Nordihydroguaiaretic acid
Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-κB-dependent transcription of TNF-α and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA
... Extracts of the Creosote bush, Larrea tridentata, found in deserts of the Southwestern United States and Northern Mexico, have been used for centuries by indigenous peo- ples to treat inflammatory disorders. Many of the ...
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NORDIHYDROGUAIARETIC ACID: DUAL BEHAVIOR AS PRO- OR ANTIOXIDANT ON A EUKARYOTIC CELL MODEL (VERO CELLS).
... Nordihydroguaiaretic acid (NDGA) is a natural phenolic compound, specifically defined as lignan, which has shown to have promising applications in the treatment of multiple diseases, including ...
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Long chain polyunsaturated fatty acids (LCPUFAs) and nordihydroguaiaretic acid (NDGA) modulate metabolic and inflammatory markers in a spontaneous type 2 diabetes mellitus model (Stillman Salgado rats)
... without nordihydroguaiaretic acid (NDGA), and studied their effects on metabolic and inflammatory ...arachidonic acid), react- ive oxygen species (ROS) and other related ...
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Inhibition of Microbially-induced Inflammation by the Naturally Occurring Plant Compounds Tetra-O-methyl nordihydroguaiaretic acid (terameprocol) and Berberine.
... Extracts of the Creosote bush, Larrea tridentata, found in deserts of the Southwestern United States and Northern Mexico, have been used for centuries by indigenous peoples to treat inflammatory disorders. Many of the ...
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Nordihydroguaiaretic acid impairs prostate cancer cell migration and tumor metastasis by suppressing neuropilin 1
... Tumor metastasis is a major cause leading to the deaths of cancer patients. Nordihydroguaiaretic acid (NDGA) is a natural product that has been demonstrated to show therapeutic values in multiple diseases. ...
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Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines
... Background: Extracts of the creosote bush, Larrea tridentata, have been used for centuries by natives of western American and Mexican deserts to treat a variety of infectious diseases and inflammatory disorders. The ...
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Diabetic encephalopathy: beneficial effects of supplementation with fatty acids ω3 and nordihydroguaiaretic acid in a spontaneous diabetes rat model
... palmitic acid (PA) which are present in red meat, plays a critical role in the inhibition of the insulin signalling pathway and induction of endo- plasmic reticulum (ER) stress in several tissues including ...
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Resistance to type 1 diabetes induction in 12 lipoxygenase knockout mice
... droguaiaretic acid, a lipoxygenase inhibitor, protected rat islets from cytokine-induced destruction ...that nordihydroguaiaretic acid, a prefer- ential lipoxygenase inhibitor, inhibited ...
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A study of the fatty acid profile in the muscle of Monopterus chuchia
... palmitoleic acid. It is biosynthesized from palmitic acid, which is also detected in this fish ...Palmitoleic acid is present in considerable amount in Monopterus ...fatty acid which increases ...
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“Antioxidant and Antimicrobial Potentiality of Quantitatively Analysed Ethanol Extract from Macrocybe crassum” by Somanjana Khatua, Krishnendu Acharya, India.
... vanillic acid and p-coumaric acid have antibacterial effect against ...p-coumaric acid can inhibit ...p-coumaric acid and caffeic acid. 5 Vanillic acid and p- coumaric ...
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Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of action
... caffeic acid may bind to the AhR, being an inhibitor of its action, thus decreasing the transcription and activity of CYP1A1, both in basal and TCDD-treated ...
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ANTI-INFLAMMATORY ACTIVITY OF B.TOMENTOSA (ROOT, BARK) AND B. VAHLII (ROOT)
... The anti-inflammatory activity was determined using the 5-Lipoxygenase assay (LOX) (Baylac and Racine, 2003; Kamatou et al., 2009; Vieira et al., 2001). 5- Lipoxygenases (LOX) are dioxygenases that catalyse the addition ...
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ANTIBACTERIAL ACTIVITY AND GCMS ANALYSIS OF THE EXTRACT OF LEAVES OF RHIZOPHORA APICULATA (A MANGROVE PLANT)
... Ursolic acid was reported to be cytotoxic against A- 549, L-1210 and KB tumour cells (Yamagishi et ...oic acid was found to exhibit anti-ulcer properties (Fourie et ...palmitic acid as major ...
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Mechanistic and stereochemical studies on methylaspartase and glutamate mutase
... 3-methylaspartic acid, was scrambled during the glutamate mutase catalysed rearrangement, probably by rapid rotation of the methylene radical ...(2S,3S)-3-Ethylaspartic acid (117) or 3-fluoromethylaspartic ...
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... oleic acid (an omega-9 fatty acid), 24% is linoleic acid (a poly unsaturated omega 6 essential fatty acid) and 6% is palmitic acid (a saturated fatty acid) ...arachidic ...
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Formation of carboxylic acids during degradation of monosaccharides
... The formation of low molecular carboxylic and hydroxycarboxylic acids as well as sugar and deoxysugar acids from monosaccharides (d-glucose, d-fructose, d-arabinose, dl-glyceraldehyde, and 1,3-dihydroxyacetone) was ...
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In Vitro Metabolite Colonic Production from Otili (Sphenostylis stenocarpa) as Influenced by Selected Gastrointestinal Microbes
... caproic acid, lauric acid, palmitelaidic acid, palmitic acid caprylic acid, erucic in this study is very interesting aspect of contribution to the existing ...mitic acid and 56% ...
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Production of medium-chain carboxylic acids by Megasphaera sp. MH with supplemental electron acceptors
... after sterilization by filtration and argon purging. The mPYF medium, containing fructose instead of glucose in the mPYG medium, was used for maintenance of the iso- lated strain and for the production of C5–C8 saturated ...
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Hydroxybenzoic acid isomers and the cardiovascular system
... Gentisic acid like aspirin inhibits prostaglandin formation in response to lipopolysaccharides [46], presumably via inhibiting COX ...gentisic acid may help decrease the probability of heart at- tacks due ...
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Construction of DGLA producing cell factory by genetic modification of Mucor circinelloides
... fatty acid biosynthetic pathway was done in Saccharomyces cerevisiae and Aspergillus oryzae for DGLA production but its concentration was low (less than 3%) [1, ...
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