p/sup -/-n/sup -/ collector structure
<p>Efficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO<sup>®</sup> and OTEMTO<sup>®</sup> studies: a subgroup analysis by age</p>
... years, n=749; 65 years to ,75 years, n=674; 75 years to ,85 years, n=186; $85 years, n=12) in OTEMTO and 5,162 patients (40 years to ,65 years, n=2,654; 65 years to ,75 years, ...
10
<em>N</em>-n-butyl haloperidol iodide inhibits H<sub>2</sub>O<sub>2</sub>- induced Na<sup>+</sup>/Ca<sup>2+</sup>-exchanger activation via the Na<sup>+</sup>/H<sup>+</sup> exchanger in rat ventricular myocytes
... Fisher Scientific (Waltham, MA, USA). Anti-MEK, anti- phosphorylated (p)-MEK, anti-ERK, and anti-p-ERK antibodies were from Cell Signaling Technology (Danvers, MA, USA), anti- NCX from Santa Cruz ...
11
<p>An Immunoscore System Based On CD3<sup>+</sup> And CD8<sup>+</sup> Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma</p>
... Overall, 106 patients with colorectal cancer were included (Table 1). The sex ratio (Men/Women: 64/ 42) was equal to 1.5 and the mean age for Men was 62.07 years [33 to 84 years], whereas for Women it was 61.98 years [25 ...
11
<p>Addition Of A Sleeve To The Etanercept Autoinjector (Enbrel<sup>®</sup> MyClic<sup>®</sup>) Improves Ease Of Use In Patients With Rheumatoid Arthritis</p>
... Patients and methods: Twenty-four adult patients (16 female) with RA and varying degrees of manual dexterity impairment took part in this user study. Written informed consent was supplied by each patient prior to ...
8
Tobramycin administered by the TOBI<sup>®</sup> Podhaler<sup>®</sup> for persons with cystic fibrosis: a review
... Notes: Gray circles, subjects randomized to receive 112 mg TiP twice daily; black circles, subjects randomized to receive 300 mg TiS twice daily; open circles, subjects randomized to receive matching placebo treatment ...
10
Comparison of outcomes of conventional WaveLight<sup>®</sup> Allegretto Wave<sup>®</sup> and Technolas<sup>®</sup> excimer lasers in myopic laser in situ keratomileusis
... Method: A retrospective, comparative case series of 442 eyes matched for age and myopia: half each were treated with Allegretto’s wavefront-optimized algorithm and Technolas PlanoScan. Out- come measures were ...
10
<p>Remicade<sup>®</sup> (infliximab): 20 years of contributions to science and medicine</p>
... Thus, the phase II/III program had answered all three initial questions about long-term TNF blockade with Remicade: 1) mAbs could be administered repeatedly as maintenance therapy, and s[r] ...
40
<p>An integrated safety analysis of combined acetaminophen and ibuprofen (Maxigesic<sup>®</sup>/ Combogesic<sup>®</sup>) in adults</p>
... Analysis of the safety data pooled from multiple repeated- dose Phase II/III clinical studies illustrates the excellent tolerability and safety of multiple FDC APAP/IBP oral tablet dos[r] ...
14
<p>TearCare<sup>®</sup> system extension study: evaluation of the safety, effectiveness, and durability through 12 months of a second TearCare<sup>®</sup> treatment on subjects with dry eye disease</p>
... the P-values were the result of separate tests of whether the mean difference = 0 for each follow-up time ...the P-values were from simple mixed-effects linear models (with no covariates) that allow for ...
10
Laser-based measurements of <sup>18</sup>O/<sup>16</sup>O stable isotope ratios (δ<sup>18</sup>O) in wine samples
... A commercial, OA-ICOS liquid water isotope analyzer (LWIA, Los Gatos Research, Mountain View, CA, USA) was used to measure natural waters, prepared ethanol-in-water standards, p[r] ...
8
<p>Safety And Efficacy Of Princess<sup>®</sup> FILLER Lidocaine In The Correction Of Nasolabial Folds</p>
... Subjects received the initial treatment to both NLFs on day 0, with an optional touch-up treatment at week 2, if the investigator was not satis fi ed with the result of the fi rst treatmen[r] ...
8
<p>Comparison of head-mounted perimeter (imo<sup>®</sup>) and Humphrey Field Analyzer</p>
... Spearman’s rank-order correlation coefficient was calculated for correlations between HFA and i-H type, i-F type, and i-T. Bland–Altman plots were used to analyze the systematic errors of both; a straight line ...
13
Designing of CD8<sup>+</sup> and CD8<sup>+</sup>-overlapped CD4<sup>+</sup> epitope vaccine by targeting late and early proteins of human papillomavirus
... allotypes including HLA-A*01:01, HLA-A*02:06, HLA- A*11:01, HLA-A*23:01, HLA-A*26:01, HLA-A*29:02, HLA-A*30:02, HLA-A*32:01, HLA-A*68:01, HLA- B*08:01, HLA-B*15:01, HLA-B*35:01, HLA-B*39:01, HLA-B*58:01, HLA-C*03:03, ...
19
Amelioration of concanavalin A-induced autoimmune hepatitis by magnesium isoglycyrrhizinate through inhibition of CD4<sup>+</sup>CD25<sup>-</sup>CD69<sup>+</sup> subset proliferation
... Based on our present results, MGL improving Con A- induced liver injury also may be partly related with down- regulation of inflammasome expression and inhibiting apoptosis of thy[r] ...
11
<p>Pretreatment detection of circulating and tissue CD133<sup>+ </sup>CD44<sup>+</sup> cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer</p>
... Descriptive data in the form of mean, median, range, SD, and percentages were used. Mann–Whitney U-test was used to find a relation between two groups of ordinal variables, chi-squared test between ≥ 2 groups of ...
12
Downregulation of CD44 reduces doxorubicin resistance of CD44<sup>+</sup>CD24<sup>-</sup> breast cancer cells
... We carried out primary culture of 21 tumors from 21 differ- ent patients, 15 samples exhibiting tumors that had grown with many single cells surrounding the tumor tissue. Cells from 15 samples were left to freely ...
8
Developments in administration of growth hormone treatment: focus on Norditropin<sup>®</sup> Flexpro<sup>®</sup>
... In this review, developments in the adminis- tration of growth hormone treatment for children and adults are discussed, with a particular focus on the most recently available pen devic[r] ...
8
<p>Partial sciatic nerve ligation leads to an upregulation of Ni<sup>2+</sup>-resistant T-type Ca<sup>2+</sup> currents in capsaicin-responsive nociceptive dorsal root ganglion neurons</p>
... ricated from borosilicate glass capillaries (Science Products, Hofheim, Germany) using a P-97 Flaming/Brown Micro- pipette Puller (Sutter Instrument Company, Novato, CA, USA). One cell per culture dish was ...
13
<p>Comparison of clinical effects of two latanoprost 0.005% solutions (Xalatan<sup>®</sup> and Arulatan<sup>®</sup>) in primary open-angle glaucoma or ocular hypertensive patients: a randomized clinical trial</p>
... All these informations considered, latanoprost was the fi rst PA 8,9 to become commercially available and is fre- quently employed as initial glaucoma monotherapy. The drug is an analog of the prostaglandin F2 α and ...
6
<p>Radiation therapy-induced reactive oxygen species specifically eliminates CD19<sup>+</sup> IgA<sup>+</sup> B cells in nasopharyngeal carcinoma</p>
... cells sup- press in fl ammation by secreting anti-microbial antibodies, whereas CD19 + CD138 − IgA + cells negatively regulate anti- tumor effectors by expressing PD-1 and producing TGF- β ...
11