the ...

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Assessment of quality of life, satisfaction with anticoagulation therapy, and adherence to treatment in patients receiving long-course vitamin K antagonists or direct oral anticoagulants for venous thromboembolism

Assessment of quality of life, satisfaction with anticoagulation therapy, and adherence to treatment in patients receiving long-course vitamin K antagonists or direct oral anticoagulants for venous thromboembolism

... versus LMWH-VKA. This raises the question of whether variables are comparable when assessed on different scales. Quality of life after at least 3 months’ treatment was assessed on the EQ-5D questionnaire and on a verbal ...

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Vitamin K deficiency: a case report and review of current guidelines

Vitamin K deficiency: a case report and review of current guidelines

... of vitamin K ...intramuscular vitamin K is refused by parents, an oral dose of 2 mg vitamin K was recom- mended at the time of first feeding, followed by a second dose at ...

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Hereditary combined deficiency of the vitamin K-dependent clotting factors

Hereditary combined deficiency of the vitamin K-dependent clotting factors

... an oral dose of 10 mg twice or three times per week usually avoids frequent muco-cutaneous ...of vitamin K can be regularly administered intravenously at intervals which can vary according to the ...

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