oestrogen receptors
Localisation of oestrogen receptors (ERalpha and ERbeta) in the human and rat epididymides
... The aim of the study was to compare the localisation of oestrogen receptors a and b (ER a and ER b ) in the human and rat epididymides. In the human epididy- mis the immunoexpression for ERa was detected in ...
6
Probing the link between oestrogen receptors and oesophageal cancer
... of oestrogen receptors (ER) in oesophageal cancer has been debated for several years but the significance of the receptors in this cancer remains ...
10
Oestrogen receptors in the human and primate testis and reproductive tract
... 44.. a) ERcx immunopositive staining of ED from macaque, note intense positive staining in the epithelial cells ; b) Marmoset seminal vesicle, ERcc positive cells are found onl[r] ...
8
Interactions between oestrogen and 1α,25(OH)2-vitamin D3 signalling and their roles in spermatogenesis and spermatozoa functions
... of oestrogen are ...in oestrogen signalling pathway of motility, knowing that oestrogen receptors ESR1 and ESR2 are mainly described on flagellum [9, 11, 14] and without hypothesis of molecu- ...
14
Transcriptional activation by the mouse oestrogen receptor
... mouse oestrogen receptor M-532R and L-529A/M-532A/C-534A/V-537A (described in chapter 5) and two mutants of the human oestrogen receptor (Pakdel and Katzenellenbogen, 1992), that contained substitutions of ...
216
Oestrogen is bad for patients with breast cancer?
... with oestrogen receptors (ERs) will respond to ovarian ablation ...reason, oestrogen is considered bad for patients with breast ...synthetic oestrogen administration was found to be effective ...
5
Association between HER-2/neu over-expression and clinico-pathologic parameters of breast cancer in northern Malaysia
... progesterone receptors form an important part of breast cancer management. Oestrogen and progesterone receptor examination is recommended for prediction of response to hormonal ...less receptors in ...
5
Association of BPA and Environmental oestrogen with Diabetes mellitus
... Bisphenol A (BPA) is a contaminant which, increasing exposure to, exerts both toxic and estrogenic effects on mammalian cells. Exposure to endocrine disrupting chemicals (EDCs) such as BPA is of concern because they ...
5
Mise au point Estrogènes et reproduction chez le mâle
... : Localisation of cytochrome P450 aromatase and oestrogen receptors c~ and 13 in bank vole testicular cells.. : Effect oftes- tosterone and estradiol in a man with aromatase[r] ...
7
Differences in oestrogen and progesterone receptors, HER-2, p53 expression and proliferation in ductal breast cancers in relation to histopathological grade
... of oestrogen and progesterone receptors falls within the first category of prognostic factors according to the College of American ...of oestrogen receptors (ER), progesterone receptors ...
7
Oestrogen exposure and breast cancer risk
... So far there have been more than 60 analytical studies investigating the relationship between menopausal HRT and breast cancer risk. Data from these studies were brought together in a pooled analysis [7], which found ...
9
Nongenomic oestrogen signalling in oestrogen receptor negative breast cancer cells: a role for the angiotensin II receptor AT1
... mediate oestrogen-induced activation of ade- nylate cyclase via the Gs protein ...attractive oestrogen-signalling GPCR ...enomic oestrogen signalling in ER-negative cells, we knocked down AT1 ...
10
The Role of Neurotransmitters in Anesthesia
... It is one of the major inhibitory neurotransmitters in posterior areas of the central nervous system, spinal cord, brainstem, and retina. In the spinal cord and brain stem, glycinergic interneurones provide an inhibitory ...
10
Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling
... Next, we investigated Notch signalling as another likely paracrine pathway since it has been reported [21] and we confirm here that Notch1 signalling activity increases fol- lowing exposure to oestrogen (Figure ...
12
Transcriptional activation and dimerisation properties of oestrogen receptor β
... the oestrogen receptor (ER) w as first used to identify receptor interacting p roteins (RIP) in far- w estern blotting experim ents, two pred o m in an t bands of 160 and 140 kDa w ere observed (Cavaillès et al ...
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Oestrogen deficiency modulates particle induced osteolysis
... of 100 ms. Eight frames were averaged for each rota- tion increment of 0.9° to increase the signal to noise ratio. 3D images were reconstructed with a voxel aver- age size of 10 μm, using the manufacturer reconstruc- ...
12
G PROTEIN COUPLED RECEPTORS A POTENTIAL NEW DRUG TARGET TO COMBAT DIABETIC SYNDROME: AN OVERVIEW
... pheromone receptors), class E (Cyclic AMP receptors) and class F (Frizzled/Smoothened) 6 ...protein-coupled receptors 9 , about 350 of which detect hormones, growth factors and other endogenous ...
11
Oestrogen receptor alpha in pulmonary hypertension
... that oestrogen may mediate proliferation of hPASMCs and may contribute to PAH ...that oestrogen can induce proliferation of hPASMCs via ERa ...of oestrogen is dependent on activation of downstream ...
11
Progesterone receptors animal models and cell signaling in breast cancer: The role of oestrogen and progesterone receptors in human mammary development and tumorigenesis
... Steroid hormones such as oestradiol and progesterone are lipophilic and they enter cells and their nuclei primarily by diffusing through the plasma and nuclear membranes. Once in the nucleus, the steroids encounter ...
5
The oestrogen paradox: an hypothesis
... with oestrogen alone for 5 to 9 years unexpectedly experienced a decrease in the risk for breast cancer ...short-term oestrogen use decreases the risk for breast cancer whereas long-term use increases ...
5