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Nucleic acid structure

The Proteomic Code: a molecular recognition code for proteins

The Proteomic Code: a molecular recognition code for proteins

... and Nucleic Acids [52] indicated that the second codon resi- due is intimately coupled with the known physico-chem- ical properties of the amino ...in nucleic acids and forms the nucleic acid ...

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Targeting Nucleic Acid Junctions Using Triptycene-Based Molecules

Targeting Nucleic Acid Junctions Using Triptycene-Based Molecules

... Targeting nucleic acids in a structure- or sequence-specific manner with small molecules remains a significant challenge in chemical ...particular nucleic acid structure would allow for ...

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Correlation between nucleotide composition and folding energy of coding sequences with special attention to wobble bases

Correlation between nucleotide composition and folding energy of coding sequences with special attention to wobble bases

... of nucleic acid structure even more interesting, because it indicates that the excess information in the redundant codon (carried by the wobble bases) may be used to mod- ify or regulate the protein ...

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Functional nucleic acid probes and uses thereof

Functional nucleic acid probes and uses thereof

... functional nucleic acid probes, and methods of using functional nucleic acid probes, for binding a target to carry out a desired ...functional nucleic acid, at least one ...

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An Introduction to Peptide Nucleic Acid

An Introduction to Peptide Nucleic Acid

... dimensional structure of four PNA complexes have been determined so far (Figure ...its nucleic acid partner, as the RNA strand in the RNA/PNA duplex is essentially in a A-form conformation, while the ...

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Syntheses and Structure Elucidations of Ternary Metal [Cu/Co] Complexes with Nucleic Acid Constituents

Syntheses and Structure Elucidations of Ternary Metal [Cu/Co] Complexes with Nucleic Acid Constituents

... The structure is stabilized through the extensive network of N-H···O, C-H···O and O-H···O hydrogen bond interactions between the water molecules and polymerizing, making the sheets to run in third ...

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PARTIAL PURIFICATION AND SOME PROPERTIES OF NUCLEOLYTIC ENZYMES FROM MOTH BEAN (PHASEOLUS ACONITIFOLIOS) ALKA MANGALEKAR AND SHUBHANGI SONTAKKE*

PARTIAL PURIFICATION AND SOME PROPERTIES OF NUCLEOLYTIC ENZYMES FROM MOTH BEAN (PHASEOLUS ACONITIFOLIOS) ALKA MANGALEKAR AND SHUBHANGI SONTAKKE*

... (1969) Enzymes of nucleic acid metabolism from wheat seedlings; Purification and general properties of associated DNase, and RNase and 3'-nucleoti­ dase activity. Structure an[r] ...

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Immunogenicity of porcine circovirus type 2 nucleic acid vaccine containing CpG motif for mice

Immunogenicity of porcine circovirus type 2 nucleic acid vaccine containing CpG motif for mice

... Nucleic acid vaccine is one of the hot spot of PCV2 vaccine ...PCV2 Nucleic acid vaccine was first re- ported by Kamstrup [16], they developed and investigated the potential of DNA vaccination ...

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Investigations of nonhistone chromosomal proteins

Investigations of nonhistone chromosomal proteins

... These observations suggest that the major NHC proteins play a general role in chromatin structure and the regulation of genome expression; several may be enzymes of nucleic acid and hist[r] ...

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Rapid purification of hepatitis B virus DNA from serum

Rapid purification of hepatitis B virus DNA from serum

... The complex genome structure of HBV, together with the laborious purification procedure of its nucleic acid NA frequently involving ultracentrifugation of serum, in vitro repair by the v[r] ...

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Elucidating Ubiquitin Chain Formation Catalyzed by E2 Enzymes through use of a Di Ubiquitin Probe

Elucidating Ubiquitin Chain Formation Catalyzed by E2 Enzymes through use of a Di Ubiquitin Probe

... Therefore, nucleic acids related research is essential for better understanding of diseases and identifying novel drug candidate and target for the development of therapeutics with high efficiency to treat some ...

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The relation between cell wall protein and nucleic acid synthesis in tall pea plants treated with a growth retardant AMO-1618.

The relation between cell wall protein and nucleic acid synthesis in tall pea plants treated with a growth retardant AMO-1618.

... minutes. The extract was then incubated with 5 ml of 5% HCIO^ at 70°C for 40 minutes and then centrifuged. The supernatant was collected. The insoluble pellet was washed once with 1 ml 5% H610^, by centrifuging; this ...

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Whole body composition of Xenopus laevis larvae: implications for lean body mass during development

Whole body composition of Xenopus laevis larvae: implications for lean body mass during development

... substrate turnover, energy stores, oxygen consumption and other physiological measures. Whole-animal composition was determined during development from eggs (NF stage 1) to 2 weeks post-feeding (NF 50–51), which ...

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Nucleic acid chaperons: a theory of an RNA-assisted protein folding

Nucleic acid chaperons: a theory of an RNA-assisted protein folding

... The possibility that the nucleotide sequence itself could modulate translation and hence affect co-translational folding and assembly of proteins has been investigated in a number of studies [5-7]. Studies on the ...

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Algorithms for nucleic acid sequence design

Algorithms for nucleic acid sequence design

... hierarchical structure decomposition and defect-weighted sampling to our ensemble defect optimization algorithm by comparing performance to three modified algorithms lacking one or both ...

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Virion nucleic acid of Ebola virus.

Virion nucleic acid of Ebola virus.

... At the outset of this project, no data were available on the nature of the Ebola virus genome, and our analysis considers whether i the virion nucleic acid is RNA or DNA, ii the genome i[r] ...

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PNA Biosensors for Nucleic Acid Detection

PNA Biosensors for Nucleic Acid Detection

... depends primarily on the selection of the probe, and secondarily upon the hybridization conditions (mainly the temperature). To date, however, most DNA biosensors are not capable of selectively discriminating against ...

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Search for a Prion-Specific Nucleic Acid

Search for a Prion-Specific Nucleic Acid

... Studies of synthetic prions combined with investigations of naturally occurring strains support the thesis that prions are devoid of a prion-specific nucleic acid. A novel strain of prions was produced ...

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Aptamers: Diagnostic and Therapeutic Applications

Aptamers: Diagnostic and Therapeutic Applications

... biosensors could have been applied as a promising approach to some specific issues. They could be used for cheap diagnosis at an early stage of the disease, i.e., immediately after exposure to the pathogen, as well as to ...

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Properties of Maedi Nucleic Acid and the Presence of Ribonucleic Acid- and Deoxyribonucleic Acid-Dependent Deoxyribonucleic Acid Polymerase in the Virions

Properties of Maedi Nucleic Acid and the Presence of Ribonucleic Acid- and Deoxyribonucleic Acid-Dependent Deoxyribonucleic Acid Polymerase in the Virions

... Properties of Maedi Nucleic Acid and the Presence of Ribonucleic Acid- and Deoxyribonucleic Acid-Dependent Deoxyribonucleic Acid Polymerase in the Virions Received for publication 22 Mar[r] ...

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