nuclear factor kappa-light-chain enhancer of activated B cells
Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence
... growth factor receptor; FOXO, forkhead box; iGF1R, insulin like growth factor 1 receptor; HMGB1, high mobility group protein B1; iKK, ikB kinase; iL, interleukin; iR, insulin receptor; MAPK, mitogen ...
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Significance of glioma associated oncogene homolog 1 (GLI1)expression in claudin low breast cancer and crosstalk with the nuclear factor kappa light chain enhancer of activated B cells (NFκB) pathway
... In vertebrates, canonical Hedgehog (Hh) pathway sig- nal transduction occurs when one of the three ligands, Sonic, Indian, or Desert hedgehog, binds to the receptor Patched-1 (PTCH1) or its homolog, Patched-2. In the ...
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Curcumin prevents muscle damage by regulating NF-kB and Nrf2 pathways and improves performance: an in vivo model
... as nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB), nuclear factor (erythroid-derived 2)-like 2 (Nrf2)/ hemeoxygenase-1 ...
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Lambertianic Acid Sensitizes Non-Small Cell Lung Cancers to TRAIL-Induced Apoptosis Via Inhibition of XIAP/NF-kB and Activation of Caspases and Death Receptor 4
... H1299 cells compared to LA or TRAIL ...as B-cell lymphoma 2 (Bcl-2), Fas-like inhibitor protein (FLIP) and X-linked inhibitor of apoptosis protein (XIAP) and enhanced the activation of pro-apoptotic ...
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Original Article EGCG suppresses NF- B activation induced by gastroesophageal reflux contents in human esophageal epithelial cells
... the nuclear factor kappa-light-chain- enhancer of activated B cells (NF-κB) signaling pathway in normal human esophageal epithelial cells (HEECs) and ...
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IAP proteins as targets for drug development in oncology
... IκBα, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; IAPs, inhibitors of apoptosis; IL, interleukin; IKK, IκB kinase complex; LUBAC, ...
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A new piece of an old puzzle: lack of association between C-Rel (rs13031237-rs842647) single nucleotide polymorphisms and non-segmental vitiligo
... : Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor alpha; IKKb: Inhibitor of nuclear factor kappa-B kinase; IL: ...
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Hyaluronic acid abrogates ethanol-dependent inhibition of collagen biosynthesis in cultured human fibroblasts
... growth factor 1 receptor (IGF-IR), phosphorylated mitogen-activated protein kinases (MAPKs: ERK 1 /ERK 2 ), protein kinase B (Akt), nuclear factor kappa- ...
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Original Article Impact of Bay 11-7085 on radiosensitivity of pancreatic cancer cell line Sw1990
... [4] nuclear factor kappa light chain enhancer of activated B cells (NF-κB) plays an important role in the development of resistance to radio- therapy in ...
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Anti-inflammatory effects of prunin on UVB-irradiated human keratinocytes
... transcription factor nuclear factor kappa-light-chain-enhancer of activated B cells (NF- κ B) in response to stimuli such as lipopolysaccharide ...
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Inhibition of osteoclastogenesis by RNA interference targeting RANK
... NF-kappa B: Nuclear factor `kappa-light-chain-enhancer` of activated B-cells; RANK: Receptor activator of NF- kappa B; RANKL: ...
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Activated transcription factor nuclear factor kappa B is present in the atherosclerotic lesion
... muscle cells and macrophages and to a lesser ex- tent T cells was identified in the advanced atherosclerotic le- sions which we examined in this ...muscle cells and mac- rophages as the most ...
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Rel/Nuclear factor-kappa B apoptosis pathways in human cervical cancer cells
... κ B as a factor in both cancerous and normal cell survival is well ...κ B to be activated in the early malignant transformation of mammary cells of the breast ...κ B is ...
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Deubiquitinases in cancer
... [81], B-cell CLL/lymphoma 3 (Bcl-3) [82] and mitogen- activated protein kinases [83], whereas A20 promotes the degradation of TRAF2 in lysosomes by means of its own E3 ligase activity ...ubiquitin ...
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Arenavirus Nucleoproteins Prevent Activation of Nuclear Factor Kappa B
... B and activator protein 1 (AP-1), whereas later induction of IFN-␣ forms is mainly dependent on IRF7 and, to a lesser extent, IRF3 (20, 28, ... B comprises a family of tran- scription factors found ...
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Human Trophoblast Cells Modulate Endometrial Cells Nuclear Factor kappa B Response to Flagellin In Vitro
... be activated not only by their specific pathogen-associated molecular pattern (PAMPs) but also by endogenous ligands, such as Heat- shock proteins, fibronectin, fibrinogen, surfactant protein-A, heparan sulphate, ...
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SLUG is activated by nuclear factor kappa B and confers human alveolar epithelial A549 cells resistance to tumor necrosis factor alpha induced apoptosis
... cancer cells through increased activity of metalloproteinase-2 and suppression of E-cadherin ...(MM) cells in the presence of stem cell factor (SCF) up-regulated SLUG and increased resistance to the ...
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Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis like systemic inflammatory response in mice
... of nuclear factor kappa B (NFB) and mitogen-activated protein kinases (MAPKs) [extracellular related kinase (ERK) and c-jun-NH2 terminal kinase (JNK)], the production of cytokines ...
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Salubrinal abrogates palmitate-induced leptin resistance and endoplasmic reticulum stress via nuclear factor kappa-light-chain-enhancer of activated B cell pathway in mHypoE-44 hypothalamic neurons
... κ B p65 (1:1,000, #8242), anti- Lamin B1 (1:1,000, #13435), anti-phospho-I κ B α (1:1,000, #2859), anti-I κ B α (1:1,000,#9242), and anti- β -Actin (1:5,000, #3700) from Cell Signaling Technology ...
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Nuclear factor kappa B interacts functionally with the platelet derived growth factor B chain shear stress response element in vascular endothelial cells exposed to fluid shear stress
... PDGF B-chain, whose expression is modulated by shear ...the nuclear protein(s) binding to this element has not yet been ...that nuclear factor-kappa B p50-p65 ...
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