The P. falciparum genetic diversity map and function
Genetic diversity of Plasmodium vivax and Plasmodium falciparum in Honduras
... Plasmodium falciparum from endemic areas in Honduras. Genetic diversity of ama-1, msp-1 and csp was investigated for ...high genetic diversity was observed within Plasmodium isolates ...
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Genetic diversity and population structure of Plasmodium falciparum in the Philippines
... Population genetic analyses based on polymorphisms of 10 microsatellite loci of the parasite were conducted on 92 isolates from three provinces (Kalinga, Palawan, and Davao del Norte) with different malaria ...of ...
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Genetic diversity of Plasmodium falciparum in human malaria cases in Mali
... that P. falciparum genetic diversity level is particularly high in ...Such diversity may constitute an obstacle to control malaria as genetic polymorphism may facilitate parasite ...
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Genetic diversity of Plasmodium falciparum populations in southeast and western Myanmar
... in the face of malaria elimination, the information pro- vided herein may serve as the baseline data for continued epidemiological surveillance in these endemic regions. It is interesting to note that although this study ...
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Plasmodium falciparum genetic diversity and malaria diagnosis in Kenyan population
... (GLP) guidelines. 2.2. Study site and sample collection The study was conducted between August and November 2016 in the Matayos Health Centre in Busia County, a malaria endemic site approximately 80 km northeast of Lake ...
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Genetic evidence for contribution of human dispersal to the genetic diversity of EBA 175 in Plasmodium falciparum
... Thai P. falciparum popula- tion were ...of P. falciparum eba-175 alleles from across the world revealed an Asian-specific basal cluster in a phylogenetic ...Thai P. falciparum ...
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Evaluation of the population structure and genetic diversity of Plasmodium falciparum in southern China
... the P. falciparum populations from South China were primarily structured into two major clusters by STRUCTURE ...tinguishing P. falciparum cases from each ...
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Genetic diversity of Plasmodium falciparum and distribution of drug resistance haplotypes in Yemen
... the genetic diversity of Plasmodium falciparum in Yemen and mutations of drug resistant genes, to elucidate parasite structure and distribution of drug resistance genotypes in the ...
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Genetic diversity and population structure of Plasmodium falciparum in Thailand, a low transmission country
... of P. falciparum in Thailand and its consequence In this study, both a spatial and a temporal distribution of ...P. falciparum haplotypes collected in the same year and over two years were ...
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Diversity in Requirement of Genetic and Epigenetic Factors for Centromere Function in Fungi
... centromere function of various in vitro-constructed minichromosomes was demon- strated in ...its function, which is readily achieved when a plasmid having the full-length centromere is present, is a time- ...
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Genetic diversity of the merozoite surface protein 3 gene in Plasmodium falciparum populations in Thailand
... the P. falciparum population structure in Ubon Ratchatani was similar to that at Kanchanaburi, since the two populations shared the same three MSP-3 ...that P. falciparum popula- tions in ...
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Chemical Genetic Approaches for Elucidating Protease Function and Drug-Target Potential in Plasmodium Falciparum
... characterization of SERA5 revealed a number of anomalies in addition to the non-canonical active site, further complicating any rational drug discovery efforts centering on SERA5. Proteases represent a highly druggable ...
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Relationship between Plasmodium falciparum malaria prevalence, genetic diversity and endemic Burkitt lymphoma in Malawi
... Our study has some limitations. By its design, it precludes us from distinguishing whether the association precedes or follows the development of eBL 29 . The use of hospital cases and controls is a limitation because, ...
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Genetic diversity of vaccine candidate antigens in Plasmodium falciparum isolates from the Amazon basin of Peru
... Results also showed two non-synonymous substitutions in R1 and R2 regions of Pfama-1. The extensive number of non-synonymous polymorphisms outside R1 and R2 described in this study revealed that this gene could undergo ...
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Genetic diversity of Plasmodium falciparum isolates from Baka Pygmies and their Bantu neighbours in the north of Gabon
... lation genetic structure of P. falciparum in ...and genetic diversity of P. falciparum observed in Baka demonstrates a sig- nificant transmission of the parasite in this ...
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Spatio temporal analysis of the genetic diversity and complexity of Plasmodium falciparum infections in Kedougou, southeastern Senegal
... Background: Genetic analyses of the malaria parasite population and its temporal and spatial dynamics could provide an assessment of the effectiveness of disease control ...The genetic diversity of ...
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Genetic diversity of expressed Plasmodium falciparum var genes from Tanzanian children with severe malaria
... The genetic sequence diversity of var genes of P. falciparum isolates from Tanzanian children is large and its relationship to disease severity has been ...
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Genetic diversity of Plasmodium falciparum isolates from uncomplicated malaria cases in Ghana over a decade
... of genetic diversity in parasite populations in high transmission areas as a re- sult of genetic recombination poses a threat to the iden- tification of antigenic epitopes for malaria vaccine ...
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Structure, function and genetic diversity of glucosyltransferase IV (GtrIV) of Shigella flexneri
... The virulence plasmi d p WRl 00 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri.. and Amara, S.G.[r] ...
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Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism
... allelic diversity was observed for CLTCL1 in all species for which populations were analyzed, including humans, chimpanzees and ...population genetic data provided support for the maintenance of high ...
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