Nonalcoholic fatty liver cell model
Hepatoprotective and antioxidant activities of extracts from Salvia—Nelumbinis naturalis against nonalcoholic steatohepatitis induced by methionine and choline deficient diet in mice
... of model mice, indicating the enhancement of ...in cell membranes, stellate cell activation in the liver leading to liver fibrosis, chronic inflammation, and apoptosis ...aggravates ...
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Insulin Resistance in Egyptian Nonalcoholic Fatty Liver Disease patients
... Homeostasis model assessment of insulin resistance (HOMA-IR) is a simple and useful method for evaluating insulin resistance (or sensitivity) and β cell function, that is calculated from fasting plasma ...
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Original Article Hepatic steatosis causes induction of the chemokine RANTES in the absence of significant hepatic inflammation
... Abstract: Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum ranging from simple steatosis to cirrho- ...both nonalcoholic steatosis and steatohepatitis ...pro-inflammatory ...
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MicroRNAs in Nonalcoholic Fatty Liver Disease
... mediate liver fibrosis in NAFLD, global miRNA sequencing was performed in wedge liver biopsy specimens obtained from bariatric surgery of 15 cases with advanced fibrosis (F3/F4) and 15 cases with no ...
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<p>Therapeutic Effects of Garlic on Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Patients: A Randomized Clinical Trial</p>
... as fatty acid synthase and acetyl coenzyme A (CoA) carboxylase through SREBP1c, as well as up-regulation of the lipolytic gene expression such as PPAR α and ...
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Effects of the Mixture of Cynara cardunculus var scolymus and Cinnamomum zeylanicum on Hepatic Enzymes Activity and Lipid Profiles in Patients with Non-alcoholic Fatty Liver Disease
... mixture, Liver markers of NAFLD including alanin aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphates (ALP), cholesterol (chol), triglycerides (TG), high-density lipoprotein (HDL) and ...
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Prevalence of Abnormal Liver Function Test in Type II Diabetes Mellitus
... Thiazolidinediones. Among the thiazolidinediones, troglitazone was the first to be studied in NASH patients, who showed some biochemical improvement; 29 however, troglitazone was subsequently withdrawn due to ...
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ADAPT: an algorithm incorporating PRO C3 accurately identifies patients with NAFLD and advanced fibrosis
... Non-invasive tests have been proposed as screening tools for detecting advanced liver fibrosis in the general population, where the prevalence of this outcome is low 46 . Score systems such as ADAPT, that exhibit ...
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ADAPT: an algorithm incorporating PRO C3 accurately identifies patients with NAFLD and advanced fibrosis
... The combination of liver stiffness measurement and NAFLD fibrosis score improves the noninvasive diagnostic accuracy for severe liver fibrosis in patients with nonalcoholic fatty liver d[r] ...
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Influence of Gender, Race, and Ethnicity on Suspected Fatty Liver in Obese Adolescents
... 16. Lavine JE, Schwimmer JB. NAFLD/NASH in children. In: Farrell G, George J, Hall P, McCollough A, eds. Fatty Liver Disease: NASH and Related Disorders. Oxford, England: Blackwell Publishing; 2004:229 –240 ...
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Association of calf circumference with insulin resistance and non-alcohol fatty liver disease: the REACTION study
... Nonalcoholic fatty liver disease (NAFLD) is characterized as pathological excessive liver lipid accumulation com- bined with chronic inflammatory state of subjects who without history of ...
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Efficacy and safety of canagliflozin in type 2 diabetes mellitus patients with biopsy-proven nonalcoholic steatohepatitis classified as stage 1–3 fibrosis
... via liver biopsy, n=10) were enrolled and received canagliflozin (100 mg) once a day for 12 ...were liver function/fibrosis markers, metabolic parameters, and ...or liver-related adverse events were ...
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Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in patients with Type 2 Diabetes Mellitus
... GLP-1 receptor agonists (GLP-1RA) may become an at- tractive therapeutic option for the treatment of patients with T2DM and NASH given their broad spectrum of effects on glucose and lipid metabolism. Their structure ...
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Subclinical inflammation in relation to insulin resistance in prediabetic subjects with nonalcoholic fatty liver disease
... the liver due to IR and their consequence in the pathogenesis of NAFLD is not well elucidated, excessive accumulation of triglycer- ides within the hepatocytes induces the release of ROS resulting oxidative ...
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Childhood Adiposity and Nonalcoholic Fatty Liver Disease in Adulthood
... adult liver outcome, participants were categorized into 4 groups based on adiposity status in childhood and adulthood: participants who had normal weight in childhood and were nonobese in adulthood, participants ...
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Resveratrol inhibits nonalcoholic fatty liver disease in rats
... the liver. Liver was weighed, and liver tissue samples taken at the time the rat was killed were immediately placed in 10% buffered formalin and subsequently embedded in ...dividing liver ...
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Effect of Combining Resistance Training and Curcumin Supplementation on liver Enzyme in Inactive Obese and Overweight Females
... on liver enzymes equally ...on liver enzymes and the positive effects of exercises on liver functions ...on liver enzymes and CRP. Eight-week swimming training leads to lower liver ...
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Micronutrients-fortified rapeseed oil improves hepatic lipid accumulation and oxidative stress in rats fed a high-fat diet
... that liver is the main organ for lipid metabolism and its lipid composition and con- tent depend on the ...on liver and result in occurrence of nonalcoholic fatty liver dis- ease ...
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Role of Serum Ck-18 Fragment, Alanine Transaminase and Aspertate Transaminase Level in the Assessment of Fatty Liver Diseases
... Regarding the age, in this study, out of 40 patients, the mean (±SD) age of Group A (= simple fatty liver) patients was 42.63±10.07 (range 30-56) years, Group B (= borderline diagnosis) was 40.06±7.88 ...
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RESEARCH ARTICLE Association of lipid profile and liver enzymes among non alcoholic fatty liver disease patients attending a tertiary care hospital in northern Indian
... from liver cirrhosis, primary biliary cirrhosis, autoimmune hepatitis and alcohol ...study. Liver ultrasound examinations were performed by experienced radiologists who were unaware of the clinical and ...
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