Oral Granisetron
Oral Granisetron in the prevention of Post Operative Vomiting in Adenotonsillectomies
... One source identifies increased duration as surgery and anesthesia lasting more than 1 hour It is important to note that although the type of anesthesia and surgery is often implicated i[r] ...
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Use and cardiovascular safety of transdermal and other granisetron preparations in cancer management
... during oral dosing, and approximately the same C max was achieved each ...after oral dosing compared to patch administration, mean plasma concentration through 5 days was ...of oral ...
7
Comparison of Granisetron with the combination of Granisetron and Dexamethasone in the Prophylaxis of Post Operative Nausea and Vomiting
... and oral granisetron has been evaluated in more than 7,000 patients in clinical trial, which have shown the drug to be well tolerated, with mild and transient side ...or oral granisetron for ...
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Use of granisetron transdermal system in the prevention of chemotherapy-induced nausea and vomiting: a review
... of oral granisetron, administered every day during the same period of ...transdermal granisetron in chemotherapy-induced nausea and vomiting, in patients receiving moderately and highly emetogenic ...
12
Randomized Double Blind Trial to Compare the Efficacy of Granisetron And Ondansetron in Controlling Emesis in Children with Acute Lymphoblastic Leukemia
... and granisetron (30) group based on the random ...(oral granisetron 1mg tablet and oral ondansetron 4mg tablet) was crushed and stored in an eppendorph with randomized ...
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Use of transdermal and intravenous granisetron and the ability of the Hesketh score to assess nausea and vomiting induced by multiday chemotherapy
... versus oral granisetron in patients receiving 3 days of multi- agent moderately or highly emetogenic chemotherapy, regardless of granisetron ...
6
Review Article Prophylactic granisetron for prevention of postoperative shivering: a meta-analysis of randomized controlled trials
... However, the current meta-analysis had several limitations. First, the total number of trails included was significant, but the amounts in subgroups were too small to secure conclusive results. In addition, significant ...
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A randomized, double blind trial of Granisetron compared with Dexamethasone in preventing Postoperative Nausea and Vomiting after laparoscopic abdominal surgery at a tertiary care hospital
... of Granisetron provided an overall superior antiemetic efficacy than dexamethasone in terms of PONV scores at different intervals of time and the incidence of use rescue medications after laparoscopic abdominal ...
5
Comparative efficacy of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis
... were granisetron versus placebo (OR, ...0.09–0.80), granisetron plus dexa- methasone versus placebo (OR, ...and granisetron plus droperi- dol IV versus placebo (OR, ...were granisetron plus ...
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Comparison of Efficacy of Ondansetron and Granisetron in Prevention of Post Operative Nausea and Vomiting after Tonsillectomy and Middle Ear Surgery
... Hyoscine (0.2 – 0.4mg oral, i.m) and dicyclomine (10 – 20mg oral) are useful for the prophylaxis of motion sickness. They probably act by blocking conduction of nerve impulses across a cholinergic link in ...
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Comparative safety of serotonin (5-HT3) receptor antagonists in patients undergoing surgery: a systematic review and network meta-analysis
... ondansetron, granisetron, dolasetron, tropisetron, and dolasetron plus dexamethasone were administered during surgery [52, 60, 68, 69, 76, 79, 96, 100, 105, 106, 118, 124, 128, 133, 137, 139, 144, ...
13
Pharmacokinetics, safety, and efficacy of APF530 (extended-release granisetron) in patients receiving moderately or highly emetogenic chemotherapy: results of two Phase II trials
... In C2005-01, various factors were assessed for their effect on the plasma profile of granisetron after APF530 administration. Minor differences were seen in the phar- macokinetic profile related to chemotherapy ...
10
FORMULATION OF AN INSITU FORMING INJECTABLE SUSTAINED RELEASE SPONGE OF GRANISETRON HYDROCHLORIDE
... drug Granisetron Hydrochloride in a sponge forming gelatin matrix as a dry powder for reconstitution into a suspension to be injected into the body forming a sponge insitu intended to release the drug over a ...
8
Antiemetic efficacy and safety of granisetron or palonosetron alone and in combination with a corticosteroid for ABVD therapy-induced nausea and vomiting
... although the nausea and vomiting in 24 patients were not. The CC rates were not significantly different be- tween the granisetron and palonosetron groups during the overall, acute, and delayed phases (Fig. 1). The ...
7
Preformulation Studies of Rapid Dissolving Films Containing Granisetron Hydrochloride
... The humble tablet, and its alter ego, the two piece hard gelatin capsule, remains at the forefront in terms of oral dosage form. Present situation that may be seen somewhat surprising considering the production, ...
5
FORMULATION AND EVALUATION OF CHITOSAN BASED BUCCAL PATCH OF GRANISETRON HYDROCHLORIDE
... Granisetron hydrochloride is most commonly used as an antiemetic agent in treatment associated with cancer chemotherapy induced nausea and vomiting. If the dosage form is designed in sustain release it provide ...
11
Formulation of Rapid Dissolving Films Containing Granisetron Hydrochloride and Ondansetron Hydrochloride
... The oral mucosa is conveniently and easily accessible and therefore allows uncomplicated application of dosage ...the oral cavity without the need for water or ...
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A comparative evaluation of effect of intravenous premedication with ondansetron versus granisetron on hemodynamics and sensory-motor blockade produced by intrathecal hyperbaric 0.5% bupivacaine
... antagonists. Granisetron, in contrast to ondansetron, which acts on mixed receptors, strongly and selectively binds to the 5-HT3 receptors with minimal or no affinity for other 5-HT receptors, or dopaminergic, ...
8
Comparison of analgesic effect of different doses of granisetron in combination with lidocaine for intravenous regional anesthesia
... After getting the demographic information and recording the vital signs and percentage of arterial oxygen saturation, 2 intravenous access, one was used in the dorsal vein of hand that is being operated and the other was ...
6
Design, Development, Characterization and in-vitro Evaluation of Medicated Chewing Gum: Granisetron Hydrochloride
... drug Granisetron Hydrochloride for steady drug release coupled with adequate release properties from medicated chewing ...of Granisetron Hydrochloride from the medicated chewing gum formulations are showed ...
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