novel therapies
EXISTING AND NOVEL THERAPIES FOR PSORIASIS
... existing therapies, the novel therapies such as anticytokines, small molecule inhibitor, NGF inhibitor, and corticosteroids [81] and other therapies became more prevalent in recent years for ...
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Malignant Pleural Mesothelioma: Treatment Options and Novel Therapies
... Malignant pleural mesothelioma is a rare primary tumor rising from the pleura and is associated with exposure to asbestos fibers. Mesothelioma is a locally aggressive disease that usually presents at an advanced stage ...
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Emerging novel therapies in the treatment of castrate resistant prostate cancer
... CUAJ ? April 2011 ? Volume 5, Issue 2 ? 2011 Canadian Urological Association Emerging novel therapies in the treatment of castrate resistant prostate cancer review 120 Alym Abdulla, MD; Anil Kapoor, M[.] ...
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Synthetic lethality: the road to novel therapies for breast cancer.
... BRCA1/2 gene mutation, making this PARP inhibitor not only the first synthetic lethal. 297[r] ...
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Novel therapies in genitourinary cancer: an update
... of novel therapeutic agents. Here we will mainly focus on novel agents with activity for ...of novel agents in the treatment of CRPC (efficacy data summarized in Table ...
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Gout Novel therapies for treatment of gout and hyperuricemia
... uricase therapies have the potential to induce oxidative stress, since degradation of the high micromolar plasma concentrations of urate in gout patients by uricases has the capacity to generate substantial ...
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Molecular regulation of HDL metabolism and function: implications for novel therapies
... HDL metabolism represents a major target for the development of therapies intended to reduce the risk of atherosclerotic cardiovascular disease. HDL metabolism is complex and involves dissociation of HDL ...
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Characterisation of novel therapies to mitigate inflammation in retinal degenerations
... NIR therapies have been useful in treating a number of cardiovascular [326], musculoskeletal [218, 219] and central nervous system (CNS) conditions [220, 221], with studies in animal models showing positive ...
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Alternative pre approved and novel therapies for the treatment of anthrax
... Background: Bacillus anthracis, the causative agent of anthrax, is a spore forming and toxin producing rod-shaped bacterium that is classified as a category A bioterror agent. This pathogenic microbe can be transmitted ...
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Schizophrenia: Neural Mechanisms for Novel Therapies
... that is a partial agonist at the glycine site, is effective also. Subtle interactions between GABA- and glutamate-contain- ing neurons may clarify mechanisms of PCP psychosis and facili- tate antipsychotic drug ...
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Novel therapies for treating atrial fibrillation
... While dronedarone is similar to amiodarone in its mode of action, there are other novel anti-arrhythmic agents that are amiodarone-derivatives, such as celivarone. Celi- varone, like dronedarone, is noniodinated ...
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Medical treatment of Cushing's disease: Overview and recent findings
... Abstract: Cushing’s disease, due to pituitary adrenocorticotropic hormone (ACTH) hypersecretion, is the most common etiology of spontaneous excess cortisol production. The majority of pituitary tumors causing Cushing’s ...
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Considerations for payers in managing hormone receptor-positive advanced breast cancer
... Despite many advances in screening and treatment, BC is one of the most common causes of cancer-related death, and advanced disease has a particularly poor prognosis. The direct cost of $16.5 billion associated with BC ...
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Novel oncolytic viral therapies in patients with thoracic malignancies
... Oncolytic virotherapies are under active investigation in lung cancer and mesothelioma both in vitro and in vivo. Replication-competent viruses show great promise for treatment in thoracic cancers in the coming decade. ...
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Novel targeted therapies for mantle cell lymphoma
... In summary, MCL is an aggressive B-cell malignancy which is incurable with standard therapies. While the response rate to initial therapy is high, patients invariably relapse, with a tendency toward lower response ...
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Conventional and novel stem cell based therapies for androgenic alopecia
... Abstract: The prevalence of androgenic alopecia (AGA) increases with age and it affects both men and women. Patients diagnosed with AGA may experience decreased quality of life, depression, and feel self-conscious. There ...
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<p>Sorcin: a novel potential target in therapies of cancers</p>
... The fi ndings shed light on the relationship between sorcin and CSCs. 47 However, the issue of whether sorcin can directly or indirectly in fl uence the event remains resolved. Also, sorcin can regulate VEGF, which is a ...
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A Novel Approach to Understanding Stress, Trauma, and Bodymind Therapies
... In our discussion of maladaptive PS above, we referred to “biolog- ical completion.” This involves the completion, through imagery or safe re-enactment, of the impulses of the persistent maladap- tive PS. Several forms ...
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ZINC OXIDE NANOPARTICLES AS POTENTIAL NOVEL ANTICANCER THERAPIES
... photodynamic therapies (PDT) exist, but suffer from a need to be excited by light in either the visible or UV spectrum, which cannot readily penetrate into ...
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Novel experimental therapies for atherosclerosis : a genomics based approach
... Our lab has demonstrated that vaccination against VEGFR2 inhibits lesion formation in LDL receptor deficient mice by the generation of CD8 + VEGF specific CTL’s that remove activated[r] ...
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