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Paget disease of bone

Paget disease of bone

Paget disease of bone

... rare bone disease that shares many clinical features with but is distinct from PD ...Canadian Paget families and several unrelated patients ...familial Paget cases ...

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Paget disease of skeleton – Pictorial essay

Paget disease of skeleton – Pictorial essay

... “Paget disease of bone” in Indian Journal of Radiology ...“Paget disease (case report)” in Indian Journal of Medical Sciences ...“Paget disease of bone” in Indian ...

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Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant

Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant

... early-onset Paget disease and frontotemporal dementia (IBMPFD) ...opathy, Paget disease of bone, and frontotemporal demen- tia (FTD) ...Paget’s disease, and 30% for FTD ...

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Clinical Reasoning: Progressive proximal weakness in a 56-year-old man with bone pain

Clinical Reasoning: Progressive proximal weakness in a 56-year-old man with bone pain

... Rimmed vacuoles are a nonspecific finding in many myo- pathies, including sporadic IBM (sIBM) and myofibrillar myopathy (MFM). As noted previously, the patient’s pattern of muscle involvement was not typical for sIBM. There ...

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Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease

Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease

... and bone lesions that are characteristic of PD, since pagetic lesions are focal even in patients carrying germline p62 mutations and some individuals harboring p62 mutations fail to develop PD ...

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Skull radiographs as a guide for diagnosing systemic disorders (Pictorial Atlas)

Skull radiographs as a guide for diagnosing systemic disorders (Pictorial Atlas)

... This is due to failure to replace immature woven bone with mature lamellar bone. Mabry syndrome - Mental retardation with hyperphosphatasia. Although the entire skeleton may be involved the skull ...

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GATA3 is a sensitive marker for primary genital extramammary paget disease: an immunohistochemical study of 72 cases with comparison to gross cystic disease fluid protein 15

GATA3 is a sensitive marker for primary genital extramammary paget disease: an immunohistochemical study of 72 cases with comparison to gross cystic disease fluid protein 15

... Among patients with invasive EMPDs (type Ib and Ic), some will develop metastatic disease at the time of presen- tation or in their subsequent disease courses. In the SEER data, 17.1% patients with invasive ...

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Outcomes of oblique lateral interbody fusion for degenerative lumbar disease in patients under or over 65 years of age

Outcomes of oblique lateral interbody fusion for degenerative lumbar disease in patients under or over 65 years of age

... the disc in true lateral view was marked on the skin. Standard preoperative preparation of surgical field was done. For single-level fusion, 2.5–3.0-cm skin incision was made centered in the projection of the target seg- ...

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Prognostic significance of mammary Paget’s disease in Chinese women: a 10 year, population-based, matched cohort study

Prognostic significance of mammary Paget’s disease in Chinese women: a 10 year, population-based, matched cohort study

... reported that patients who have PD with IDC have a greater risk of axillary lymph node (LN) metastasis than patients with IDC alone. Because of the uncommon nature of the disease, published research studies tend ...

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Significant pain relief with loading dose zoledronic acid in bone metastases is only seen in patients with elevated initial serum C telopeptide (CTX)

Significant pain relief with loading dose zoledronic acid in bone metastases is only seen in patients with elevated initial serum C telopeptide (CTX)

... of bone resorption markers, such as CTX, can be an effective approach in identifying patients at high risk of developing bone metastases and in prevent- ing SRE of which pain is the most frequently ...

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Pattern of Bone Disease in Maintenance Haemodialysis Patients in Malaysia

Pattern of Bone Disease in Maintenance Haemodialysis Patients in Malaysia

... Pattern of Bone Disease in Maintenance Haemodialysis Patients in Malaysia Med J Malaysia Vol 41 No 2 June 1986 PATTERN OF BONE DISEASE IN MAINTENANCE HAEMODIALYSIS PATIENTS IN MALAYSIA M SEGASOTHY A K[.] ...

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Bone resorption predicts for skeletal complications in metastatic bone disease

Bone resorption predicts for skeletal complications in metastatic bone disease

... in bone and its breakdown products are being increasingly investigated as markers of bone ...metastatic bone disease (Lipton et al, ...between bone resorption markers, especially Ntx, ...

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Cross Sectional study on Metabolic Bone disease in non cholestatic chronic liver disease.

Cross Sectional study on Metabolic Bone disease in non cholestatic chronic liver disease.

... measures bone mineral content (in gms) and bone area (in square centimeters), then calculates "areal" BMD in g/cm2 by dividing bone mineral content and bone ...

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Radiographic features of osteogenesis imperfecta

Radiographic features of osteogenesis imperfecta

... A positive diagnosis of OI can be difficult, particularly in young children (before the age of 2 years) with mild forms of OI (types I, IV) and when there are few or no obvious extraskeletal manifestations and no ...

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Estimated number of prevalent cases of metastatic bone disease in the US adult population

Estimated number of prevalent cases of metastatic bone disease in the US adult population

... metastatic bone disease, estimates of prevalence in this study cannot be properly interpreted as measures of the prevalence of 5-year history of metastatic bone disease, because not all ...

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Osteoporosis: A cross sectional study

Osteoporosis: A cross sectional study

... The main goal of osteoporosis treatment is to avoid fractures with the use of therapies that increase BMD. Osteofar 10mg is a medicine sent by the Ministry of Health the carriers of osteoporosis. This is the commercial ...

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Multiple Myeloma associated Bone Disease

Multiple Myeloma associated Bone Disease

... Baseline data from a randomized controlled trial indicate that patients with newly diagnosed multiple myeloma generally had lower physical function compared to the normal population, and this goes particularly for ...

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A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease

A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease

... on bone remod- eling, and in particular how the tumor influences auto- crine and paracrine signaling in the osteoclast and osteoblast cell populations (see ...of bone remodeling in the absence of tumor ...

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A short account of metastatic bone disease

A short account of metastatic bone disease

... mediate bone deposition: platelet derive growth fac- tor (PDGF), ligands of the Wnt signalling pathway, insu- lin-like growth factor (IGF), transforming growth factor- b (TGF-b), bone morphogenic proteins ...

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Cartilage to bone transitions in health and disease

Cartilage to bone transitions in health and disease

... disc disease have increased alkaline phosphatase activity, and also in contrast to healthy IVDs express significant levels of hypertrophic differentiation markers, including collagen type-X, osteoprotegerin (OPG), ...

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