Orofacial Clefts (OFCs)
Congenital malformations and medical conditions associated with orofacial clefts in children in Burkina Faso
... Clefts, lip and/or palate (CL/Ps) are the most common craniofacial birth defects and represent about 15% of all birth defects [1]. They occur isolated in most cases, but 15 – 48% of the cases are associated with ...
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Maternal periconceptional consumption of sprouted potato and risks of neural tube defects and orofacial clefts
... and orofacial clefts (OFCs) are relatively common congenital anomalies that have a significant impact on infant mortality, health, and quality of life [1 – ...
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Non Random Distribution of Human Orofacial Clefts in Ghana: Gene Environment Interactions
... Human orofacial clefts (OFCs) are congenital anomalies that result from the breakdown of normal mechanisms that regulate the formation of the human ...of clefts in the study population were ...of ...
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An assessment of orofacial clefts in Tanzania
... Orofacial clefts have long been known to be associated with other congenital defects, though the frequency and type of associated malformations observed varies consid- erably across studies ...with ...
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Ten-year experience of more than 35,000 orofacial clefts in Africa
... of clefts of the lip (CL) is the physical deformity and the associated social and psychiatric morbidity ...unrepaired orofacial cleft greatly alters a child’s ability to integrate into the social and ...
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Prevalence of non syndromic orofacial clefts: based on 15,094,978 Chinese perinatal infants
... Non-syndromic orofacial clefts (NSOFC), which include cleft lip and palate (CLP), cleft lip only (CLO), and cleft palate only (CPO), contains a range of disorders affecting the lips and oral cavity [1, ...
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Epidemiological characteristic of Orofacial clefts and its associated congenital anomalies: retrospective study
... the highest incidence of orofacial clefts among Native Americans (3.6/1.000), followed by Asians (2–1.82/ 1.000), Caucasians (1/1.000), and Africans (0.3/1.000) [39, 40]. Racial differences affect more CL/P ...
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Immunisation Status of Children Born with Orofacial Clefts Who Visited the Komfo Anokye Teaching Hospital (KATH) Multidisciplinary Cleft Clinic
... Background: The Ghana Expanded Programme on Immunisation recommends that children receive Bacillus Calmette-Guerin (BCG) and Oral Polio Vaccine (OPV) at birth; three doses of Penta vaccine and OPV at 6, 10 and 14 weeks ...
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A comparison of DNA methylation in newborn blood samples from infants with and without orofacial clefts
... Epigenetic changes, in particular DNA methylation, can mediate both genetic and environmental factors and may advance the understanding of the molecular patho- genesis of orofacial clefts [14]. Several ...
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Original Article Thyroid cancer causal gene FOXE1 involved in orofacial clefts in Western Han Chinese
... Abstract: FOXE1 is causal gene for thyroid cancer and has been identified to play an essential role in non-syndromic orofacial clefts (NSOCs) among European population, but its effects remain controversial ...
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Study of risk factors related to the orofacial clefts in Eastern Azerbaijan, Iran: Population-based from 2000 to 2015
... Some materials such as Vitamins (especially folic acid with or without vitamins) vitamin B1and B6, myo-inositol, zinc, iron and riboflavin are protective factors in orofacial clefts. 11-13 However, some ...
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The Correlation between Maternal Exposure to Air Pollution and the Risk of Orofacial Clefts in Infants: a Systematic Review and Meta-Analysis
... and orofacial cleft anomalies ...cause orofacial cleft anomalies are not well understood, but include mutations in fetal DNA that interfere with cellular apoptosis, anoxic events, oxidative damage, and ...
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Dose-dependent Effect of Folic Acid on the Prevention of Orofacial Clefts
... of orofacial clefts was seen only after the use of folic acid during the critical period of primary and secondary palate develop- ment, ie, during the first and second months of gestation ...of ...
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Facial morphometrics of children with non-syndromic orofacial clefts in Tanzania
... aged 4 to 120 months. The mean age of the CL/P group was 29.4 ± 31.8 months and the mean age of the control group was 54.1 ± 34.5 months, the difference largely result- ing from a greater number of infants in the CL/P ...
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Neurodevelopmental and Academic Outcomes in Children With Orofacial Clefts: A Systematic Review
... with clefts were more likely to score below a commonly used threshold for identifying learning problems and more likely than their peers to receive special education ...
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Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery
... graphical, and socioeconomic factors and mothers’ general health status. The term “orofacial cleft” covers a wide range of disorders affecting the lips and oral cavity. Typically, cleft lip (CL) (World Health ...
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Classification Systems for Orofacial Clefts
... palate, thus omitting specification for conditions such as congenital scars of the lip or incomplete lip muscula ture. Also both classifications are weak in descriptions of palatopharyngeal incompetence and displacement ...
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Determinants of health-related and oral health-related quality of life in adults with orofacial clefts: a cross-sectional study
... the last week (74.0%). Overall, 75% of the sample received additional procedures to primary plastic surgery. Three individuals with CP had never undergone any treatment. Of the 59 patients with CLP, five did not undergo ...
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Health care service utilization and Medicaid costs among childen with and without orofacial clefts in North Carolina, 1995-2002
... children with OFC are at an increased risk of being born LBW and/or preterm, especially if they have an associated syndrome and/or another birth defect (160, 161). This study also found that the majority of children had ...
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PubMedCentral-PMC4990026.pdf
... Objective: to assessed the prevalence of diabetes mellitus (DM) and drug abuse in mothers of children with orofacial clefts (OFC). Methods: 325 women who had children (0-3y) with clefts were ...
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