Paget’s disease
Paget’s disease derived in situ from reserve cell hyperplasia, squamous metaplasia, and squamous cell carcinoma of the esophagogastric junction: a case report
... Traditionally, EMPD has been surgically managed, es- pecially in the early stage of the disease. Achieving ad- equate margins for the primary lesions is an important factor in reducing the risk of recurrence. In ...
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Spectrum of Imaging Findings in Paget’s Disease of the Breast—A Pictorial Review
... et al. [19] evaluated pre-operative mammography and MRI findings in nine biopsy proven cases of Paget’s dis- ease and concluded that Paget ’ s disease of breast with underlying DCIS can be ...
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Current perspectives on bisphosphonate treatment in Paget’s disease of bone
... the effects of symptomatic treatment with intensive bispho- sphonates therapy in 1,324 patients with Paget’s disease of bone, with a median follow-up period of 3 years (ranging from 2 to 5 years). The symptomatic ...
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Anal gland adenocarcinoma in situ with pagetoid spread: a case report
... patient, there was no visible gastrointestinal, genital, or urinary tumor, and we initially suspected primary PPD. However, immunohistochemical analysis (CK7 +, CK20 +, GCDFP15 − , CDX2 +) suggested secondary EMPD. This ...
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Paget’s disease of bone: an osteoimmunological disorder?
... specific osteoimmunological pattern associated with a given rheumatic disease. For example, bone formation markers are usually increased in all these diseases, except in osteoporosis and rheumatoid arthritis ...
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<p>Response to Pyrotinib in a Chinese Patient with Bone-Metastatic Scrotal Paget’s Disease Harboring Triple Uncommon HER2 Mutation: A Case Report</p>
... The most common location of EMPD in males is the penoscrotal junction, followed in order by the scrotum and inguinal area. 3 EMPD of the scrotum and penis is rare, which occurs predominantly in Asian males in the age ...
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Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant
... early-onset Paget disease and frontotemporal dementia (IBMPFD) ...opathy, Paget disease of bone, and frontotemporal demen- tia (FTD) ...Paget’s disease, and 30% for FTD ...Parkinson’s ...
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Current options for the treatment of Paget’s disease of the bone
... Paget’s disease of bone (PDB) is a chronic bone remodelling disorder characterized by increased osteoclast-mediated bone resorption, with subsequent compensatory increases in new bone formation, resulting in a ...
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Original Article Expression of vascular endothelial growth factor and basic fibroblast growth factor in extramammary Paget disease
... Paget’s disease (PD), also known as eczema- like cancer, was first described by James Paget in a patient with breast cancer in ...Paget’s disease (mammary Paget’s disease, MPD) and ...
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Emerging strategies and therapies for treatment of Paget’s disease of bone
... Paget’s disease of bone (PDB) is a progressive monostotic or polyostotic metabolic bone disease characterized by focal abnormal bone remodeling, with increased bone resorption and excessive, disorganized, ...
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TOXICITY STUDIES OF VANGA BHASMA (INCINERATED FORM OF TIN) PREPARED BY TWO DIFFERENT METHODS
... Dose selection: The classics of Ayurveda describe the dose of Vanga Bhasma to be from 1 Ratti to 2 Ratti(125mg to 250 mg). [7] Considering adult human dose of Vanga Bhasma i.e. 500 mg. For experimental study it was ...
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A Slight Case of Plagiary, Part I: Berenson, Paget, and Anstruther-Thomson
... Anstruther-Thonlson bared her mettle in a twenty-page letter to Costelloe on November 5, remarking at the outset that she had not heard of the matter before. She too offered her note- bo[r] ...
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Magnetic resonance enterography, colonoscopy, and fecal calprotectin correlate in colonic Crohn’s disease
... At our institution, MRE is performed using 3.0 Tesla mag- net systems (Siemens Healthcare, Berlin, Germany). Pa- tients ingest 1450 mL of a barium sulfate suspension (VoLumen; Bracco, Westbury, New York, U.S.A.) followed ...
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Disease-modifying drugs in Alzheimer's disease
... the disease include deposition of amyloid beta (A β ) peptide in so-called senile plaques and accumulation of tau protein in cells, leading to neurofibrillary tangles and pyramidal cell ...
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Moderating effects of sex on the impact of diagnosis and amyloid positivity on verbal memory and hippocampal volume
... effects of A + in preclinical stages in women. Importantly, the present results do not imply that women have larger hippocampi and thus more volume to lose. Instead, they would suggest that neural reserve could be ...
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Genome-wide association study for variants that modulate relationships between cerebrospinal fluid amyloid-beta 42, tau, and p-tau levels
... chromosomes and both are strong hits for pelvic organ prolapse. While diseases of the nervous system can cause pelvic organ prolapse, it is unlikely related to the ptau / Aβ42 relationship but may suggest that these two ...
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ALZHEIMER’S DISEASE: A REVIEW
... Alzheimer's disease clinical feature typically presents with early problems in memory and visuospatial abilities (eg, becoming lost in familiar surroundings, inability to copy a geometric design on paper), yet ...
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Book Reviews
... Objective: To emphasize the importance for health care professionals to be knowledgeable of a relatively rare form of thoracic outlet syndrome, known as Paget Schroetter syndrome. The etiology, key signs and ...
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Cognitive and imaging markers in non-demented subjects attending a memory clinic: study design and baseline findings of the MEMENTO cohort
... cular disease (self-reported history of myocardial infarc- tion, surgical bypass, stroke, peripheral artery disease, angina pectoris); for neuropsychiatric symptoms, apathy, depression, anxiety based on ...
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Vulvar Paget disease secondary to high-grade urothelial carcinoma with underlying massive vascular embolization and cervical involvement: case report of unusual presentation
... groups, distending the appendage ducts, where they were associated with foci of comedonecrosis (Fig. 2b). Intense lymphocytic infiltration could be seen under the epider- mis. The dermis and hypodermis showed diffuse ...
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