OA, osteoarthritis
Relative benefit risk comparing diclofenac to other traditional non steroidal anti inflammatory drugs and cyclooxygenase 2 inhibitors in patients with osteoarthritis or rheumatoid arthritis: a network meta analysis
... drugs; OA: osteoarthritis; PGA: patient global assessment; PICOS: population, intervention, comparators, outcomes, and study design; pyrs: patient years; RA: rheumatoid arthritis; RCTs: randomised ...
18
<p>Downregulation of miR-34a Promotes Proliferation and Inhibits Apoptosis of Rat Osteoarthritic Cartilage Cells by Activating PI3K/Akt Pathway</p>
... of osteoarthritis was constructed and knee joint cartilage cells were isolated in ...(34aI), osteoarthritis model (OA), osteoarthritis model + negative control (OA + NC) and ...
13
Walking ability during daily life in patients with osteoarthritis of the knee or the hip and lumbar spinal stenosis: a cross sectional study
... knee OA, hip OA and LSS and 30 healthy control individuals with a comparable age and gender distribu- tion (Table ...with OA the grade of OA was 3 or higher according to the Kellgren-Lawrence ...
7
DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management?
... Qualitative results of reverse transcription-polymerase chain reactions (PCRs) using DREAM primer and DREAM nested primer. (a) DREAM amplicons of 409 base pairs (bp) in size in total RNA derived from cer- ebellum and ...
8
Gene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts
... than OA samples (Figures 5a and 6a), and the strongest dose-dependent downregulation was observed in the case of Hc-gp 39 ...in OA (Figure ...in OA (Figure ...in OA it did not have an ...in ...
13
The relationship between reductions in knee loading and immediate pain response whilst wearing lateral wedged insoles in knee osteoarthritis
... Understanding the failure of lateral wedge insoles to reduce knee pain offers an opportunity to develop treatments that are effective either by producing consistent reductions in medial load, larger average reductions in ...
9
The relationship between reductions in knee loading and immediate pain response whilst wearing lateral wedged insoles in knee osteoarthritis
... Understanding the failure of lateral wedge insoles to reduce knee pain offers an opportunity to develop treatments that are effective either by producing consistent reductions in medial load, larger average reductions in ...
8
Pre-operative ambulatory measurement of asymmetric lower limb loading during walking in total hip arthroplasty patients
... THA; Osteoarthritis: OA; Instrumented Force Shoes: IFS; Harris Hip Score: HHS; Traditional Western Ontario and McMaster Universities osteoarthritis index: WOMAC; Medical Ethics Committee: METC; Gait ...
10
Effects of ultrasound therapy on the synovial fluid proteome in a rabbit surgery-induced model of knee osteoarthritis
... PONs include PON1, PON2 and PON3, and they resist the oxidation of low density lipoprotein (LDL). PON1 hydrolyzes paraoxon. Some studies have indicated decreased PON1 expression after treatment of HepG2 cells with oxydic ...
15
Physical therapy vs internet based exercise training (PATH IN) for patients with knee osteoarthritis: study protocol of a randomized controlled trial
... of OA symptom severity and incorporating minimal exclu- sion criteria ...knee OA, primary care and specialty physicians who treat patients with knee OA, physical therapists, and representatives of ...
12
Quantitative evaluation in combination with nonquantitative evaluation in early patellar cartilage osteoarthritis at 3.0 T
... A total of 36 men and 34 women with a total of 92 knee joint cases were enrolled in this study. Written informed consent was obtained from all the participants before the study, according to the requirements of the ...
11
Evaluation of clinical symptoms and sonographic characteristics of femoral trochlear cartilage in primary knee osteoarthritis
... knee OA according to the American College of Rheumatology criteria with a visual analog scale pain score of 30 mm or ...Universities Osteoarthritis Index (WOMAC) criteria, and a radiologist performed ...
5
Reproducibility of range of motion and muscle strength measurements in patients with hip osteoarthritis – an inter rater study
... is osteoarthritis (OA) ...of OA [1], radio- graphs are not recommended solely for just confirming the ...hip OA besides pain are reduced ROM [5-8] and muscle strength ...hip OA [2,12] ...
10
Comparison of general practitioners and rheumatologists' prescription patterns for patients with knee osteoarthritis
... knee OA increases with age, the safety of prescribed drugs deserves special consid- eration, and the benefits and risks of prescribing non- steroidal anti-inflammatory drugs (NSAIDs) must be cautiously evaluated ...
6
Efficacy and safety of non-pharmacological, pharmacological and surgical treatment for hand osteoarthritis: a systematic literature review informing the 2018 update of the EULAR recommendations for the management of hand osteoarthritis
... hand osteoarthritis (OA), a systematic literature review was performed up to June 2017, including (randomised) controlled trials or Cochrane systematic ...base OA appeared more effective than ...
18
The efficacy and safety of S-flurbiprofen plaster in the treatment of knee osteoarthritis: a phase II, randomized, double-blind, placebo-controlled, dose-finding study
... Background: Nonsteroidal anti-inflammatory drug (NSAID) patches are convenient for use and show much less gastrointestinal side effects than oral NSAIDs, whereas its percutaneous absorp- tion is not sufficient for the ...
14
5% Ibuprofen Iontophoresis Compared with Transcutaneous Electrical Nerve Stimulation in the Management of Knee Osteoarthritis: A Feasibility Study
... The treatment responses emanated from patients with the use of 5% Ibuprofen iontophoresis followed similar trend as found in the earlier studies [8] [17] [18]. Xiaoying et al., reported that iontophoresis facilitated ...
8
Magnetic resonance evaluation in long term follow up of operated lateral tibial plateau fractures
... Twenty-three patients undergoing open reduction and internal fixation for 24 TPFs (displaced B- and C-type fractures according to the AO/ASIF classification) were treated with the same fork-shaped plate (Ulrich GmbH ...
7
Translation of clinical problems in osteoarthritis into pathophysiological research goals
... on OA from a researcher ’ s point of view is not always aligned with the perspective of a patient with ...on OA mainly on abnormalities in structure and function while patients consider OA as a ...
5
Changes in viscoelastic properties of articular cartilage in early stage of osteoarthritis, as determined by optical coherence tomography based strain rate tomography
... Our results indicate that viscoelastic properties are de- graded in the deep layer around the tidemark as cartilage degeneration progresses. Previous reports have shown that the equilibrium confined compression modulus ...
10